1.Antitumor effect of ursolic acid against inbred hepatoma in CBA/J mouse.
Jae Chung HAH ; Tae Hyong RHEW ; Eun Sang CHOE ; Hae Young CHUNG ; Kun Young PARK
Journal of the Korean Cancer Association 1992;24(6):790-794
No abstract available.
Animals
;
Carcinoma, Hepatocellular*
;
Mice*
2.A Case of Congenital T Cell Lymphoblastic Lymphoma.
Eun Sun YOO ; Young Mi HONG ; Kyung Hee KIM ; Hae Soo GYU ; Eun Chul CHUNG
Journal of the Korean Pediatric Society 1994;37(9):1296-1304
T cell lymphoblastic lymphoma is characterized by immature lymphoid cells that are indistinguishable from the lymphoblasts and prolymphocytes of acute lymphoblastic leukemia. Several characteristic clinical features of lymphoblastic lymphoma, with include a high male-to-female ratio, a relatively high incidence in older children and young adults, the frequent presence of mediastinal involvement at the time of diagnosis. Also, this disease is rapidly progressive, and early dissemination to the bone marrow, blood, and central nervous system leads to the evolution of a picture resembling a acute lymphoblastic leukemia. We have experienced a rare case of congenital T-cell lymphoblastic lymphoma in which 1/365 year old female newborn had generalized multiple irregular protruding mass on her body. On bone marrow biopsy, CSF analysis, ultrasonogram and whole body MRI studies. We found metastasized tumor mass to, orbit, abdominal cavity, bulva, skin, and lower extremities. Histopathologically, specimen from mass on the right thigh showed diffuse infiltration of poorly differentiated and immature lymphoid cells in the skelectal muscle and subcutaneous soft tissue. By immunophenotyping studies using anti T cell and B cell monoclonal antibody, these cells were reactive with UCHL-1, MB2, but unreactive with MB1, L26. Based on these findings, the lesion was diagnosed as lymphoblastic lymphoma of the T-cell type, which occurred congenitally. Most T cell lymphoblastic lymphoma are noted, but congenital case was not reported. So we report it with a brief review of literature.
Abdominal Cavity
;
Biopsy
;
Bone Marrow
;
Central Nervous System
;
Child
;
Diagnosis
;
Female
;
Humans
;
Immunophenotyping
;
Incidence
;
Infant, Newborn
;
Lower Extremity
;
Lymphocytes
;
Magnetic Resonance Imaging
;
Orbit
;
Precursor Cell Lymphoblastic Leukemia-Lymphoma*
;
Skin
;
T-Lymphocytes
;
Thigh
;
Ultrasonography
;
Young Adult
3.Laryngotracheoesophageal Cleft Type III A Report of 1 Case.
Myung Su LEE ; Yuong Eun LEE ; Eun Ae PARK ; Gyoung Hee KIM ; Eun Chul CHUNG ; Hae Soo GYE
Journal of the Korean Pediatric Society 1995;38(5):719-724
No abstract available.
4.A Case of Autoimmune Hemolytic Anemia Associated with Acute Viral Hepatitis B.
Chong Kyu WOO ; Eun Kyung CHOI ; Hae Ryung CHUNG ; Dong Heuk KEUM
Journal of the Korean Pediatric Society 1987;30(9):1034-1039
No abstract available.
Anemia, Hemolytic, Autoimmune*
;
Hepatitis B*
;
Hepatitis*
5.Two Cases of Tsutsugamushi Disease in Children.
Eun Saing JEE ; Hae Lim CHUNG ; Hoan Jong LEE ; Hyung Ro MOON
Journal of the Korean Pediatric Society 1988;31(11):1509-1515
No abstract available.
Child*
;
Humans
;
Scrub Typhus*
6.The Performance Evaluation of Public Municipal Hospitals: Data Envelopment Analysis and Panel Analysis.
Eun Young CHUNG ; Young Jun SEO ; Hae Jong LEE
Health Policy and Management 2015;25(4):295-306
This study aims to examine the performance of public municipal hospitals through the analysis of data envelopment analysis, efficiency, profitability, and publicness by using panel data during period from 2006 to 2010. The main findings of the study are as follows. First, as a result of efficiency analysis during the period from 2006 to 2010, it was revealed that the number of staff by each job category, labor cost ratio, the number of operating beds need to be decreased. Second, the performance data represented by the indicators of efficiency, profitability and publicness were complementary and showed a tendency of being increased or decreased in same direction. Third, from the result of panel analysis, the efficiency was mainly influenced by the structural factors, while the profitability was influenced by managerial factors, and the publicness by medical environment. In conclusion, in order to enhance the performance of public municipal hospitals in Korea, it is important to harmonize the effort for efficiency, financial and policy support by central and local government, and the continuous participation of community residents.
Hospitals, Municipal*
;
Korea
;
Local Government
7.Late-Onset Citrobacter koseri Endophthalmitis with Suture Exposure after Secondary Intraocular Lens Implantation.
Korean Journal of Ophthalmology 2011;25(4):285-288
A 54-year-old male patient was seen in clinic for ocular pain and decreased vision in the right eye with duration of two days. He underwent a cataract operation for his right eye 12 years ago, then a sclera-fixated secondary intraocular implantation and pars plana vitrectomy three years ago due to intraocular lens dislocation. At the initial visit, his visual acuity was restricted to the perception of hand motion. An edematous cornea, cells, flare with hypopyon, and exposed suture material at were observed at the six o'clock direction by slit lamp. Vitreous opacity was noted from B-scan ultrasonography. The patient was diagnosed with late-onset endophthalmitis and an intravitreal cocktail injection was done. On the next day, the hypopyon was aggravated, and therefore a pars plana vitrectomy was performed. A vitreous culture tested positive for Citrobacter koseri. After 12 weeks, the best corrected visual acuity of the right eye improved to 0.7 and a fundus examination revealed a relatively normal optic disc and retinal vasculature. We herein report the first case of endophthalmitis caused by Citrobacter koseri in Korea. Exposed suture material was suspected as the source of infection in this case and prompt surgical intervention resulted in a relatively good visual outcome.
Anti-Bacterial Agents/administration & dosage
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Cataract Extraction/adverse effects
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Citrobacter koseri/*isolation & purification
;
Diagnosis, Differential
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Endophthalmitis/diagnosis/*microbiology/therapy
;
Enterobacteriaceae Infections/diagnosis/*microbiology/therapy
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Eye Infections, Bacterial/diagnosis/*microbiology/therapy
;
Follow-Up Studies
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Humans
;
Intravitreal Injections
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Lens Implantation, Intraocular/*adverse effects
;
Male
;
Microscopy, Acoustic
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Middle Aged
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Surgical Wound Infection/diagnosis/*microbiology/therapy
;
Sutures/adverse effects/microbiology
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Visual Acuity
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Vitrectomy
;
Vitreous Body/*microbiology
8.Anthropometric and Nutrition Status of Institutional Children.
Hae Kyung CHUNG ; Young Eun CHANG
Korean Journal of Community Nutrition 1999;4(1):3-10
This study was designed to investigate the malnutrition rate with anthropometric indices for the nutrient intake of 74 children aged 4-12 years old in three child welfare institutions in Cheonan city. The average heights and weights of the children are much lower than the Korean average height and weight. The mean BMI is 17.0+/-1.53. In terms of heighter-for-age, 16.0% of the samples beong to below -2 standard deviation from the mean of the reference group. In terms of weight-for-age, 16.0% of the children belong to below -2 standard deviation. In terms of weight-for-height, 4.0% of the children belong to below -2 standard deviation. The standard deviation scores(Wt/Age, Ht/Age) indicate negative signs for seventy to eighty percent of the children. This is due to the lower consumption of the important nutrients that children consumed and almost all nutrients much less than the recommended daily allowances. Special nutrition welfare policies and programs targetings child welfare institutions should be developed to provide adequate nutrition for children in residential care.
Child Welfare
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Child*
;
Chungcheongnam-do
;
Humans
;
Malnutrition
;
Nutritional Status*
;
Recommended Dietary Allowances
;
Weights and Measures
9.Diagnostic significance of computed tomography in gastric cancer
Eun Young KANG ; Sang Hoon CHA ; Hae Young SEOL ; Kyoo Byung CHUNG ; Won Hyuck SUH
Journal of the Korean Radiological Society 1985;21(5):755-765
Gastric cancer is the most common gastrointestinal malignancy in Korea. Identification and evaluation ofgastric mass lesions and regional-distant metastases by abdominal CT scan are important for the treatment planningand prognostic implications of gastric cancer patients. Author reviewed CT scan are important for the treatemntplaning and prognostic implications of gastric cancer patients. Author reviewed CT scan of 61 cases of pathologyproven gastric cancer, retrospectively, for recent 20 months from July 1983 to Feb. 1985 at department ofradiology, Korea University, Hae Wha Hospital. The results were as follows: 1. There were 50 cases of advanced adenocarcinoma, 8 cases of early gastric cancer, 2 cases of leiomyosarcoma, and 1 case of lymphoma in total 61cases. 2. The sex ratio of male to female was 2:1. Age distribution was from 24 to 75 year old and peak incidencewas in 6th decade. 3. The most frequent site of involvement with gastric cancer was gastric antrum in 51%. 4. 48of the 50 patients with advanced gastric adenocarcinoma(96%) had a wall thickness greater than 1 cm, and all of 8cases of early gastric cancer had a wall thickness less than 1 cm. Regional lymph node tumor infiltration wasfound in 100% of gastric wall thickness greater than 2.0cm, in 64% of cases of 1.5 to 2.0cm, in 50% of cases of1.9 to 1.5cm, and 12.5% of cases of less than 1.0cm. 5. In a comparison of enlargement of reginal lymph node by CTscan to tumor infiltration of regional lymph node by histology, senitivity was 52%, specificity was 87%, and reliability was 66%. 6. The structures involved by distant metastases of these cases were the retroperitoneallymph node in 15, liver in 8, and pancrease in 3. 7. The diagnostic accuracy of CT staging was considered about68% by correlation of the surgical and histological findings. 8. The CT scan is one of the accurate and simpletool for evaluation of size, shape, extent, as well as distant metastases in the cases of gastric malignancies.
Adenocarcinoma
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Age Distribution
;
Female
;
Humans
;
Korea
;
Leiomyosarcoma
;
Liver
;
Lymph Nodes
;
Lymphoma
;
Male
;
Neoplasm Metastasis
;
Pancreas
;
Pancrelipase
;
Pyloric Antrum
;
Retrospective Studies
;
Sensitivity and Specificity
;
Sex Ratio
;
Stomach Neoplasms
;
Tomography, X-Ray Computed
10.MR Findings of Degenerating Parenchymal Neurocysticercosis.
Yul LEE ; Eun A CHUNG ; Ik YANG ; Hae Jung PARK ; Soo Young CHUNG
Journal of the Korean Radiological Society 1996;34(6):695-701
PURPOSE: To evaluate MR imaging findings of degenerating parenchymal neurocysticercosis and to determine the characteristics which distinguish it from other brain diseases. METHODS: MR imagings of 19 patients (56 lesions)of degenerating parenchymal neurocysticercosis were retrospectively evaluated, focusing on the size and locationof lesions, signal intensity patterns of cyst fluid and wall, the extent of the surrounding edema and features of contrast enhancement. RESULTS: Degenerating parenchymal neurocysticercosis was located in gray or subcortical white matter in 89.3% of 56 lesions(50/56); most of these (98.2%) were smaller than 2cm in diameter. Cyst fluidsignal was hyperintense relative to CSF on T1 and proton density weighted images (92.9%). A hypointense signal rimof the cyst wall was noted in the lesions on proton density (92.9%) and T2 weighted (98.2%) images. Surrounding edema was mostly mild. Peripheral rim enhancement was noted in all lesions, and this was frequently irregular and lobulated (67.9%) with a focal defect in the enhancing rim (41.1%). CONCLUSION: Findings which could be helpfulin distinguishing degenerating parencymal neurocysticerosis from other brain diseases are as follows : small, superficial lesions ; hyperintense signal of the cyst fluid on T1 and proton density weighted images ; hypointense signal of the cyst wall on proton density and T2 weighted images ; relatively mild extent of surrounding edema,and peripheral rim enhancement which is frequently irregular and lobulated with a focal defect in the enhancingrim.
Brain Diseases
;
Cyst Fluid
;
Cysticercosis
;
Edema
;
Humans
;
Magnetic Resonance Imaging
;
Neurocysticercosis*
;
Parasites
;
Protons
;
Retrospective Studies