PURPOSE: This study was conducted to identify the influencing factors of job stress, self-efficacy, and organizational culture to presenteeism in clinical nurses. METHODS: A descriptive correlation research design was used for the this study. The subjects were 245 nurses working at the hospital in S, A and C City, from August 1st to October 30th 2014. Data were analyzed using t-test, ANOVA, Scheffe's test, stepwise multiple regression by SPSS 21.0 program. RESULTS: Job impairment indicated a significant positive relationship to job stress (p=.009), health problem (p<.001), and indicated significant negative relationship to self-efficacy (p<.001), innovative-oriented (p<.001), affiliative-oriented (p=.002), task-oriented (p=.026) in organizational culture. Significant factors of influencing to presenteeism were self-efficacy (p<.001, beta=-.363), culture of task-oriented (p<.001, beta=-.248) in organizational culture, and health problem (p=.002, beta=.187). CONCLUSION: Self-efficacy was defined as a variable to influence on presenteeism, and developing of strategies and program to strengthen self-efficacy and task-oriented of organizational culture in nursing is helpful to reduce the presenteeism of clinical nurses.
Nursing ; Organizational Culture ; Research Design

PURPOSE: The purpose of this study was to determine the current state of nursing intervention for maternal adaptation and its' effectiveness in Korea by utilizing a systematic review. METHODS: The PICO(Population-Intervention-Compar ator-Outcome) strategy was established, and 1,720 pieces of literature published during the last ten-year period from four electronic databases were reviewed. Eighteen references that met inclusion and exclusion criteria were finally selected for systematic review. The quality of references using critical appraisal checklist for experimental studies were evaluated, and then systematic review and meta-analysis were conducted. RESULTS: All 18 references were quasi-experimental research design. Most interventions were provided at the hospital and postpartum care center. Maternal adaptation interventions appeared to be of many types, and particularly maternal role education programs were the most common. Confidence in maternal role was used as the most common variable for the maternal adaptati on. Various interventions for helping maternal adaptation in the postnatal period improved maternal confidence, moth er-infant attachment, maternal satisfaction and mother-infant interaction effectively. CONCLUSION: A diversity of nursin g interventions in postnatal period improved various aspects of maternal adaptation. Randomized controlled trials and longitudinal studies are needed in order to verify the effect of interventions for maternal adaptation more clearly.
Checklist ; Electronics ; Electrons ; Humans ; Clinical Trial ; Korea ; Mothers ; Moths ; Postnatal Care ; Research Design

PURPOSE: To investigate the relationships among mother's perception of her own newborn, her caring-confidence level, and her child-rearing attitude; and to provide data for developing effective nursing education programs on maternal newborn care. METHOD: Explorative survey questionnaires were completed by 159 married mothers of newborns from November 2003 to March 2004. Data were analyzed using SPSS/Win 10.0 by t-test and Pearson's Correlation coefficient. RESULTS: The mean scores of the mother's perception of her own newborn, her caring-confidence level, and her child-rearing attitude were .26, 3.13, and 3.43 respectively. There was a positive correlation between mother's perception of her own newborn and her child-rearing attitude. There was a significant correlation between mothers caring-confidence level and her child-rearing attitude. Score of caring-confidence was significantly different depending on the availability of helper and history of delivery. CONCLUSION: Availability of helper and history of delivery significantly affected mothers caring-confidence. This in turn, along with mothers perception of her own newborn, enhanced mothers child-rearing attitude. Thus, an effective education for mothers should include these factors.
Education ; Education, Nursing ; Humans ; Infant, Newborn* ; Mothers* ; Child Health ; Surveys and Questionnaires

PURPOSE: This study was intended to investigate the types and seriousness of the couvade syndrome, pregnancy-related physical and psychological symptoms among expectant fathers whose spouses were pregnant. METHOD: The subject was consists of 100 expectant fathers at one hospital in Seoul, Korea. The pregnant women had not been diagnosed any medical complication. Data were analyzed by SPSS/PC program. RESULT: 1) The total mean score was 1.85: the mean score of perceived physical symptoms (1.87) revealed higher than the mean score of psychological symptoms (1.81). 2) With the respect to the general characteristics of subjects, there were statistically significant correlations between subject's level of education and couvade symptoms (r=-.209, p=.037), gestational age and couvade symptoms (r=-.227, p=.023), family total income and couvade symptoms (r=-.198, p=.048), perceived self health status and couvade symptoms (r=-.254, p=.011). 3) With the respect to the general characteristics of subjects, there were statistically significant differences in pregnant woman's age (t=1.363, p=.044),occupation of subject (F=3.594, p= .009), educational level of subject (t=3.506, p=.002), family total income (F=16.822, p= .000), perceived self health status (F=3.151, p=.047). CONCLUSION: Couvade syndrome is an issue for nurses who perform an important role in the care of pregnant women and their spouses.
Education ; Fathers ; Female ; Gestational Age ; Humans ; Korea ; Pregnant Women ; Seoul ; Spouses*

Herpes simplex esophagitis can occur in those with normal immune function, but is more often seen in those who are immunocompromised. In one series, 5 percent of post-kidney transplant recipients had herpes esophagitis. We experienced a case of herpes simplex esophagitis, following renal transplantation in a 9 year old male. He complained of epigastric pain, nausea and blood-tinged vomiting. Endoscopic examination showed volcano ulcer, mucosal friability and multiple confluent ulcers covered by whitish exudates on elevated margin in the middle and lower esophagus. Microscopic findings revealed multinucleated giant cells, margination of chromatin, intense nonspecific inflammation and strong positive for herpes simplex virus immunohistochemical staining. Esophageal lesions and symptoms improved after acyclovir therapy.
Acyclovir ; Child* ; Chromatin ; Esophagitis ; Esophagus ; Exudates and Transudates ; Giant Cells ; Herpes Simplex* ; Humans ; Inflammation ; Kidney Transplantation ; Male ; Nausea ; Simplexvirus* ; Transplantation ; Ulcer ; Vomiting

PURPOSE: To evaluate and compare the performance of shear-wave elastography (SWE) for breast masses using the local shear wave speed (m/sec) vs. Young modulus (kPa). METHODS: A total of 130 breast lesions in 123 women who underwent SWE before ultrasound-guided core needle biopsy or surgical excision were included. With the region-of-interest placed over the stiffest areas of the lesion on SWE, the quantitative mean, maximum, and standard deviation (SD) of the elasticity values were measured in kPa and m/sec for each lesion. The SD was also measured with the region-of-interest including the whole breast lesion (wSD). The area under the receiver operating characteristic curve (AUC), sensitivity, and specificity of each elasticity value measured in kPa and m/sec were compared. RESULTS: Of the 130 lesions, 49 (37.7%) were malignant and 81 (62.3%) were benign. The AUCs for the mean, maximum, and SD of the elasticity values using kPa and m/sec did not differ significantly: mean, 0.974 vs. 0.974; maximum, 0.960 vs. 0.976; SD, 0.916 vs. 0.916. However, the AUC for wSD showed a significant difference: 0.964 (kPa) vs. 0.960 (m/sec) (P=0.036). There was no significant difference in the sensitivity and specificity of the mean, maximum, and wSD of the elasticity values. However, the specificity of the SD was significantly different between the two different measurements: 95.1% (kPa) vs. 87.7% (m/sec) (P=0.031). CONCLUSION: The quantitative elasticity values measured in kPa and m/sec on SWE showed good diagnostic performance. The specificity of the SD and AUC of the wSD measured in kPa were significantly higher than those measured in m/sec.
Area Under Curve ; Biopsy, Large-Core Needle ; Breast* ; Elastic Modulus* ; Elasticity ; Elasticity Imaging Techniques* ; Female ; Humans ; ROC Curve ; Ultrasonography, Mammary

PURPOSE: To evaluate the value of breast MRI in analysis of papillomas of the breast. MATERIALS AND METHODS: From 1996 to 2004, 94 patients underwent surgery due to papillomas of the breast. Among them, 21 patients underwent 3D fast low angle shot (FLASH) dynamic breast MRI. Eight masses were palpable and 11 of 21 patients had nipple discharge. Two radiologists indifferently analyzed the location, size of the lesions and shape, margin of the masses, multiplicity and ductal relation. The MRI findings were categorized according to breast imaging reporting and data system (BI-RADS) lexicon. The amount and pattern of enhancement and associated findings were also evaluated according to BI-RADS. We then compared the MRI findings with galactography, mammography and breast ultrasonography (US) and examined histopathologic correlation. RESULTS: On breast MRI, the lesion size was 0.4-1.59 cm, and 18 patients showed subareolar location. On 4.25 cm (mean 1.54) dynamic enhanced images, imaging findings showed mass (n = 10), intracystic mass (n = 3), focus (n = 5), ductal enhancement (n = 2), and segmental enhancement (n = 1). In cases of the masses, the shapes of the masses were round (n = 4), lobulated (n = 3), and irregular (n = 6), and margins were circumscribed (n = 6), microlobulated (n = 5), and indistinct (n = 2). The enhancement patterns were homogeneous enhancement (n = 7), heterogeneous (n = 3) or rim enhancement (n = 3). CONCLUSION: The contrast enhanced dynamic breast MRI was highly sensitive for diagnosis of breast papillomas. MRI could play a key role in the pre-operative work-up for multiple papillomas and papillomatosis.
Adult ; Aged ; Breast Neoplasms/*diagnosis ; Female ; Humans ; Magnetic Resonance Imaging/*methods ; Middle Aged ; Papilloma, Intraductal/*diagnosis ; Sensitivity and Specificity

Vascular tumors of the breast are a rare disease. A hemangioma in the male breast is an extremely rare benign disease. We report a case of a 53-year-old-man with a capillary hemangioma of the breast.
Breast ; Capillaries ; Hemangioma ; Hemangioma, Capillary ; Humans ; Male ; Rare Diseases

Osteoarthritis (OA) is the most common arthritis which leads to chronic disability. Because patients usually present at medical care at an advanced stage of disease, research on pathogenesis of OA using human subjects is difficult. Therefore, animal models of OA are used extensively in search of pathogenesis of degenerative joint disease and in search of potential disease modifying anti-OA drugs. For induction of OA, chemical and surgical methods have been employed widely due to several advantages, such as faster onset of disease and reproducible induction of arthritic change. Intra-articular injection of a chemical such as monosodium iodoacetate or collagenase can cause the degeneration of cartilage and the development of osteoarthritis by inhibition of the activity of glyceraldehyde-3-phosphate dehydrogenase in chondrocytes or by induction of synovial inflammation and degeneration of supporting structure and resultant instability, respectively. Surgical induction involves destabilizing the knee joint by transection of the cranial cruciate ligament, collateral ligaments, or meniscotibial ligament with or without removing all or part of the meniscus. Surgical models are used not only in small animals but also in larger animals such as rabbits, sheep and dogs. Additionally, genetically modified mouse models offer opportunities to look into a specific role of a molecule or signaling pathway in the joint degradation. On the other hand, whether these models, chemically or surgically induced, or genetically modified, properly represent human OA is a critical question. Except for a limited number of cases, most human OA develops insidiously over decades without significant antecedent knee injury. In this sense, spontaneous model which develops in mice and guinea pigs might more closely resemble human OA. In this review, widely used animal models of OA are presented, focusing on the methods of its induction, their use for determining the pathophysiology of OA, and advantages and limitations of its use.
Animals ; Arthritis ; Cartilage ; Chondrocytes ; Collagenases ; Collateral Ligaments ; Dogs ; Guinea Pigs ; Hand ; Humans ; Inflammation ; Injections, Intra-Articular ; Joint Diseases ; Joints ; Knee Injuries ; Knee Joint ; Ligaments ; Mice ; Models, Anatomic ; Models, Animal ; Osteoarthritis ; Oxidoreductases ; Rabbits ; Sheep

PURPOSE: Diallyl disulfide (DADS) is a major organosulfur compound derived from garlic. It has been reported that DADS is able to inhibit the proliferation of several tumor cells. In this study, the effect of DADS was investigated in terms of the proliferation of AGS, gastric adenocarcinoma cell line at various concentrations. METHODS: The viability of cultured cells was determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide assay. To detect the induction of apoptosis, Annexin V-FITC/propodium iodide (PI) staining assay was performed. Analysis of reactive oxygen species (ROS) and the distribution of cells in the cell cycle were measured by a flow cytometer. And using the Western blot analysis, the change of Fas, caspase-3, Bax, Bcl-2 activity was measured. RESULTS: The percentage of live AGS cells was decreased to 23% of that in the control group after 400 microM DADS treatment for 48 hours. The Annexin V positive/PI negative (apoptosis portion) area increased from low concentration of DADS to high concentration. When comparing among the DADS treatment groups, the amount of ROS production increased in a dose dependent manner. The percentage of sub-diploid DNA content increased from 8.71% at 50 microM to 25.74% at 400 microM DADS treatment group. The expressions of Fas, caspase-3, Bax were increased and that of Bcl-2 was decreased in a dose dependent manner. CONCLUSION: DADS decreases the viability of AGS cell lines and induces apoptosis in a dose-dependent manner. But the relationship of the anti-proliferative effect of DADS and related molecular changes were not clearly proportional to the concentration of DADS.
4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid ; Adenocarcinoma ; Allyl Compounds ; Annexin A5 ; Apoptosis ; Blotting, Western ; Caspase 3 ; Cell Cycle ; Cell Line ; Cells, Cultured ; Disulfides ; DNA ; Garlic ; Reactive Oxygen Species ; Stomach Neoplasms