No abstract available.
Acidosis, Renal Tubular* ; Captopril*

No abstract available.
Blood Transfusion* ; Humans ; Infant, Newborn ; Infant, Premature*

No abstract available.
Urachus*

Angiomyoma is a benign soft tissue tumor that arises from the smooth muscle layer of blood vessels in the deeplayers of the dermis, or in subcutaneous tissue. It occurs as a well-encapsulated solitary mass, most of which areless than 2cm in diameter. Some patients complain of pain with or without tenderness. This tumor has apredilection for the lower extremities of middle-aged females. MRI findings of angiomyoma of the extremities haverarely been reported, and we describe these findings in two cases of angiomyoma of the hand and foot.
Angiomyoma* ; Blood Vessels ; Dermis ; Extremities* ; Female ; Foot ; Hand ; Humans ; Leiomyoma ; Lower Extremity ; Magnetic Resonance Imaging ; Muscle, Smooth ; Subcutaneous Tissue

PURPOSE: This study attempted to understand patients' and nurses' perspectives on the priority of rehabilitation nursing services using Importance-Performance Analysis (IPA). METHODS: This study used descriptive research design. Data were collected from 121 patients and 144 nurses using self-reported questionnaires. Statistical analysis included an independent t-test, analysis of variance (ANOVA), and IPA conducted using SPSS/WIN 21.0 version. RESULTS: There were no statistical differences between the patients' and nurses' mean scores on perceptions of the importance (t=-0.83, p=.409) and performance (t=-0.32, p=.751) of rehabilitation nursing services. The IPA matrix showed a difference between patients and nurses in terms of their perceived priority of nursing services. Regarding the perception of patients, "helping a patient to continue to practice bedside physiotherapy and occupational therapy", "providing information on the proper care agency and community resources", and "providing education for the prevention of complications" fell in the "concetrate here" area (2nd quadrant). CONCLUSION: The results showed that the priorities of patients and nurses did not match in terms of some of the rehabilitation nursing services. Thus, rehabilitation nursing services need to be provided based on the patients' needs. Allocation of resources for the service items that fell in the "concentrate here" area of the IPA need be reconsidered for the quality in nursing care.
Education ; Humans ; Nursing Care ; Nursing Services ; Rehabilitation Nursing* ; Rehabilitation* ; Research Design ; Resource Allocation

The antigen location of Cryptosporidium parvum, which stimulates antibody formation in humans and animals, was investigated using infected human sera. Immuno-electron microscopy revealed that antigenicity-inducing humoral immunity was located at various developmental stages of parasites, including asexual, sexual stages, and oocysts. The amount of antigen-stimulating IgG antibodies was particularly high on the oocyst wall. The sporozoite surface was shown to give stimulation on IgG and IgM antibody formation. Trophozoites implicated the lowest antigenicity to humoral immunity, both IgG and IgM, by showing the least amount of gold labeling. Immunogold labeling also provided clues that antigens were presented to the host-cell cytoplasm via feeder organelles and host-parasite junctions.
Animals ; Antibodies, Protozoan/*immunology ; Antigens, Protozoan/*analysis ; Cryptosporidium parvum/*chemistry/*immunology/ultrastructure ; Female ; Humans ; Immunoglobulin G/immunology ; Immunoglobulin M/immunology ; Mice ; Microscopy, Immunoelectron ; Sporozoites/chemistry/immunology/ultrastructure ; Staining and Labeling/methods ; Trophozoites/chemistry/immunology/ultrastructure

BACKGROUND: Surgical hepatic inflow obstructions such as the Pringle Maneuver (PM) or hepatic vascular exclusion (HVE) can reduce bleeding during hepatic resection, but ischemia/reperfusion injury of the liver and systemic hemodynamic changes are also inevitable during and after PM or HVE. Nitric oxide plays a pivotal role in ischemia/reperfusion injury. We evaluated hemodynamic changes and changes of nitric oxide during liver ischemia/reperfusion injury excluding the effects of intestinal ischemia. METHODS: Liver ischemia was induced by clamping of the portal triad, infrahepatic and suprahepatic inferior vena cava for 90 minutes. To exclude the effects of intestinal ischemia during liver ischemia, portal and iliac venous blood was bypassed to the jugular vein using a pump. Hemodynamic parameters and nitric oxide were measured serially; before and during ischemia, and after reperfusion. RESULTS: Mean arterial blood pressure (MAP) was well-maintained during ischemia, but after reperfusion, MAP, cardiac output (CO) and stroke volume (SV) significantly decreased (35 - 40, 30 - 40 and 30%, respectively) postischemia. Compared to preischemia, systemic vascular resistance and heart rate did not change after reperfusion. Pulmonary vascular resistance and mean pulmonary arterial blood pressure significantly increased (220 - 250% and 60 - 70%) after reperfusion. Nitric oxide (NO) did not change until 20 minutes after reperfusion, but after 40 minutes reperfusion, NO significantly decreased (20%) compared to preischemia. CONCLUSIONS: After 90 minutes warm liver ischemia/reperfusion causes hypotension induced by decreased CO and SV. Increased PVR seems to be the cause of decreased CO and SV. NO-SVR interaction does not seem to be the cause of postreperfusion hypotension.
Arterial Pressure ; Cardiac Output ; Constriction ; Heart Rate ; Hemodynamics* ; Hemorrhage ; Hypotension ; Ischemia ; Jugular Veins ; Liver* ; Nitric Oxide* ; Reperfusion ; Stroke Volume ; Vascular Resistance ; Vena Cava, Inferior

It was reported that the etiologies of recurrent spontaneous abortion are immunologic factors, endocrinologic problems, anatomical abnormalities, genetic abnormalities, infection, and unexplained factors. Among those etiologic factors, genetic abnormalities occur in about 5% of the couples who experience recurrent spontaneous abortions, and most common parental chromosomal abnormality contributing to recurrent abortion is balanced translocation. The advent of in vitro fertilization (IVF), the development of skills associated with the handling of human embryo, and an explosion of knowledge in molecular biology have opened the possibility of early diagnosis of genetic disease in preimplantation embryos. Therefore preimplantation genetic diagnosis (PGD) is indicated for couples, infertile or not, at risk of transmitting a genetic disease. A case of successful pregnancy and term delivery by PGD using fluorescence in situ hybridization (FISH) technique in patient with recurrent spontaneous abortion due to balanced translocation is presented with brief review of literatures.
Abortion, Habitual ; Abortion, Spontaneous* ; Blastocyst ; Chromosome Aberrations ; Early Diagnosis ; Embryonic Structures ; Explosions ; Family Characteristics ; Female ; Fertilization in Vitro ; Fluorescence ; Humans ; Immunologic Factors ; In Situ Hybridization ; Molecular Biology ; Parents ; Pregnancy* ; Preimplantation Diagnosis* ; Prostaglandins D

BACKGROUND: Immunohistochemical staining of skin for panaxonal marker, protein gene product 9.5 (PGP 9.5), has recently emerged as a useful diagnostic procedure for the assessment of small nerve fibers. The first aim of our study is to quantify the intraepidermal nerve fibers (IEDNF) and to investigate the histological changes of IEDNF in diabetic patents. And the second is to evaluate whether IEDNF has the correlation with the clinical, electrophysiological and biological parameters. METHODS: Skin biopsy specimens were obtained at the distal leg and proximal thigh from twelve type 2 diabetes mellitus patients having the symptoms of peripheral polyneuropathy. Fixed sections were stained using PGP 9.5, and the number of intraepidermal nerve fibers at each site was compared with those of fifteen normal healthy volunteers. We analyzed the correlation of IEDNF density with the clinical history, neuropathic symptom score (NSS), severity of diabetes (serum glucose, HbA1C), and nerve conduction studies. RESULTS: The number of IEDNF in diabetic patients was 3.0 per millimeter at the distal leg and 12.7 per millimeter at the proximal thigh compared with 15.3 per millimeter and 23.3 per millimeter in normal control respectively. Some specimen showed a morphological change of axons such as axonal swelling. The IEDNF density was not correlated with the duration of disease, biological or electrophysiological parameters but correlated with the clinical neuropathic symptom score. CONCLUSIONS: The IEDNF density is reduced in all the diabetic patients, more severely at the distal extremity. We suggest skin biopsy can provide the quantification as well as the objective evidence for the small fiber involvement of diabetic neuropathy.
Axons ; Biopsy* ; Diabetes Mellitus, Type 2 ; Diabetic Neuropathies* ; Erythromelalgia ; Extremities ; Glucose ; Healthy Volunteers ; Humans ; Leg ; Nerve Fibers* ; Neural Conduction ; Polyneuropathies ; Skin* ; Thigh

Malignant schwannomas arising from the peripheral nerve sheath of the foot are very rare. We encountered a case of malignant schwannoma of the great toe in a 60-year-old woman with painful swelling and exudative ulceration, and report the findings of MR imaging and review the literature.
Female ; Foot ; Humans ; Magnetic Resonance Imaging ; Middle Aged ; Neurilemmoma* ; Peripheral Nerves ; Toes* ; Ulcer