1.A Case of Hair Follicle Nevus.
Doo Hwan KIM ; Eun Jung CHYUNG ; See Yong PARK
Korean Journal of Dermatology 1985;23(5):711-713
We report one case of hair follicle nevus, benign highly differentiating appendageal skin tumor of hair follicle. It arises from pluripotential cells that have formed during life. This patient is a 40-year-old woman who had a localized brownish plaque on the leht cheek for three years. Histologic study revealed many small but mostly mature hair follicles consistent with hair follicle nevus.A Case of Cutaneous Periarteritis Nodosa
Adult
;
Cheek
;
Female
;
Hair Follicle*
;
Hair*
;
Humans
;
Nevus*
;
Polyarteritis Nodosa
;
Skin
2.A case of Vulvar Syringoma.
Doo Hwan KIM ; Eun Jung CHUNG ; See Yong PARK
Korean Journal of Dermatology 1985;23(3):396-398
A 25-year-old female was seen because of rnultiple, asymptornatic papular eruptions on the vulvar area since 1 year ago. She had been suffered from palmar hyperhidrosis for 3 years. A skin biopsy specimen from the vulval lesion revealed characteristic findings of syringoma.
Adult
;
Biopsy
;
Female
;
Humans
;
Hyperhidrosis
;
Skin
;
Syringoma*
3.A case of Solitary Glomus Tumor.
Doo Hwan KIM ; Eun Jung CHUNG ; See Yong PARK
Korean Journal of Dermatology 1985;23(3):392-395
A 72 years old man had an 1 x 1cm sized, solitary glomus tumor on the right knee joint and had suffered from sharp, episodic pain and tenderness, radiating to the right thigh and the buttock for about 20 years. Simple surgical excision was performed for removal of the tumor mass and the subjective symtoms. There is no recurrence until now.
Aged
;
Buttocks
;
Glomus Tumor*
;
Humans
;
Knee Joint
;
Recurrence
;
Thigh
4.Fingertip Dermatoglyphic Patterns in Patients with Atopic Dermatitis and their Families.
Doo Hwan KIM ; Eun Jung CHYUNG ; See Yong PARK
Korean Journal of Dermatology 1986;24(1):28-34
Although we made a comparision of fingertip dermatoglyphic patterns between R7 patients with atopic dermatitis(Femals: 54, Male: 35) and 73 their families without atopic dermatitis, no significant results were obtained. So, we compared secondly our results of 2 groups with those of two thousand nonatopic, normal Koreans, as control. Results are as follows: ] In comparison with control, a significant increase in the ulnar loop pattern was detected in families(p<0, ()5), not atopic dermatitis. p. No significant differ ence between right hands and left hands in all three g f OUpS. In atopic dermatitis and control groups, 1 st and 4 th digits showed mostly whorl pattern, and 3 rd and 5 th digits had more ulnar loop pattern than others. Rut families had mostly ulnar loop pattern at all digits except 4 th digit, wl..orl pattern. 4. Each of atopic dermatitis, family and control group had 13, 79% (whor1: 8. 05% ulnar loop: 5 75%), 15. 49p; (whorl: 4. 23%, ulnar loop: 11. 27%), 15. 78%(whorl: 8, 52% ulnar loop: 7. 1 %, arch: 0. 05%), of same dermatoglyphic pattern on all ten digits. Especially, ulnar loop pattern in fanilies was detected significantly higher than other two groups(p<0. 05). Average incidences of bilateral symmetry of pattern type between right and left digits were 78.57%, 74. 67% and 78.74% respectively in atopic dermatitis, family and control group.
Dermatitis, Atopic*
;
Dermatoglyphics*
;
Hand
;
Humans
;
Incidence
;
Male
5.Ipsilateral Tibial Shaft Fractures and Knee Ligament Injuries
Eun Woo LEE ; Soo Yong KANG ; Jung Hwan SEO
The Journal of the Korean Orthopaedic Association 1990;25(5):1317-1322
Nine patients with ipsilateral tibial shaft fractures and knee ligament injuries were retrospectively reviewed to determine the methods of the diagnosis and the results of the treatment. The incidence of this combined injuries was 5% in one hundred and eighty two tibial shaft fractures. The injuries of posterior cruciate ligament were combined most freqently. Five of nine patients were open fractures. Bone union was obtained in all cases and the mean duration of bone union was 22.5 weeks. Athroscopy and stress X-ray for the cruciate ligament were helpful to diagnose this combined injures. The ligament injuries were surgically managed in eight and conservatively in one. Better results were obtained when this combined injuries were operated early, but four of nine patients were disabled. The results suggest that the examination of the knee is necessary to document ligamentous injuries that occur with tibial shaft fractures.
Diagnosis
;
Fractures, Open
;
Humans
;
Incidence
;
Knee
;
Ligaments
;
Posterior Cruciate Ligament
;
Retrospective Studies
6.Synovial fluid osmolarlity of human knee.
Eun Woo LEE ; Soo Yong KANG ; Jung Hwan SEO
Journal of the Korean Knee Society 1991;3(1):15-18
No abstract available.
Humans*
;
Knee*
;
Synovial Fluid*
7.A case of male pseudohermaphroditism due to 17 ?hydroxylase deficiency.
Chang Soo PARK ; Me Lee LEE ; Eun Hwan JUNG ; Jung Gu KIM
Journal of Korean Society of Endocrinology 1993;8(3):363-369
No abstract available.
46, XY Disorders of Sex Development*
;
Humans
;
Male*
8.Gram-negative Septicemia after Infliximab Treatment in an Infant with Refractory Kawasaki Disease.
Jin Hwan LEE ; Jung Min YOON ; Jae Woo LIM ; Kyong Og KO ; Eun Jung CHEON
Korean Journal of Pediatric Infectious Diseases 2014;21(3):225-230
Kawasaki disease (KD) is an immune-mediated disease which is a leading cause of acquired cardiovascular disease in developed country. Recently, tumor necrosis factor-alpha (TNF-alpha) blocker, infliximab has been considered a promising option for patients with refractory KD. Although chronic use of a TNF-alpha blocker could increase risk of opportunistic infections, a few studies have documented that use of infliximab was safe without serious adverse effects in patients with KD. We observed serious bacterial infection after infliximab treatment in an infant with refractory KD. Our patient was a 5-month-old male infant diagnosed with KD who did not respond to repeated doses of intravenous immunoglobulin. We effectively treated him with a single infusion of infliximab (5 mg/kg), but gram-negative (Acinetobacter lwoffii) septicemia developed after infliximab infusion. Therefore, we report a case of serious septicemia after treatment with infliximab, and suggest considering the risk of severe infection when deciding whether to prescribe infliximab to an infant with refractory KD.
Bacterial Infections
;
Cardiovascular Diseases
;
Developed Countries
;
Humans
;
Immunoglobulins
;
Infant*
;
Male
;
Mucocutaneous Lymph Node Syndrome*
;
Opportunistic Infections
;
Sepsis*
;
Tumor Necrosis Factor-alpha
;
Infliximab
10.Fragile X Syndrome : Clinical Characteristics and EEG Findings.
Hee Jung CHUNG ; Kwang Eun CHA ; Sook Hwan LEE
Journal of the Korean Pediatric Society 1997;40(8):1110-1119
PURPOSE: Fragile X syndrome is an X-llinked genetic disorder and is characterized by mental retardation, learning disability, behavior disorder, and autism with typical elongated face, large ears, and macro-orchidism. Recent reports have focused attention on the EEG finding of this syndrome, which is a particular paroxysmal pattern during sleep (mono or diphasic centrotemporal spikes) and awake state (background slowing). In this study, we analyzed the clinical characteristics of fragile X syndrome patients and observed whether a particular EEG pattern is associated with this syndrome or not. METHODS: 7 cases of fragile X syndrome, diagnosed at Sowha Children's Hospital and Cha General Hospital from August 1993 to February 1995, were analyzed retrospectively in terms of typical phenotypes and clinical & EEG characteristics. The patients were diagnosed by Southern blotting and polymerase chain reaction (PCR) method. RESULTS: 1) The subjects were all male and the mean age was 5.8 years old (2Y-11Y). 2) Typical phenotype of long elongated face, macro-orchidism, large ears, and large head are noted in 2/3 of the subject. 3) Developmental delay, mental retardation, learning disability, attention deficit, hyperactivity, and autism are noted in 2/3 of the subject. 4) Seizure is noted in one case and EEG was performed in 6 cases, regardless of the presence of seizures. Abnormal findings including centrotemporal sharps and background slowing are noted in one case, each. 5) By molecular diagnostic methods including Southern blotting and PCR, 3 cases of affected male and 4 of normal transmitting male were diagnosed. CONCLUSIONS: 1) The typical phenotype of fragile X syndrome is long elongated face, macro-orchidism, large ears and large head. 2) The non-physical characteristics of fragile X syndrome are developmental delay, mental retardation, learning disability, attention deficit, hyperactivity, and autism. 3) The characteristic EEG findings of fragile X syndrome known by literature are noted in 2 among 6 cases, which means the specificity is high even though the sensitivity is low. This allows us to propose this EEG pattern as an important "marker" in the diagnosis of fragile X syndrome. However, the number of the subject is too small to conclude now. Further accumulation of cases is reguired.
Autistic Disorder
;
Blotting, Southern
;
Diagnosis
;
Ear
;
Electroencephalography*
;
Fragile X Syndrome*
;
Head
;
Hospitals, General
;
Humans
;
Intellectual Disability
;
Learning Disorders
;
Male
;
Pathology, Molecular
;
Phenotype
;
Polymerase Chain Reaction
;
Retrospective Studies
;
Seizures
;
Sensitivity and Specificity