We studied the usefulness of prostate specific antigen (PSA) as well as prostatic acid phosphatase (PAP) as marker of prostatic cancer in twelve cases of advanced prostatic cancer including 4 or stage C and 8 of stage D, 50 cases of benign prostatic hyperplasia (BPH) and 50 cases of nonprostatic diseases as normal control. The positive rates of PSA were 100% for prostatic cancer, 20% for BPH and O% for nonprostatic diseases, and those of PAP were 75% for prostate cancer, 8% for BPH and 2% for nonprostatic diseases. These results indicated hat PSA is more sensitive than PAP but less specific than PAP in diagnosis of prostatic cancer. Serum PSP level was correlated with the weight of prostate in BPH patients. Serum PSA level determined during the follow-up after endocrine therapy for prostatic cancer reflected the clinical course of the patients. Because of its relatively low specificity, PSA alone may not be useful for early diagnosis of prostatic cancer. If in combination with other diagnostic modalities, it may be useful in early diagnosis and therapeutic monitoring of prostatic cancer within restricted limits.
Acid Phosphatase ; Diagnosis ; Early Diagnosis ; Follow-Up Studies ; Humans ; Prostate* ; Prostate-Specific Antigen* ; Prostatic Hyperplasia ; Prostatic Neoplasms ; Sensitivity and Specificity

No Abstract Available.
Arthroplasty* ; Congenital Abnormalities* ; Humans ; Knee*

PURPOSE: To investigate postoperative incidence of complications and functional results between two groups, primary bipolar hemiarthroplasty and internal fixation with compression hip screw on unstable intertrochanteric fractures of the femur with severe osteoporosis in elderly patients. MATERIALS AND METHODS: 78 cases treated under unstable intertrochanteric fractures of the femur with severe osteoporotic elderly patients from March 1997 to August 2001 who have been followed up for more than a year were evaluated retrospectively between the group of bipolar hemiarthroplasty, 38 cases out of 60 cases and group of compression hip screw, 40 cases out of 59 cases. The incidence of complications and functional ability according to Merle d'Aubigne scale and the mortality rate were compared using student t-test. RESULTS: The means of Merle d'Aubigne scale for the hemiarthroplasty group and the compression hip screw group were at the last follow up, 15.0 and 13.6 respectively. The differences were statistically significant (p=0.04). Bipolar group revealed significant differences in general (18%) and mechanical complications (5%) between two groups (p<0.05). The mortality rates were 28% and 22% respectively and there were no significant differences statistically (p>0.05). CONCLUSION: We consider that primary bipolar hemiarthroplasty would be better method in the treatment of the unstable femoral intertrochanteric fracture with severe osteoporosis but we need much longer follow up.
Aged* ; Femur* ; Follow-Up Studies ; Hemiarthroplasty* ; Hip Fractures* ; Hip* ; Humans ; Incidence ; Mortality ; Osteoporosis ; Retrospective Studies

BACKGROUND: The persistence of infection by high-risk human papillomavirus (HPV) may lead to cervical cancer. Recently, the American Society for Colposcopy and Cervical Pathology (ASCCP) announced that oncogenic HPV screening and the PAP smear are the main methods of screening for cervical cancer. The goal of this study was to investigate the prevalence and genotyping of HPV, as well as the risk of cervical dysplasia. METHODS: HPV genotyping was conducted by a commercial chip assay. Cervical dysplasia was retrospectively reviewed using electronic medical records. The study participants were grouped together according to cervical dysplasia status: 'no dysplasia,' 'atypical squamous cells of undetermined significance (ASCUS),' 'low-grade squamous intraepithelial lesion (LSIL),' and 'high-grade squamous intraepithelial lesion (HSIL).' The HPV prevalence and genotyping were analyzed according to the cervical dysplasia group. RESULTS: The overall prevalence of HPV was 17.6% (91 out of 518 patients). HPV-18 (2.3%), HPV-16 (2.1%), and HPV-58 (1.2%) were the three most frequent genotypes. The prevalence of HPV infection and the high-risk HPV positive rate was higher in the ASCUS, LSIL, and HSIL groups than in the no dysplasia group (P<0.05). CONCLUSION: In this study, basic data regarding the prevalence and distribution of HPV genotypes were obtained. Since HPV vaccination has been actively encouraged among Korean women, a change in the prevalence of HPV and cervical dysplasia is expected in the future. This study provided basic data describing the prevalence of HPV and its genotypes in the pre-HPV vaccination era.
Colposcopy ; Electronic Health Records ; Female ; Genotype ; Human papillomavirus 16 ; Human papillomavirus 18 ; Humans ; Mass Screening ; Papillomavirus Infections ; Prevalence ; Retrospective Studies ; Uterine Cervical Neoplasms ; Vaccination