1.Adhesion and invasion of shed endometrium in an in-vitro model for endometriosis using amnion.
Mi Gyung KOONG ; Jin Hyun JEON ; Gyung Nam KO ; Eun Soo KIM ; Jong Young JEON ; In Soo KANG
Korean Journal of Obstetrics and Gynecology 2000;43(12):2237-2242
No abstract available.
Amnion*
;
Endometriosis*
;
Endometrium*
;
Female
2.Cystic Hepatocellular carcinoma: a case report.
Chi young JUNG ; Eun Jung JUNG ; Soon Chan HONG ; Gyung hyuck KO
Korean Journal of Hepato-Biliary-Pancreatic Surgery 2000;4(1):157-159
Cystic hepatocellular carcinoma is unusal, and visualization of the cystic components within hepatic mass lesion have suggested that the lesions were metastatic tumors, primary cystic tumors such as biliary cystadenocarcinoma or cystic papillary cholangiocarcinoma. Although hepatic lesions can be well characterized by noninvasive imaging modalities, findings are often nonspecific. Even for cystic hepatic lesions a considerable diagnostic differential exists. The diagnosis of cystic hepatocellular carcinoma was difficult before the microscopic examination of the biopsy speciemen because of very rare. Then we report an unusual of cystic hepatocellular carcinoma without liver cirrhosis.
Biopsy
;
Carcinoma, Hepatocellular*
;
Cholangiocarcinoma
;
Cystadenocarcinoma
;
Diagnosis
;
Liver Cirrhosis
3.Comparison of Isolation rate of the Pathogenic Microorganisms According to Stool Culture Methods.
Eun Gyung KO ; Chang Jung KIM ; Key Earn LEE ; Jihyun CHO ; Young Hoe MOON
Korean Journal of Clinical Microbiology 1998;1(1):57-62
BACKGROUND: In developed countries, food-born diseases have decreased and hospital laboratory have taken more simple method rather than complex enrichment-selective methods. But detection rate of pathogenic bacteria in stool culture was not so high. METHODS: We mixed 4 pathogenic bacteria (S. typhi, S. flexneri, V. cholerae and Y. enterocolitica) with 3 stool specimens from healthy persons (for Y. enterocolitica, 5 specimens) and innoculated directly or after enrichment (105 bacteria/plate). After proper incubation, we counted suspected colonies and calculated true positive rate after identification of each colonies. RESULTS: For S. typhi, in the case of direct innoculation on the MacConkey, XLD and SS agar, positive rate of selected colonies were below 36.6%. After enrichment in SF broth for 8 hours, the rate were 80.0%, 83.0% and 70.0% respectively. For S. flexneri, the rates were 86.7%, 100%, 93.3% in direct innoculation, and were highest after enrichment in GN broth for two hours (93.3% in MacConkey and 100.0% in both XLD and SS agar). For V. cholerae, inspite of screening by catalase and oxidase tests, positive rate of selected colonies were 0% (0/7 colonies) in direct innoculation on the MacConkey. After enrichment in APW about 1 day and on TCBS agar, the rate were 100%. For Y. enterocolitica, after incubation at room temperature for 2 days, most selected colonies were Y. enterocolitica on CIN media. CONCLUSION: For more efficient detection of pathogenic bacteria in stool culture, combination of direct innoculation on MacConkey agar and on one or two selective media after proper enrichment process, should be considered.
Agar
;
Bacteria
;
Catalase
;
Cholera
;
Developed Countries
;
Humans
;
Laboratories, Hospital
;
Mass Screening
;
Oxidoreductases
;
Salmonella
;
Shigella
;
Vibrio
;
Yersinia
4.The Association between Helicobacter pylori Infection and Body Weight among Children.
Jun Sik CHOI ; Kyung Og KO ; Jae Woo LIM ; Eun Jeong CHEON ; Gyung Min LEE ; Jung Min YOON
Pediatric Gastroenterology, Hepatology & Nutrition 2016;19(2):110-115
PURPOSE: We performed to reveal the association between the Helicobacter pylori infection and body weight among children. METHODS: Out retrospective study included patients who underwent the H. pylori immunoglobulin G testing at Konyang University Hospital between March 2011 and June 2014. These patients were classified as seropositive (28 boys, 27 girls; mean age: 9.89±3.28 years) or seronegative (55 boys, 54 girls; mean age: 9.84±3.02 years). Next, we compared various characteristics between the seropositive and negative groups, as well as between obese children (body weight ≥90th percentile) and non-obese children (body weight <90th percentile). Furthermore, we compared the change in body weight after 2 months of treatment with amoxicillin, clarithromycin and omeprazole among the 55 seropositive children (14 treated children and 41 non-treated children). RESULTS: There were no differences in the weights and laboratory data for the 55 seropositive children and 109 seronegative children (weight; 40.96±18.11 kg vs. 36.85±13.72 kg, respectively; p=0.14). And, there was no difference in the prevalence of H. pylori infection among the 29 obese and 135 non-obese children (p=0.581). However, after 2 months of eradication, the 14 treated patients exhibited a significant weight gain (+0.91±0.52 kg), compared to the 41 non-treated patients (-0.29±1.16 kg, p=0.025). CONCLUSION: Our findings present that obesity was not associated with the H. pylori infection, although H. pylori eradication led to significant increase in body weight.
Amoxicillin
;
Body Weight*
;
Child*
;
Clarithromycin
;
Disease Eradication
;
Female
;
Helicobacter pylori*
;
Helicobacter*
;
Humans
;
Immunoglobulin G
;
Obesity
;
Omeprazole
;
Prevalence
;
Retrospective Studies
;
Weight Gain
;
Weights and Measures
5.Age-adjusted plasma N-terminal pro-brain natriuretic peptide level in Kawasaki disease.
Heul JUN ; Kyung Ok KO ; Jae Woo LIM ; Jung Min YOON ; Gyung Min LEE ; Eun Jung CHEON
Korean Journal of Pediatrics 2016;59(7):298-302
PURPOSE: Recent reports showed that plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) could be a useful biomarker of intravenous immunoglobulin (IVIG) unresponsiveness and coronary artery lesion (CAL) development in Kawasaki disease (KD). The levels of these peptides are critically influenced by age; hence, the normal range and upper limits for infants and children are different. We performed an age-adjusted analysis of plasma NT-proBNP level to validate its clinical use in the diagnosis of KD. METHODS: The data of 131 patients with KD were retrospectively analyzed. The patients were divided into 2 groups—group I (high NT-proBNP group) and group II (normal NT-proBNP group)—comprising patients with NT-proBNP concentrations higher and lower than the 95th percentile of the reference value, respectively. We compared the laboratory data, responsiveness to IVIG, and the risk of CAL in both groups. RESULTS: Group I showed significantly higher white blood cell count, absolute neutrophil count, C-reactive protein level, aspartate aminotransferase level, and troponin-I level than group II (P<0.05). The risk of CAL was also significantly higher in group I (odds ratio, 5.78; P=0.012). IVIG unresponsiveness in group I was three times that in group II (odds ratio, 3.35; P=0.005). CONCLUSION: Age-adjusted analysis of plasma NT-proBNP level could be helpful in predicting IVIG unresponsiveness and risk of CAL development in patients with KD.
Aspartate Aminotransferases
;
C-Reactive Protein
;
Child
;
Coronary Vessels
;
Diagnosis
;
Humans
;
Immunoglobulins
;
Immunoglobulins, Intravenous
;
Infant
;
Leukocyte Count
;
Mucocutaneous Lymph Node Syndrome*
;
Neutrophils
;
Peptides
;
Plasma*
;
Reference Values
;
Retrospective Studies
;
Troponin I
6.Pulmonary carcinoid tumor presented with recurrent pneumonia in adolescence.
Eun Sil PARK ; Ji Suk PARK ; Jae Young LIM ; Joung Hee LEE ; Gyung Hyuck KO
Korean Journal of Pediatrics 2006;49(7):805-809
The incidence of endobronchial tumor in the pediatric period is very rare and the symptoms are very close to those of respiratory tract infection. Diagnosis can be delayed because of low clinical suspicion and the many ways in which these tumors can present. We report the first case, in Korea, of a pulmonary carcinoid tumor that presented with recurrent pneumonia at the same location in adolescence. Treatment is surgical and geared towards complete resection while sparing healthy lung parenchyma. Long-term and careful follow up is recommended to detect local and distant metastasis.
Adolescent*
;
Carcinoid Tumor*
;
Diagnosis
;
Follow-Up Studies
;
Humans
;
Incidence
;
Korea
;
Lung
;
Neoplasm Metastasis
;
Pneumonia*
;
Respiratory Tract Infections
7.Lingual Squamous Cell Carcinoma Surrounded by Granular Cell Tumor
Hee Young SON ; Jin Pyeong KIM ; Gyung Hyuck KO ; Eun Jae LEE ; Seung Hoon WOO
Chonnam Medical Journal 2012;48(1):65-68
The granular cell tumor (GCT) is an uncommon, benign lesion with a preference for subcutaneous sites. In the head and neck, the tongue is the most common site, followed by the larynx. We experienced a case of a 27-year-old woman with lingual squamous cell carcinoma (SCC) surrounded by GCT. The pathological findings established that the lesion was SCC covered by GCT in the midline of the tongue. The size of the mass was very small, however, so we excised it in a diamond shape. There is an interesting association between GCTs and other malignant neoplasms. However, no causal relationship between GCT and these other carcinomas has been established. Here we report on an SCC coexisting with GCT at the same site as a median tongue lesion and review the literature.
Adult
;
Carcinoma, Squamous Cell
;
Diamond
;
Female
;
Granular Cell Tumor
;
Head
;
Humans
;
Larynx
;
Neck
;
Tongue
8.Development of autoimmune hepatitis in a psoriasis patient without immunosuppressive therapy.
Wonyong JO ; Young Sun SUH ; Sang Il LEE ; Yun Hong CHEON ; Jeongmin HONG ; Sang Su LEE ; Ji Eun KIM ; Gyung Hyuck KO ; Hyun Ok KIM
Clinical and Molecular Hepatology 2017;23(2):184-187
We present a case of a 65-year-old man with psoriasis who developed autoimmune hepatitis (AIH) without receiving immunosuppressive therapy with either anti-tumor necrosis factor-α or methotrexate. The AIH had completely resolved at 2 months after prednisolone and azathioprine therapy. This case confirms the need to consider AIH in psoriasis patients who experience new elevations in liver enzymes. To our knowledge, this is first description of the development of AIH in an immunosuppressant-naïve patient with psoriasis.
Aged
;
Azathioprine
;
Hepatitis, Autoimmune*
;
Humans
;
Liver
;
Methotrexate
;
Necrosis
;
Prednisolone
;
Psoriasis*
9.A Case of Meckel's Diverticulum Presented with Acute Abdomen in a Newborn.
Jae Young LIM ; Sun Hwa JANG ; Jae Min CHO ; Gyung Hyuck KO ; Eun Sil PARK ; Ji Hyun SEO ; Chan Hoo PARK ; Hyang Ok WOO ; Hee Shang YOUN
Korean Journal of Pediatric Gastroenterology and Nutrition 2005;8(2):222-225
Meckel's diverticulum is generally acknowledged to be the most prevalent congenital anomaly of the gastrointestinal tract. The preoperative diagnosis of Meckel's diverticulum is difficult, especially in neonates, because of the lesions ability to masquerade as one of a variety of much more common abdominal pathologies. Recently we experienced a case of perforated Meckel's diverticulum with mild inflammatory reaction, intestinal adhesion, and small bowel obstruction in a previous healthy 9-day-old neonate. The spontaneous perforation of Meckel's diverticulum in neonate is very rare but serious entity. The course was rapid and progressed to sepsis. So despite its varied presentation, Meckel's diverticulum should be kept in mind as a cause of acute abdomen in neonates.
Abdomen, Acute*
;
Diagnosis
;
Gastrointestinal Tract
;
Humans
;
Infant, Newborn*
;
Intestinal Obstruction
;
Meckel Diverticulum*
;
Pathology
;
Sepsis
10.Contrast Media-induced Sweet's Syndrome.
Young Sun SUH ; Yun Hong CHEON ; Sang Il LEE ; Gyung Hyuck KO ; Do Seon JEONG ; Tae Jin YOON ; Ji Eun KIM ; Hyun Ok KIM
Korean Journal of Dermatology 2016;54(3):226-227
No abstract available.
Sweet Syndrome*