No abstract available.
Mortality*

No abstract available.
Amylases* ; Child* ; Encephalitis, Arbovirus* ; Humans

Nonfunctioning carcinoma of adrenal cortex is a rare disease and approximately 120 patients with nonfunctional adrenal cortical carcinoma have been reported in the world literature since first description of Rolienston and Marks in 1898. We report a case of nonfunctioning adrenal cortical carcinoma in a 47-year-old female patient, which was suspected by clinical investigation and confirmed by exploration and microscopic examination.
Adrenal Cortex* ; Adrenocortical Carcinoma ; Female ; Humans ; Middle Aged ; Rare Diseases

Nonfunctioning carcinoma of adrenal cortex is a rare disease and approximately 120 patients with nonfunctional adrenal cortical carcinoma have been reported in the world literature since first description of Rolienston and Marks in 1898. We report a case of nonfunctioning adrenal cortical carcinoma in a 47-year-old female patient, which was suspected by clinical investigation and confirmed by exploration and microscopic examination.
Adrenal Cortex* ; Adrenocortical Carcinoma ; Female ; Humans ; Middle Aged ; Rare Diseases

No abstract available.
Follow-Up Studies* ; Hydronephrosis*

Metastatic tumors of the epididymis are rare and only 10 cases were reported. The primary tumor sites were kidney, stomach, prostate, ileum, sigmoid colon and pancreas. We recently observed a case of metastatic carcinoma to the epididymis from a primary cancer in the sigmoid and transverse colon.
Colon, Sigmoid ; Colon, Transverse ; Cryptorchidism* ; Epididymis* ; Ileum ; Kidney ; Male ; Pancreas ; Prostate ; Stomach

Primary diffuse leptomeningeal gliomatosis (PDLG) is a rare condition with a fatal outcome, characterized by diffuse infiltration of the leptomeninges by neoplastic glial cells without evidence of primary tumor in the brain or spinal cord parenchyma. In particular, PDLG histologically diagnosed as gliosarcoma is extremely rare, with only 2 cases reported to date. We report a case of primary diffuse leptomeningeal gliosarcomatosis. A 68-year-old man presented with fever, chilling, headache, and a brief episode of mental deterioration. Initial T1-weighted post-contrast brain magnetic resonance imaging (MRI) showed diffuse leptomeningeal enhancement without a definite intraparenchymal lesion. Based on clinical and imaging findings, antiviral treatment was initiated. Despite the treatment, the patient's neurologic symptoms and mental status progressively deteriorated and follow-up MRI showed rapid progression of the disease. A meningeal biopsy revealed gliosarcoma and was conclusive for the diagnosis of primary diffuse leptomeningeal gliosarcomatosis. We suggest the inclusion of PDLG in the potential differential diagnosis of patients who present with nonspecific neurologic symptoms in the presence of leptomeningeal involvement on MRI.
Aged ; Biopsy ; Brain ; Diagnosis ; Diagnosis, Differential ; Fatal Outcome ; Fever ; Follow-Up Studies ; Gliosarcoma ; Headache ; Humans ; Magnetic Resonance Imaging ; Meningeal Carcinomatosis ; Meningoencephalitis ; Neuroglia ; Neurologic Manifestations ; Spinal Cord

PURPOSE: To analyse the expression of the p53 tumour suppressor gene in the synovial tissue from rheumatoid patients. Material and Methods : Synovial membranes were obtained from 13 patients diagnosed as having RA, and 9 osteoarthritis (OA) patients. We studied p53 expression by immunohistochemical analysis and p53 DNA sequence using direct DNA preparation method. RESULT: In immunohistological studies, the Do-1 monoclonal antibody stained at 6 specimens out of the 13 rheumatoid arthritis tissue biopsies analysed. There was no p53 mutation in osteoarthritis samples, but there were 4 p53 mutations from the 13 rheumatoid arthritis samples. p53 mutations were found at the codon 177 (CTG to CTA, GA), 277 (TGT to TGC, TC), and, two patients at the codon 237 (CAT to TAT, CT). CONCLUSION: The predicted amino acid substitutions in p53 were similar to those commonly observed in a variety of tumors and might influence growth and survival of rheumatoid synoviocytes.
Amino Acid Substitution ; Arthritis, Rheumatoid* ; Base Sequence ; Biopsy ; Codon ; DNA ; Genes, Suppressor ; Genes, Tumor Suppressor* ; Humans ; Immunohistochemistry ; Membranes ; Osteoarthritis ; Synovial Membrane*

Endometriosis is defined as an extrauterine growth of endometrial tissue and it is primarily limited in the pelvis but it can also occur in the pleural cavity as well as pulmonary parenchyme. The diagnosis of pulmonary endometriosis is usually based on the clinical history of recurrent hemoptysis in association with menstrual cycle and by histopathologic confirmation of endometrial tissue in the lung parenchyme. Pulmonary endometriosis was first reported by Lattes in 1956, and dozens of cases have been reported so far. We experienced a case of 25 year old single woman with a history of hemoptysis in association with her menstruation. The bleeding focus was localized with chest CT scan and repeated fibrooptic bronchoscopy and basal segmentectomy of the right lower lobe was performed. The resected specimen shows endometrial stroma and glands of early proliferative phase with respiratory epithelium on the laterobasal bronchus. Her postoperative course was uneventful with no recurrence of hemoptysis during 6 months of follow-up in the outpatient clinic.
Adult ; Ambulatory Care Facilities ; Bronchi ; Bronchoscopy ; Diagnosis ; Endometriosis* ; Female ; Follow-Up Studies ; Hemoptysis ; Hemorrhage ; Humans ; Lung ; Mastectomy, Segmental ; Menstrual Cycle ; Menstruation ; Pelvis ; Pleural Cavity ; Recurrence ; Respiratory Mucosa ; Tomography, X-Ray Computed

We report the first case of severe fever with thrombocytopenia syndrome (SFTS) and a spontaneous acute subdural hematoma (SDH) in Korea. A 79-year-old male presented with fever and thrombocytopenia. On the third day of hospitalization, his mental changed from drowsy to semi-coma. Brain computed tomography indicated an acute subdural hemorrhage on the right convexity. He was given early decompressive craniectomy, but did not survive. Real-time reverse transcription polymerase chain reaction analysis of a blood sample indicated the presence of SFTS virus (SFTSV). This is the first reported case with intracranial hemorrhage and SFTS. This case report describes our treatment of a patient with acute SDH and an infection from a tick-borne species of Bunyaviridae.
Aged ; Brain ; Bunyaviridae ; Decompressive Craniectomy ; Fever* ; Hematoma, Subdural* ; Hematoma, Subdural, Acute ; Hospitalization ; Humans ; Intracranial Hemorrhages ; Korea ; Male ; Orthobunyavirus ; Polymerase Chain Reaction ; Reverse Transcription ; Thrombocytopenia* ; Ticks*