1.Superficial Soft Tissue Masses: Sonographic and Pathologic Findings.
Gyung Eun LEE ; Kyung Ah CHUN ; Eun Duk CHANG
Journal of the Korean Society of Medical Ultrasound 2010;29(3):135-145
Superficial soft tissue masses are frequently encountered in clinical practice. Sonographic imaging is a first-choice screening modality to confirm or exclude the presence of a soft tissue mass at a site of clinical concern. In this pictorial review, we demonstrate the sonographic and pathologic findings of superficial soft tissue masses including benign and malignant lesions, which can occur in the skin and subcutaneous layer.
Mass Screening
;
Skin
2.3 Cases of Primary Hepatocellular Carcinoma First Detected During Pregnancy.
Sung Il KIM ; Soo Yeon HAN ; Hyung Dong YOON ; Eun Gyung CHUN ; Taek Sang LEE ; Jee Young LEE ; Joong Sin PARK ; Jong Gwan JEON ; Bo Hyun YOON ; Hee Chul SHIN
Korean Journal of Obstetrics and Gynecology 2000;43(12):2323-2327
No abstract available.
Carcinoma, Hepatocellular*
;
Pregnancy*
3.A Case of Complete Remission of Choriocarcinoma with Brain Metastases Treated with Multicycle High-dose MTX/EMA-CO, Intrathecal MTX and Whole Brain RT.
Eun Gyung CHUN ; Joo Won RHO ; Sang Soo SEO ; Hyung Dong YOON ; Jae Won KIM ; No Hyun PARK ; Yong Sang SONG ; Soon Bum KANG ; Hyo Pyo LEE
Korean Journal of Obstetrics and Gynecology 2001;44(1):189-193
Patients of choriocarcinoma with brain metastases are considered to have a very poor prognosis due to chemo-refractoriness and recurrence. So, selection and individualization of patients then followed by multimodality therapy are very important. We present a case of a patient who experienced twice of craniotomies due to intracranial hemorrhage and an emergent explorative laparotomy due to intestinal perforation of the metastatic sites of choriocarcinoma. She was treated with 12 cycles of high-dose MTX/EMA-CO, intrathecal MTX and WBRT. Eventually she has obtained a complete remission that ongoing for 2 years. So, we report this case with a brief review of the literatures.
Brain*
;
Choriocarcinoma*
;
Craniotomy
;
Female
;
Humans
;
Intestinal Perforation
;
Intracranial Hemorrhages
;
Laparotomy
;
Neoplasm Metastasis*
;
Pregnancy
;
Prognosis
;
Recurrence
4.Successful antibiotic treatment of Pseudomonas stutzeri-induced peritonitis without peritoneal dialysis catheter removal in continuous ambulatory peritoneal dialysis.
Sung Wook PARK ; Ji Hyeon BACK ; Seoung Woo LEE ; Joon Ho SONG ; Chun Ho SHIN ; Gyung Eun KIM ; Moon Jae KIM
Kidney Research and Clinical Practice 2013;32(2):81-83
Pseudomonas stutzeri is a Gram-negative, rod-shaped, motile, single polar-flagellated, soil bacterium that was first isolated from human spinal fluid and is widely distributed in the environment. It was isolated as an uncommon opportunistic pathogen from humans, and a few cases of P. stutzeri-induced peritonitis have been reported in patients undergoing continuous ambulatory peritoneal dialysis (CAPD). Catheter removal with antibiotic treatment is generally recommended because peritonitis by Pseudomonas species is commonly associated with catheter-related infection. Here, we describe the first case of P. stutzeri-induced peritonitis in an 82-year-old woman in Korea. She had received two antipseudomonal antibiotics, an aminoglycoside (isepamicin, Yuhan corporation, Seoul, Korea) and a fluoroquinolone (ciprofloxacin), and was successfully treated without removal of the CAPD catheter.
Aged, 80 and over
;
Anti-Bacterial Agents
;
Catheter-Related Infections
;
Catheters
;
Female
;
Humans
;
Korea
;
Peritoneal Dialysis
;
Peritoneal Dialysis, Continuous Ambulatory
;
Peritonitis
;
Pseudomonas
;
Pseudomonas stutzeri
;
Soil
5.Management of Pediatric Patients Presenting with Acute Abdomen Accompanying Dilatation of the Common Bile Duct.
Young A KIM ; Gyung Min KIM ; Peter CHUN ; Eun Ha HWANG ; Sang Wook MUN ; Yeoun Joo LEE ; Jae Hong PARK
Pediatric Gastroenterology, Hepatology & Nutrition 2018;21(3):203-208
PURPOSE: The aim of this study was to describe our treatment experiences with patients who had acute abdomen (AA) with common bile duct (CBD) dilatation. METHODS: The treatment outcomes in children with AA and CBD dilatation were retrospectively reviewed. According to the shape of the intrahepatic bile ducts on ultrasonography (US), the origin of the pain was estimated as choledochal cyst (CC) complication or choledocholithiasis in normal CBD. Patients with complicated CC underwent surgery, and patients with choledocholithiasis in a normal appearing CBD underwent symptomatic treatment initially. RESULTS: Of the 34 patients, 30 (88.2%) were female. The mean age of the patients was 6.4±4.9 (range, 0.8–17) years. Seventeen (50.0%) patients had CBD stones and 17 (50.0%) did not. Surgical treatment was performed in 20 (58.8%) patients, 2 of whom underwent preoperative stone removal with endoscopic retrograde cholangiopancreatography and an operation. Conservative treatment was applied in 12 (35.3%) patients (8 with and 4 without stones), 1 of whom developed symptom relapse and underwent an operation. Among the 8 patients with CBD stones, 4 (4/17, 23.5%) had complete resolution of the stones and recovery of the CBD diameter after conservative treatment. US findings of patients with stone showed a fusiform or cylindrical shape of the CBD in 14 (82.4%) patients. CONCLUSION: The presence of stones in the distal CBD and the US features of CBD dilatation may be helpful to diagnose and treat the causes of biliary dilatation. Conservative treatment can be considered as initial therapy in patients with uncomplicated CBD dilatation with stone.
Abdomen, Acute*
;
Bile Ducts, Intrahepatic
;
Child
;
Cholangiopancreatography, Endoscopic Retrograde
;
Choledochal Cyst
;
Choledocholithiasis
;
Common Bile Duct*
;
Dilatation*
;
Female
;
Humans
;
Recurrence
;
Retrospective Studies
;
Ultrasonography
6.Korean Nosocomial Infections Surveillance System, Intensive Care Unit Module Report: Summary of Data from July 2013 through June 2014.
Yee Gyung KWAK ; Jun Yong CHOI ; Hyeonmi YOO ; Sang Oh LEE ; Hong Bin KIM ; Su Ha HAN ; Hee Jung CHOI ; Young Keun KIM ; Sung Ran KIM ; Tae Hyong KIM ; Hyukmin LEE ; Hee Kyung CHUN ; Jae Seok KIM ; Byung Wook EUN ; Hyun Sook KOO ; Eun Hee CHO ; Young UH ; Kyungwon LEE
Korean Journal of Nosocomial Infection Control 2015;20(2):49-60
BACKGROUND: In this report, we present the annual data of the intensive care unit (ICU) module of the Korean Nosocomial Infections Surveillance System (KONIS) from July 2013 through June 2014. METHODS: We performed a prospective surveillance of nosocomial urinary tract infections (UTIs), bloodstream infections (BSIs), and pneumonia (PNEU) in 166 ICUs of 94 hospitals using the KONIS. Nosocomial infection (NI) rate was defined as the number of infections per 1,000 patient-days or device-days. RESULTS: A total of 2,843 NIs were found during the study period: 861 UTIs (846 were urinary catheter-associated), 1,173 BSIs (1,021 were central line-associated), and 809 PNEUs (498 were ventilator-associated). The rate of urinary catheter-associated UTIs was 1.21 per 1,000 device-days (95% confidence interval [CI]=1.13-1.29), and the urinary catheter utilization ratio was 0.84 (95% CI=0.839-0.841). The rate of central line-associated BSIs was 2.33 per 1,000 device-days (95% CI=2.20-2.48), and the utilization ratio was 0.53 (95% CI=0.529-0.531). The rate of ventilatorassociated PNEUs (VAPs) was 1.46 per 1,000 device-days (95% CI=1.34-1.60), and the utilization ratio was 0.41 (95% CI=0.409-0.411). In hospitals with more than 900 beds, although the ventilator utilization ratio was highest, the rate of VAPs was lower than in hospitals with 300-699 or 700-899 beds. CONCLUSION: BSIs were the most commonly reported nosocomial infections. Although device utilization ratios had increased, nosocomial infection rates did not differ significantly from those during the previous period (July 2012 through June 2013).
Cross Infection*
;
Intensive Care Units*
;
Critical Care*
;
Pneumonia
;
Prospective Studies
;
Urinary Catheters
;
Urinary Tract Infections
;
Ventilators, Mechanical
7.Maintenance Therapy of Facial Seborrheic Dermatitis with 0.1% Tacrolimus Ointment.
Hye One KIM ; Yoon Seok YANG ; Hyun Chang KO ; Gyung Moon KIM ; Sang Hyun CHO ; Young Joon SEO ; Sang Wook SON ; Jong Rok LEE ; Joong Sun LEE ; Sung Eun CHANG ; Jae We CHE ; Chun Wook PARK
Annals of Dermatology 2015;27(5):523-530
BACKGROUND: Topical calcineurin inhibitors (TCIs) have been successfully used to treat seborrheic dermatitis (SD) patients. Meanwhile, treatment of atopic dermatitis (AD) with low-dose, intermittent TCI has been proved to reduce disease flare-ups. This regimen is known as a maintenance treatment. OBJECTIVE: The aim of this trial was to investigate the efficacy and tolerability of a maintenance treatment with tacrolimus ointment in patients with facial SD. METHODS: During the initial stabilization period, patients with facial SD or AD applied 0.1% tacrolimus ointment twice daily for up to 4 weeks. Clinical measurements were evaluated on either in the whole face or on separate facial regions. When an investigator global assessment score 1 was achieved, the patient applied tacrolimus twice weekly for 20 weeks. We also compared our results with recent published data of placebo controlled study to allow an estimation of the placebo effect. RESULTS: The time to the first relapse during phase II was similar in both groups otherwise significantly longer than the placebo group. The recurrence-free curves of two groups were not significantly different from each other; otherwise the curve of the placebo group was significantly different. There were no significant differences between the 2 groups in the number of DEs, and treatment days for disease exacerbations (DEs). The adverse event profile was also similar between the 2 groups. During the 20 weeks of treatment, the study population tolerated tacrolimus ointment well. CONCLUSION: The results of this study suggest that maintenance treatment with tacrolimus may be effective in preventing the occurrence of facial SD exacerbations.
Calcineurin
;
Dermatitis, Atopic
;
Dermatitis, Seborrheic*
;
Humans
;
Placebo Effect
;
Recurrence
;
Research Personnel
;
Tacrolimus*
8.Maintenance Therapy of Facial Seborrheic Dermatitis with 0.1% Tacrolimus Ointment.
Hye One KIM ; Yoon Seok YANG ; Hyun Chang KO ; Gyung Moon KIM ; Sang Hyun CHO ; Young Joon SEO ; Sang Wook SON ; Jong Rok LEE ; Joong Sun LEE ; Sung Eun CHANG ; Jae We CHE ; Chun Wook PARK
Annals of Dermatology 2015;27(5):523-530
BACKGROUND: Topical calcineurin inhibitors (TCIs) have been successfully used to treat seborrheic dermatitis (SD) patients. Meanwhile, treatment of atopic dermatitis (AD) with low-dose, intermittent TCI has been proved to reduce disease flare-ups. This regimen is known as a maintenance treatment. OBJECTIVE: The aim of this trial was to investigate the efficacy and tolerability of a maintenance treatment with tacrolimus ointment in patients with facial SD. METHODS: During the initial stabilization period, patients with facial SD or AD applied 0.1% tacrolimus ointment twice daily for up to 4 weeks. Clinical measurements were evaluated on either in the whole face or on separate facial regions. When an investigator global assessment score 1 was achieved, the patient applied tacrolimus twice weekly for 20 weeks. We also compared our results with recent published data of placebo controlled study to allow an estimation of the placebo effect. RESULTS: The time to the first relapse during phase II was similar in both groups otherwise significantly longer than the placebo group. The recurrence-free curves of two groups were not significantly different from each other; otherwise the curve of the placebo group was significantly different. There were no significant differences between the 2 groups in the number of DEs, and treatment days for disease exacerbations (DEs). The adverse event profile was also similar between the 2 groups. During the 20 weeks of treatment, the study population tolerated tacrolimus ointment well. CONCLUSION: The results of this study suggest that maintenance treatment with tacrolimus may be effective in preventing the occurrence of facial SD exacerbations.
Calcineurin
;
Dermatitis, Atopic
;
Dermatitis, Seborrheic*
;
Humans
;
Placebo Effect
;
Recurrence
;
Research Personnel
;
Tacrolimus*