1.Two cases of theca cell tumor of the ovary.
Yong JOE ; Young Ho JUNG ; Eui Seon RO ; Yong Pil KIM ; Soon Uk KWON
Korean Journal of Obstetrics and Gynecology 1992;35(4):451-455
No abstract available.
Female
;
Ovary*
;
Theca Cells*
;
Thecoma*
2.Determination of antigenic domain in GST fused major surface protein (Nc-p43) of Neospora caninum.
Eui Sun SON ; Hye Jin AHN ; Jae Hoon KIM ; Dae Yong KIM ; Ho Woo NAM
The Korean Journal of Parasitology 2001;39(3):241-246
The antigenic domain of the major surface protein (Nc-p43) of Neospora caninum was examined by polymerase chain reaction of its gene fragments and recombinant expression as GST fusion proteins. The fragments of Nc-p43 were as follow: a total open reading frame (OFR), T; OFR without signal sequence and C-terminal hydrophobic sequence, S; N-terminal 2/3 parts of S, A; C-terminal 2/3 parts, P; N-terminal 1/3 part, X; middle 1/3 part, Y; and C-terminal 1/3 part, Z, respectively. The DNA fragments were cloned into pGEX-4T vector. Recombinant plasmids transformed into Escherichia coli of BL21 pLysS (DE3) strain were induced to express GST or GST fused fragments of Nc-p43 such as 69 kDa protein for T, 66 kDa for S, 52 kDa for A, 53 kDa for P, and 40 kDa proteins for X, Y, and Z, respectively in SDS-PAGE. The Nc-p43 fragments of T, S, and P reacted with a bovine serum of neosporosis while those of A, X, Y, and Z together with GST did not in the western blot. These findings suggest that the antigenic domain of Nc-p43 of N. caninum may be localized in the C-terminal 2/3 parts. Together with A19 clone in SAG1 of Toxoplasma gondii (Nam et al., 1996), the P fragment of Nc-p43 could be used as efficient antigens to diagnose and differentiate those infections with both species.
Amino Acid Sequence
;
Animals
;
Base Sequence
;
Biological Markers/analysis
;
Blotting, Western
;
Cells, Cultured
;
Cercopithecus aethiops
;
Coccidiosis/diagnosis
;
Neospora/*immunology
;
Protozoan Proteins/*analysis/genetics/immunology
;
Reverse Transcriptase Polymerase Chain Reaction
;
Support, Non-U.S. Gov't
;
Vero Cells/parasitology
3.Osteogenic Sarcoma following Irradiation for Retinoblastoma.
Jae Myung KIM ; Dong Ho YOUN ; Buk Won PAIK ; Yong Il KIM ; Eui Keun HAM
Journal of the Korean Ophthalmological Society 1967;8(3):37-41
A case of Osteogenic sarcoma arised from orbit 4 years after the radiation therapy for retinoblastoma in a 9 years old girl is presented. 4 Years ago, under the diagnosis of retinoblastoma, the left orbital exenteration was performed and was treated with x-ray radiation giving 4.500 gamma tumor dose in 4, weeks. On admission, the left orbital cavity was filled with hard mass and orbital bone revealed extensive destruction with osteoplastic changes on x-ray, and diffuse sarcomatous growth of anaplastic cells with abundant osteogenesis and osteoclastic activity microscopically. It is of authors' opinion that osteogenic sarcoma of orbital bone in this presented case might developed by irradition on retinoblastoma.
Child
;
Diagnosis
;
Female
;
Humans
;
Orbit
;
Osteoclasts
;
Osteogenesis
;
Osteosarcoma*
;
Retinoblastoma*
4.Posttraumatic Middle Cerebral Artery Occlusion: Case Report.
Eui Wha CHUNG ; Yong Don KIM ; Young Soo KIM
Journal of Korean Neurosurgical Society 1977;6(1):103-108
Although obstruction of the carotid artery after head trauma or non-penetrating injuries of the neck had been well known, reports of occlusion of middle cerebral artery following closed head trauma are rare. Up to now Jacque, et al, have found only 22 cases of posttraumatic middle cerebral artery occlusion including their own one case in the world literatures since DeVeer and Browder reported the first case in 1942. We report a case of posttraumatic middle cerebral artery occlusion. The patient developed right hemiplegia, aphasia and mental confusion 2 days following closed head trauma. Left cerotid angiograms revealed complete occlusion of the horizontal portion of the left middle cerebral artery distal to the origin of the lenticulostriate branches. Previously reported cases are review and possible pathophysiological mechanisms discussed.
Aphasia
;
Carotid Arteries
;
Craniocerebral Trauma
;
Head Injuries, Closed
;
Hemiplegia
;
Humans
;
Infarction, Middle Cerebral Artery*
;
Middle Cerebral Artery*
;
Neck
5.Postirradiation Extraskeletal Osteosarcoma (A case associated with aggressive fibromatosis).
Hy Min KIM ; Je Geun CHI ; Yong Il KIM ; Eui Keun HAM
Korean Journal of Pathology 1987;21(2):98-101
A case of postirradiation extraskeletal osteosarcoma with aggressive fibromatosis of the overlying soft tissue of radiation field is reported in a 57 year old house wife who was treated with operation and radiation therapy for cervix carcinoma of the uterus 23 years ago. The overlying aggressive fibromatosis showed characteristic radiation angiitis and atrophic vascular changes such as hyaline degeneration and obliteration of the capillaries which were highly campatible with radiation changes. She also had multiple osteogenic sarcoma in pelvic cavity, occurring in the mesentery bed. As for the histogenesis in this case, we thought the possiblity that fibroblasts went through a process of differentiation into osteoblasts that were responsible for bone formation in the process of malignant change of the aggressive fibromatosis.
6.Krukenberg Tumor: Clinico-pathologic analysis of 36 cases.
Yeon Lim SUH ; Geung Hwan AHN ; Yong Il KIM ; Eui Keun HAM
Korean Journal of Pathology 1985;19(3):305-312
A total of 36 typical Krukenberg tumors of the ovary was obtained from the pathology file of the Department of Pathology, College of Medicine, Seoul National University during a period of 17 years from January 1968 to December 1984. By definition, all were characterized by the presence of mucin containg signet ring cells within the cellular, nonneoplastic ovarian stroma. The clinico-pathologic characteristics of 36 Krukenberg tumors were as follow: The Krukenberg tumors accounted for 16.3% of all ovarian malignancies. The age of the patient at the time of diagnosis of the Krukenberg tumor ranged from 28 to 69 years with an average of 43 years. A primary carcinoma of stomach (31 cases) of colon (1 case) was found in 32 (88.9%) of 36 patients. The primary carcinomas was not detected in four cases, and autopsy was not performed in any case. In 22 cases the primary carcinomas had been diagnosed before ovarian tumors were found. The ovarian and the primary carcinomas were identified synchronously in 6 cases, while in 8 cases the primary carcinomas were not discovered until after the ovarian tumors had been treated. The gross diameter of the ovarian tumor ranged from 1.5cm to 28cm with an average of 10.3cm. The largest weighed 4,550gm. The Krukenberg tumors typically formed rounded or reniform, solid mass that were coarsely lobulated or bosselated. The cut surface was yellow white and associated frequently with nodular, myxoid or gelatinous area and cystic changes of various size. Both ovaries were involved in 29(80.6%) of the cases and one ovary in 7(19.4%). Krukenberg tumors classified into the three major types on the basis of the characteristic morphologic patterns of signet ring cells. The first type was classic Krukenberg tumor(28 cases) represented by predominent components of typical signet ring cells. The second type was tubular Krukenberg tumor(5 cases) characterized by tubular structures resembling a Sertoli-Leydig cell tumor. The third type was re tiform Krukenberg tumor (3 cases) characterized by an irregular network of elongated, often slitlike tubules and cysts, which resembled the rete testis.
7.Morphology and topography of the lingual nerve in Koreans.
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2001;27(2):118-128
Two major salivary glands, submandibular duct, lingual nerve, and vessels are situated beneath the mouth floor. Among these, passing through the pterygomandibular space, lingual nerve is innervated to the lingual gingiva and the mucosa of mouth floor, and is responsible for the general sensation of the anterior two thirds of the tongue. So, the injury of the lingual nerve during an anesthesia or surgery in the retromolar area may cause complications such as a numbness, a loss of taste of the tongue and the other dysfunctions. Therefore, to find out the morphology and the course of lingual nerve and to clarify the topographical relationships of lingual nerve at the infratemporal fossa and paralingual space area, 32 Korean hemi-sectioned heads were dissected macroscopically and microscopically with a viewpoint of clinical aspect in this study. This study demonstrated various anatomical characteristics with relation to the course and topography of the lingual nerve in Koreans. And clinical significances based on the anatomical variations through the topography of the courses and communications between the mandibular nerve branches were described in details.
Anesthesia
;
Chorda Tympani Nerve
;
Gingiva
;
Head
;
Hypesthesia
;
Lingual Nerve*
;
Mandibular Nerve
;
Mouth Floor
;
Mucous Membrane
;
Salivary Glands
;
Sensation
;
Tongue
8.Pathological Analysis of the Basal Cell Carcinoma.
Kye Yong SONG ; Young Hwa CHOI ; Mi Kyung KIM ; Kenn Kook LEE ; Eui Kenn HAM
Korean Journal of Pathology 1994;28(2):160-167
Though basal cell carcinoma is the most frequent and increasing malignant tumor of the skin in Korea, its pathological analysis has been done only on the small numbers. So, we did a comprehensive pathologic study on the 283 patients with basal cell carcinoma diagnosed in the Department of Pathology, Seoul National(233cases) and Chung-Ang(50cases) University Hospital during 1975-1992. The age distribution was ranged from 15 to 84 years with highest incidence rate in the age group of 5th-8th decades and 83.7% of all patients were over 40 years of age. Sex difference was not noted. The most common site was face occuring in 235 out of 283cases(83.0%) especially in the eyelid(25.5%), nose(17.9%) and cheek(16.6%). The most frequent histopathologic type was solid type(54.0%) followed by mixed(23.9%), adenoid(7.5%), and metatypical(4.7%). Among 51 mixed type, all showed solid components with adenoid(51.0%) followed by morphea(25.5%) and metatypical type(13.7%). And among 14 recurrent cases, solid type is found in 50% of cases. The characteristic clinicopathological findings are solid arrangement of tumor cells with various histological pattern and predominant occurence on the face.
Incidence
9.Tinea Corporis Occurring in One ramily Caused by Trichophyton verrucosum.
Yong Dae KIM ; Eui Soo PARK ; Kyu Suk LEE ; Joon Young SONG
Korean Journal of Dermatology 1989;27(4):435-439
We report a case of tinea corporis occurring in one family caused by Trichophyton verrucosum. Father, mother and a son in a family had well defined scaly erythematous patches on the forearm, cheek and postauricular area. Histopathologically fungal hyphae were found in the horny layer of the epidermis in PAS stained sections. In mycological study, charact,eristic feature of T. verrucosum were found. The possible source of the infections was the cattle that they raised in their house. After eight weeks administration of ketoconazole, the lesions were healed leaving slight brownish discoloration.
Animals
;
Cattle
;
Cheek
;
Epidermis
;
Fathers
;
Forearm
;
Humans
;
Hyphae
;
Ketoconazole
;
Mothers
;
Tinea*
;
Trichophyton*
10.A clinical study on attempted suicide with drug in the rural area.
Mong Ha PARK ; Yong Kyun ROH ; Jae Hweon KIM ; Eui Jung HWANG ; Myung Ho HONG
Journal of the Korean Academy of Family Medicine 1991;12(1):22-29
No abstract available.
Suicide, Attempted*