1.Low-level Light/Laser Therapy in Dermatology.
Mira CHOI ; Eun Jin DOH ; Dong Hun LEE
Korean Journal of Dermatology 2016;54(4):241-248
Low-level laser or light therapy (LLLT) was used to accelerate wound healing without the use of thermal effects in the early days. Although the exact mechanism of LLLT is still unclear, it has been recognized as a photobiomodulation process. Today, LLLT is being credited as a non-invasive treatment modality, and in particular, being widely applied in the field of dermatology. In this review, we summarize the basic principles and clinical applications of LLLT to provide an up-to-date guidance on its practical and safe uses. Further studies are needed to elucidate the mechanism of action of LLLT in various indications, and to determine the wavelength and dose for optimal clinical use.
Dermatology*
;
Low-Level Light Therapy
;
Phototherapy
;
Wound Healing
2.Regional Variation of Human Skin Surface Temperature
Chan Mi LEE ; Seon Pil JIN ; Eun Jin DOH ; Dong Hun LEE ; Jin Ho CHUNG
Annals of Dermatology 2019;31(3):349-352
3.A Questionnaire Survey for Proper Education of Atopic Dermatitis.
Eun Jin DOH ; Mira CHOI ; Ji Soo LIM ; Hyun Sun YOON ; Dong Hun LEE ; Kyu Han KIM
Korean Journal of Dermatology 2017;55(6):329-336
BACKGROUND: Therapeutic education is important for successful management of atopic dermatitis (AD). OBJECTIVE: To provide effective therapeutic education, clear common misunderstandings, and answer questions regarding AD among patients and caregivers. METHODS: A questionnaire survey was conducted for patients and caregivers who visited the Department of Dermatology at Seoul National University Hospital, Seoul, Korea, regarding the course, etiology, and management of AD. RESULTS: Among the 327 subjects who participated in the study, only 35.2% were aware of the natural course of AD, which usually improves with age. Many subjects (53.2%) misinterpret AD relapse as resistance to topical steroids. We found that 87.8% of subjects were under the impression that improvement in a patient's immunity can improve the symptoms of AD. Dietary restriction was considered an essential management strategy, and 59.0% of subjects agreed to delay the initiation of weaning foods. Most subjects did not have accurate information about cleansing methods, and 30.9% of subjects reported that they used only water without any cleanser. We noted that 47.5% of subjects obtained information regarding AD from medical doctors who they considered the most reliable sources (82.5%). Subjects preferred printed materials (41.3%) over seminars or video-clips to obtain educational information. CONCLUSION: Therapeutic education regarding the course, etiology, and management of AD using printed materials put together by physicians would be a valuable tool for the effective management of AD. Institutional support such as educational programs covered by the National Health Insurance Service is required.
Caregivers
;
Dermatitis, Atopic*
;
Dermatology
;
Education*
;
Humans
;
Korea
;
National Health Programs
;
Recurrence
;
Seoul
;
Steroids
;
Water
;
Weaning
4.A Questionnaire Survey for Proper Education of Atopic Dermatitis.
Eun Jin DOH ; Mira CHOI ; Ji Soo LIM ; Hyun Sun YOON ; Dong Hun LEE ; Kyu Han KIM
Korean Journal of Dermatology 2017;55(6):329-336
BACKGROUND: Therapeutic education is important for successful management of atopic dermatitis (AD). OBJECTIVE: To provide effective therapeutic education, clear common misunderstandings, and answer questions regarding AD among patients and caregivers. METHODS: A questionnaire survey was conducted for patients and caregivers who visited the Department of Dermatology at Seoul National University Hospital, Seoul, Korea, regarding the course, etiology, and management of AD. RESULTS: Among the 327 subjects who participated in the study, only 35.2% were aware of the natural course of AD, which usually improves with age. Many subjects (53.2%) misinterpret AD relapse as resistance to topical steroids. We found that 87.8% of subjects were under the impression that improvement in a patient's immunity can improve the symptoms of AD. Dietary restriction was considered an essential management strategy, and 59.0% of subjects agreed to delay the initiation of weaning foods. Most subjects did not have accurate information about cleansing methods, and 30.9% of subjects reported that they used only water without any cleanser. We noted that 47.5% of subjects obtained information regarding AD from medical doctors who they considered the most reliable sources (82.5%). Subjects preferred printed materials (41.3%) over seminars or video-clips to obtain educational information. CONCLUSION: Therapeutic education regarding the course, etiology, and management of AD using printed materials put together by physicians would be a valuable tool for the effective management of AD. Institutional support such as educational programs covered by the National Health Insurance Service is required.
Caregivers
;
Dermatitis, Atopic*
;
Dermatology
;
Education*
;
Humans
;
Korea
;
National Health Programs
;
Recurrence
;
Seoul
;
Steroids
;
Water
;
Weaning
5.A Case of Peritonitis caused by Chryseobacterium meningosepticum in a Patient Treated with Peritoneal Dialysis.
Hyang Mo KOO ; Fa mee DOH ; Eun Jin KIM ; Ea Wha KANG ; Suk Kyun SHIN ; Tae Ik CHANG
Korean Journal of Nephrology 2011;30(3):339-342
Chryseobacterium meningosepticum is rarely encountered as a pathogen causing peritonitis in peritoneal dialysis (PD) patients. We report a case of peritonitis due to Chryseobacterium meningosepticum, which was treated successfully with intraperitoneal (IP) vancomycin and ciprofloxacin, and without PD catheter removal. Peritonitis was developed in a 53-year-old PD patient on the third hospital day. Although empirical IP treatment with cefazolin and tobramycin was initiated and maintained for 3 days, the fever and signs of peritonitis persisted. Antibiotics were changed to cefoperazone/sulbactam, amikacin, and vancomycin due to clinical deterioration. After 3 days of vancomycin use, leukocyte count in PD fluid was less than 100/mm3 and the patient became asymptomatic. On seventh day after the onset of peritonitis, Chryseobacterium meningosepticum was isolated from initial dialysate sample, and this strain was susceptible to ciprofloxacin, piperacillin, and piperacillin/tazobactam. Accordingly, we changed the antibiotics to ciprofloxacin and vancomycin, which were given for the total of 14 days. Even though Chryseobacterium meningosepticum is an uncommon causative organism of peritonitis in PD patients, this report suggests that vancomycin and ciprofloxacin are effective as empiric therapy, and early suspicion and appropriate antimicrobial therapy are crucial to the successful treatment of peritonitis due to Chryseobacterium meningosepticum without catheter removal.
Amikacin
;
Anti-Bacterial Agents
;
Catheters
;
Cefazolin
;
Chryseobacterium
;
Ciprofloxacin
;
Fever
;
Humans
;
Leukocyte Count
;
Middle Aged
;
Peritoneal Dialysis
;
Peritonitis
;
Piperacillin
;
Sprains and Strains
;
Tobramycin
;
Vancomycin
6.A case of transfusion-related acute lung injury induced by anti-human leukocyte antigen antibodies in acute leukemia.
Sun Mi JIN ; Moon Ju JANG ; Ji Young HUH ; Myoung Hee PARK ; Eun Young SONG ; Doyeun OH
Korean Journal of Hematology 2012;47(4):302-306
Transfusion-related acute lung injury (TRALI) is a noncardiogenic pulmonary edema that occurs during or within 6 hours after transfusion. Risk factors for TRALI, which is relatively common in critically ill patients, include recent surgery, hematologic malignancy, and sepsis. Here, we report a case of TRALI induced by anti-human leukocyte antigen (anti-HLA) class II antibodies (HLA-DR) occurring after transfusion of platelet concentrates in a patient with acute leukemia. Although most patients with TRALI show improvement within 48-96 hours, our patient's condition rapidly worsened, and he did not respond to supportive treatment. TRALI is a relatively common and serious adverse transfusion reaction that requires prompt diagnosis and management.
Acute Lung Injury
;
Antibodies
;
Blood Group Incompatibility
;
Blood Platelets
;
Critical Illness
;
Hematologic Neoplasms
;
Humans
;
Leukemia
;
Leukocytes
;
Pulmonary Edema
;
Risk Factors
;
Sepsis
7.Effect of Splint and Nd-YAG Laser in Microsurgical Reanastomosis of Rabbit Fallopian Tube.
Jin Hong KIM ; Young Me DOH ; Eun Jung KIM ; Ki Wook JUNG ; Dong Jin KWON ; Jang Heub KIM ; Jin Woo LEE ; Soo Pyung KIM
Korean Journal of Obstetrics and Gynecology 1997;40(10):2178-2186
To study tubal adhesion, tubal patency and histologic difference under light, electronic microcopy in a site of anastomosis, authors performed three anastomosis surgery in rabbit fallopian tube;1-layer and 2-layer anastomosis in splint-not-used group(group 1) and in splint-used group(group 2) and laser anastomosis in splint-used group(group 3). 10 rabbits were used in each group, therefore the total number of experimental rabbits in 3 groups were 30. The results were as follows; 1. The degree of gross adhesion in group II was significantly high as compared with other groups but there was no difference between left and right tube in the degree of adh- esion in each group(Table 1). 2. The incidence of tubal patency in group I was significantly high(89%) as compared with group I(44%). Especially, the incidence of tubal patency in group III was significantly high(100%) but there was no difference between left and right tube in incidence of tubal patency in each group. 3. Inflammatory cell infiltration appeared in each group on optical microscopic examin- ation. Especially, fibrosis and inflammatory cell infiltration appeared more in group II but there was no statistically significant difference. And there was no significant difference between left and right tube in each group. 4. Transmission electron microscopic examination of group I, as compared with normal control group, showed increase of microvilli and secretory granules and decrease in size of epithelial cell. Epithelial cell was morphologically transformed but maintained the original structure comparatively. TEM examination of group II, as compared with normal control group, showed decrease of microvilli and secretory granules and flattening of epithelial cell. It showed that epithelial cell vanished in it's original structure. TEM examination of group III, as compared with normal control group, showed decrease of microvilli and increase of secretory granules and morphological transformation of epithelial cell. Group III showed the resemblence to normal control group. From the above results, in reversal tuboplasty and tubal factor infertility, it is consi- dered that simple splint-used anastomosis or splint-used anastomosis with Nd-YAG laser will improve the successful rate of tubal anastomosis.
Epithelial Cells
;
Fallopian Tubes*
;
Female
;
Fibrosis
;
Incidence
;
Infertility
;
Lasers, Solid-State*
;
Microvilli
;
Rabbits
;
Secretory Vesicles
;
Splints*
8.A Case of Langerhans Cell Histiocytosis with Sclerosing Cholangitis.
Jae Chul HWANG ; Doh Hyun KIM ; Eun Hee LEE ; Jai Hak JEUNG ; Jin Young SHIM ; Jae Youn CHEONG ; Do Hyun KIM ; Kee Myung LEE ; Byung Moo YOO ; Jin Hong KIM
Korean Journal of Gastrointestinal Endoscopy 2003;26(1):56-60
Langerhans cell histiocytosis is a rare disorder with abnormal proliferation of histiocytes. Besides the infiltration of a variety of organs, patients with Langerhans cell histiocytosis can develop sclerosing cholangitis, with bile duct involvement, progressive fibrosis, and cirrhosis. We report a case of Langerhans cell histiocytosis with sclerosing cholangitis. Endoscopic retrograde cholangiopancreatography revealed multiple strictures and dilatations of left intrahepatic and extrahepatic bile duct. Endoscopic biopsy of common bile duct showed diffuse infiltration of histiocytes and eosinophiles in lamina propria. Immunohistochemical stain showed positive reactions for S-100 and CD1a and a negative reaction for cytokeratin in infiltrating histiocytes.
Bile Ducts
;
Bile Ducts, Extrahepatic
;
Biopsy
;
Cholangiopancreatography, Endoscopic Retrograde
;
Cholangitis, Sclerosing*
;
Common Bile Duct
;
Constriction, Pathologic
;
Dilatation
;
Eosinophils
;
Fibrosis
;
Histiocytes
;
Histiocytosis, Langerhans-Cell*
;
Humans
;
Keratins
;
Mucous Membrane
9.Minimal Change Nephrotic Syndrome Developed after Thymectomy in a Patient with Thymoma.
Fa Mee DOH ; Seon Jung JANG ; Hyang Mo KOO ; Eun Jin KIM ; Hye Sun SHIN ; Seung Hyeok HAN ; Shin Wook KANG ; Kyu Hun CHOI ; Tae Hyun YOO
Korean Journal of Nephrology 2011;30(4):404-408
We report a case of patient with malignant thymoma, who developed nephrotic syndrome several years after thymectomy. This 38-year-old man was diagnosed as myasthenia gravis and malignant thymoma and underwent thymectomy in 2004. Tumor resection and systemic chemotherapy were performed after recurrence in pleura in 2006. He also took pyridostigmine to control his symptoms of myasthenia gravis after thymectomy. Four years later, even though there was no evidence of recurrence of thymoma, he developed a nephrotic syndrome and was diagnosed as a minimal change disease on renal biopsy. After pulse therapy with methylprednisolone followed by oral administration of prednisolone therapy, nephrotic syndrome was improved.
Administration, Oral
;
Adult
;
Biopsy
;
Humans
;
Methylprednisolone
;
Myasthenia Gravis
;
Nephrosis, Lipoid
;
Nephrotic Syndrome
;
Pleura
;
Prednisolone
;
Pyridostigmine Bromide
;
Recurrence
;
Thymectomy
;
Thymoma
10.Clinical Significance of Erosive and/or Small Ulcerative Lesions in the Colon and Terminal Ileum: Short-term Follow-up Study.
Doh Hyun KIM ; Kwang Jae LEE ; Yeong Bae KIM ; Eun Hee LEE ; Hyun Ju SONG ; Jin Hong KIM ; Ki Baik HAHM ; Sung Won CHO
The Korean Journal of Gastroenterology 2004;44(6):321-327
BACKGROUND/AIMS: Various etiologies and diseases may be related to erosions and/or small ulcers without gross inflammatory changes in the surrounding mucosa found in the colon and terminal ileum during colonoscopy. However, studies on follow-up of these lesions are rare. Thus, we investigated the clinical significance of these lesions and their characteristics helpful for differential diagnosis. METHODS: We reviewed the data of 183 patients with colonoscopically observed erosive or small ulcerative lesions (<2 cm), and analyzed them according to the location, number, and size of lesions, histopathologic findings, chief complaints, laboratory findings, changes of symptoms, and changes in lesions during 4-12 week follow-up period. RESULTS: Histopathologic findings of these lesions included acute nonspecific inflammation, chronic nonspecific inflammation, Crohn's disease, tuberculous colitis, ischemic colitis, Behcet's disease, cytomegalovirus infection, eosinophilic colitis, ulcerative colitis or pseudomembranous colitis, but most of them were nonspecific (84%). In patients with nonspecific inflammation, histopathologic findings, symptoms, location and multiplicity of the lesions were not prognostic factors for the persistency of symptoms and lesions during follow-up period. Two patients with acute inflammation, who showed no improvement in symptoms and lesions, were later diagnosed as Crohn's disease. CONCLUSIONS: Erosive or small ulcerative lesions without macroscopic inflammatory changes in the surrounding mucosa during colonoscopy, are mainly nonspecific. However, careful follow-up is required when the symptoms and/or lesions are not improved.
Adolescent
;
Adult
;
Aged
;
Colon/*pathology
;
Colonoscopy
;
English Abstract
;
Female
;
Humans
;
Ileum/*pathology
;
Intestinal Diseases/*diagnosis/pathology
;
Male
;
Middle Aged
;
Ulcer/pathology