2.A clinical study with pirarubicin in the advanced breast cancer.
Seung Taek OH ; Sang Sul JUNG ; Jong Tae SHIN ; In Chul KIM ; Eui Dong KIM
Journal of the Korean Cancer Association 1993;25(6):935-940
No abstract available.
Breast Neoplasms*
;
Breast*
3.Communicable Disease Surveillance System and Sentinel Surveillance.
Korean Journal of Epidemiology 1997;19(1):14-21
Surveillance is the ongoing and systematic collection, analysis of disease related data and dissemination of the information to the people who need it, and application of it to disease prevention and control. So, it is composed of reportable disease; system of data collection, analysis, distribution; coorporation of medical institution with public health organization and effective control. The most dynamic and important part of surveillance is the feedback mechanism. As for positive ways of feedback, there are dissemination of collected and analysed information and reimbursement to the reporters. Legal punishment is the negative way of feedback. The common systems that the developed countries use for communicable disease surveillance are notifiable disease surveillance, sentinel surveillance, and laboratory surveillance systems. Notifiable disease surveillance is for the diseases that their impact is serious to the community when epidemic occurs even though the number of cases is small. Most countries have this type of surveillance, but they suffer from low reporting rate. Sentinel surveillance is for the disease which is mild or whose trend is to be traced for the evaluation of the public health programs. Sampled reporters notifies the disease information voluntarily not by law. Laboratory surveillance is to support the notifiable and sentinel surveillance. It provides laboratory information on the microorganism and antibody level of the disease. Surveillance of communicable diseases in Korea is totally dependent on the notifiable disease reporting system, and there are many problems involved. To improve the surveillance of communicable diseases, it is strongly recommended that the sentinel and laboratory surveillance systems be adopted.
Communicable Diseases*
;
Data Collection
;
Developed Countries
;
Jurisprudence
;
Korea
;
Public Health
;
Punishment
;
Sentinel Surveillance*
4.Incidence of Parasites in Seoul Area Based on An Examination of the Severance Hospital Out-Patients.
Chin Thack SOH ; Keun Tae LEE ; Eui Woong SHIN ; Tae Chul KANG
Yonsei Medical Journal 1961;2(1):31-41
Of 14,682 samples of feces examined, 81.7% were positive for intestinal helminths. Trichocephalus trichiurus was observed most frequently, in 73.2%. Eight other species of helminths found were Ascaris lumbricoides, Hookworm, Trichostrongylus orientalis, Clonorchis sinensis, Tapeworm, Hymenolepis nana, Paragoniumus westermani and Enterobius vermicularis, listed in decreasing order. Double infections were found more frequently than single infections, and mixed infection of five or more species of helminths occurred in 0.2% Of 10,320 samples of feces examined, 22.3% were positive for intestinal protozoa, Entamoeba coli was observed most frequently, in 11.1%. Six other species, Endolimax nana, Giardia lamblia, Entamoeba histolytica, Iodamoeba butschlii, Chilomastix mesnill and lsospora hominis were found, in the order. It was noticed that E. histolytica was found more frequently in trichurial infection than with other helminths. Of 1,050 samples of sputum from the T. B. Clinic, 7.0% were positive for paragonimus eggs. Trichomonas vaginalis were found in 35.8%of 1,146 vaginal swabs examined. Seven cases of Plasmodium vivax infection were found among 140 suspected blood smears.
Incidence
5.A Case of Treatment of Acute Renal Failure due to Bilateral Ureter Injuries after Bilateral Inguinal Herniorrhaphy.
In Sun HWANG ; Eun Mi KIM ; Sang Mann SHIN ; Chul MOON ; Min Eui KIM
Korean Journal of Nephrology 1997;16(1):142-145
Inguinal herniorrhaphy is the most frequent general surgical operation performed by pediatric surgeons, but some complications can usually be attributed to inappropriate approach and traumatic dissection. We experienced a case of acute renal failure due to bilateral ureter injuries after bilateral inguinal hernia repairs. The patient was a 3 month old male infant who presented as anuria and generalized edema after bilateral herniorrhaphy and was treated with peritoneal dialysis for 2 weeks. After 4 days of peritoneal dialysis, general conditions and symptoms were improved, but anuria persisted for 2 weeks. We performed IVP and abdominal CT. Both studies showed abnormal dye accumulation in peritoneal cavity. Ureteroneocystostomy on right and segmental resection of ureter and end to end anastomosis of left ureter were done without any complications. He has been doing well and has had normal kidney function. Therefore we report a case of acute renal failure due to bilateral ureter injuries after both inguinal herniorrhaphy with a brief review of literatures.
Acute Kidney Injury*
;
Anuria
;
Edema
;
Hernia, Inguinal
;
Herniorrhaphy*
;
Humans
;
Infant
;
Kidney
;
Male
;
Peritoneal Cavity
;
Peritoneal Dialysis
;
Tomography, X-Ray Computed
;
Ureter*
6.Effect of Repeated Intracameral Injections of 1% Lidocaine on the Corneal Endothelium.
Ki Chul SHIN ; Eui Sang CHUNG ; Won Ryang WEE ; Young Suk YU ; Jin Hak LEE ; Dong Leen CHANG
Journal of the Korean Ophthalmological Society 2000;41(12):2645-2651
No Abstract Available.
Endothelium, Corneal*
;
Lidocaine*
7.A Statistical Standard for Detecting Epidemic of Notifiable Acute Communicable Diseases in Korea.
Yong Gyu PARK ; Eui Chul SHIN ; Kwang Ho MENG
Korean Journal of Epidemiology 1997;19(1):73-80
Many problems have been stated in the surveillance system of notifiable acute communicable diseases in Korea. Lack of objective tools for detecting epidemic is one of the most fundamental. We propose a statistical standard for detecting epidemic of those diseases that could be easily and promptly applicable to the existing data. Suggested standard measure is computed from the median and the spread of upper and lower hinge(spr(H)) which is robust to the assumption of normal distribution, so frequently used in exploratory data analysis as a measure of variation, and the results are compared with those of existing method using recent 3 years from January 1994 to December 1996 of monthly data of 8 notifiable acute communicable diseases in Korea. Monthly pattern of statistical epidemic between the proposed (median) and existing(mean) methods is similar. Therefore, we propose that the statistical epidemic should be defined when the current occurrence exeeds the standards of both methods. When the data collection is made weekly than monthly, the proposed method of determining the time of epidemic will be much helpful for the management of notifiable diseases.
Communicable Diseases*
;
Data Collection
;
Korea*
;
Statistics as Topic
8.Molecular cloning and characterization of peroxiredoxin from Toxoplasma gondii.
Eui Sun SON ; Kyoung Ju SONG ; Jong Chul SHIN ; Ho Woo NAM
The Korean Journal of Parasitology 2001;39(2):133-141
A cDNA of 1.1 kb comprising the gene encoding the peroxiredoxin of Toxoplasma gondii (TgPrx) has been cloned. The open reading frame of 591 bp was translated into a protein of 196 amino acids with a molecular mass of 25 kDa. Conserved 2 cysteine domains of Phe-Val-Cys-Pro and Glu-Val-Cys-Pro indicated TgPrx belonged to 2-Cys Prx families. TgPrx showed the highest homology with that of Arabidopsis thaliana by 53.9% followed by Entamoeba histolytica with 39.5% by the amino acid sequence alignment. Polyclonal antibody against recombinant TgPrx detected 25 kDa band in T. gondii without binding to host cell proteins. TgPrx was located in the cytoplasm of T. gondii extracellularly or intracellularly by immunofluorescence assay. The expression of TgPrx was increased as early as 30 min after the treatment with artemisinin in the intracellular stage, while no changes in those of host Prx I and TgSOD. This result implies that TgPrx may function as an antioxidant protecting the cell from the attack of reactive oxygen intermediates. It is also suggested that TgPrx is a possible target of chemotherapy.
Amino Acid Sequence
;
Animals
;
Antioxidants
;
*Artemisinins
;
Base Sequence
;
*Cloning, Molecular
;
Cysteine/metabolism
;
Molecular Sequence Data
;
Nucleic Acid Amplification Techniques
;
Peroxidases/chemistry/*genetics/physiology
;
Sesquiterpenes/pharmacology
;
Support, Non-U.S. Gov't
;
Toxoplasma/*enzymology
9.A case of Primary Transitional Cell Carcinoma of Ureteral Stump Following nephreetomy for renal tuberculosis.
Won Jae YANG ; Woong Kyu HAN ; Ju Eui HONG ; Tae Woong NOH ; Hong Hwan SHIN ; Seong Kyoo CHOI ; Seung Chul YANG
Korean Journal of Urology 2000;41(4):584-586
No abstract available.
Carcinoma, Transitional Cell*
;
Tuberculosis, Renal*
;
Ureter*
10.Ventriculoureteral Shunt Operation for Treatment of Recurrent Abdominal Pseudocyst Complicating Ventriculoperitoneal Shunt: Case Report and Technical Note.
Ryoong HUH ; Won Han SHIN ; Kyu LEE ; Soon Kwan CHOI ; Bark Jang BYUN ; Min Eui KIM ; Chul MOON ; In Soo LEE
Journal of Korean Neurosurgical Society 1993;22(5):666-671
We report a case of ventriculoureteral shunt to reise malfunctioning ventriculoperitoneal shunt in a 30-year-old man. The patient had 4 times recurrent pseudocyst filled with cerebrospinal fluid caused by complications at the distal end of the abdominal catheter. The presence of an abdominal pseudocyst can be detected by performing an ultrasound examination of the abdomen. We shall describe the operative technique of the ventriculoureteral shunt procedure without nephrectomy by reimplantation of the ureter and a psoas hitch.
Abdomen
;
Adult
;
Catheters
;
Cerebrospinal Fluid
;
Humans
;
Nephrectomy
;
Replantation
;
Ultrasonography
;
Ureter
;
Ventriculoperitoneal Shunt*