The neuromuacular blocking effects of the repeated bolus injection and continuous injection of vecuronium have been compared in 20 patients by means of evoked twitch tension. Group I received a loading dose (0.08 mg/kg) of vecuronium and followed by maintenance doae (0.02 mg/kg) when twitch tension had recovered to 25% of control. Group II received a loading doses (0. 08mg/kg) of vecuronium plus a continuous infusion delivering 0.06 mg/kg/hr. Anesthesia was maintained with nitrous oxide, oxygen and 1.5% enflurane. The neuromuscular blocking effect were reversed by the neostigmine 1.0 mg and robinul 0.2 mg when twitch tension had recovered 25% control in both groups near the end of operation. With repeated injection of vecuronium (group I), the duration of blockade of 25% recovery was 21.6+/-4.2 minutes and the recovery times from 25% to 75% was 6.8+/-1.9 minutes The continuous infusion of vecuronium (group II) produced consistent neuromuscular blockade at the average level of 90% twitch depression. The times from the end of infusion to 25% and fr,om 25% to 75% are averaged 16.0+/-2.5 and 4.2+/-0.7 minutes respectively. The reeovery index was more rapid in infusion group than maintenance group (P<0.05).
Anesthesia ; Depression ; Enflurane ; Humans ; Neostigmine ; Neuromuscular Blockade ; Nitrous Oxide ; Oxygen ; Vecuronium Bromide*

Juvenile xanthogranuloma is a congenital or perinatal tumor, 1 to 2 cm in diameter, usually located on the head. The extracutaneous lesions can occur on the eye, the lung, the epicardium, the oral cavity or the testicles. Subcutaneous form of juvenile xanthogranuloma has been reported very rarely in the literature. We report a unique case of a subcutaneous juvenile xanthogranuloma that showed 4 × 4 cm sized plaque and located on the extremity of 9-year-old girl.
Child ; Extremities ; Female ; Head ; Humans ; Lung ; Mouth ; Pericardium ; Testis ; Xanthogranuloma, Juvenile*

No abstract available.

Regenerative medicine (RM) aims to replace or regenerate human cells, tissues, or organs to restore or establish the normal function. RM comprises cells, biomaterials for scaffolds, and growth factors. The cells play an important role in regenerative medicine. Biomaterials can form tissue and transmit biological activity signals and promote cell adhesion. The biological growth factor is a signal transmitter necessary to regenerate tissues and organs. Bioprinting as a powerful tool for building tissue and organ structures in the field of tissue engineering has attracted enormous attention as a fabrication methodology for producing 3-dimensional structures. Bioprinting technology will be needed to treat musculoskeletal diseases. This paper will provide information that can be used as a regenerative medicine treatment for musculoskeletal diseases. It will enable the regeneration of the musculoskeletal system consisting of bones, joints, muscles, and nerves.

A 2-year-old girl had variably-sized, relatively well demarcated, depressed brownish patches on the left shoulder, back, and both legs from the age of 1 month. The biopsy specimen from the left shoulder showed an increase in the number of normal intradermal eccrine ducts and coils, which was compatible with pure eccrine nevus. The clinical manifestation of our case, including brownish depressed patches, was unique compared to other reported cases.
Back ; Biopsy ; Case Report ; Child, Preschool ; Female ; Human ; Leg ; Nevus/pathology* ; Shoulder ; Sweat Gland Neoplasms/pathology*

No abstract available.
Arteries* ; Cardiomyopathy, Hypertrophic* ; Humans ; Infant* ; Mothers*

Review of renal cell carcinoma was made on 28 cases admitted to Dept. of Urology during the period of 11 years from September 1, 1972 through September 30, 1983. 1. There were 17 males and females (ratio of 1.5:1) ranged in age from 19 to 69 years with peak incidence in the 6th decade. 2. The most common symptom and sign was hematuria in 75% but the classic triad of this tumor was present in 29%. 3. The abnormal laboratory findings were elevated ESR in 75%, anemia in 64%, and reversed A/G ratio without hepatic metastasis in 14%. 4. On the urogram renal mass was found in 50%, calyceal destruction in 48%, and nonvisualization of kidney in 39%. 5. The renal angiogram of 10 cases demonstrate hypervascularity in 7 cases, hypovascularity in 1 case, and tumor staining in 7 cases. 6. Staging of the tumor revealed stage in 13 cases, stage III in 5 cases, and stage IV in 7 cases. 7. The histological type revealed clear cell in 20 cases, granular cell in 1 case, and mixed cell in 7 cases. 8. Treatments were simple nephrectomy in 16 cases, simple nephrectomy with adjuvant therapy in 3 cases, and radical nephrectomy with adjuvant therapy in 5 cases.
Anemia ; Carcinoma, Renal Cell* ; Female ; Hematuria ; Humans ; Incidence ; Kidney ; Male ; Neoplasm Metastasis ; Nephrectomy ; Urology

Trichomoniasis, a common and sometimes distressing condition in women, is caused by infection of the genitourinary tract by the pathogenic protozoan Trichomonris aginalis(T. vaginalis). Men may also be infected, although frequently without any symptoms, and most cases of trichomoniasis are sexually transmitted. The best evidence for an etiologic role for T. vaginalis is in nongonococcal urethritis(NGU). In epidemiologic studies, T,ginalis has been isolated from 1 to 68 percent in men with NGU. The nurnber of NGU is increasing rapidly than gonorrhea in deeloped nations, and in some developing countries, especially in Korea, In view of the difficulties in findng trichomonads by direct microsco by in men, urine culture and serodiagnosis plays an important role in the diagnostic work. Urine culture, indirect fluorescent antibody test(IFAT) and enzyme-linked immunosorbent assay (ELISA) were used to elecect T.vaginalis in 221 patients with male NGU. These patients visited the VD Clinic of ChoongKu Public Health Center in Seoul from May to August, 1989 and from March, 1990 to December, 1991. The results obtained were as follows.: 1. T. vaginalis was grown from only one of the 221 samples on TPS-1 meida. 2. In 208 NGU patients, there were 10(4.8%) positive reactions on IgG antibody in IFAT. 3. In 208 NGU patient, there were 14(6.7%) positive reactions to IgG antibody in ELISA. 4. No statistical significant correlation was found between then sults of IFAT and ELISA in individual patients. In conclusion, 1. Male trichomoniasis in patients with NGU was detected at a, significantly low rate. Due to the small number of patients in the test, further epidemiologic stidies of trichomoniasis in male NGU patient are necessary. 2. Serologic studies (IFAT and ELISA) have detected sorre trichomoniasis in male patients with NGU. These tests seem to be helpful in the diagnosis of male t-ichomoniasis.
Developing Countries ; Diagnosis* ; Enzyme-Linked Immunosorbent Assay ; Epidemiologic Studies ; Female ; Gonorrhea ; Humans ; Immunoglobulin G ; Korea ; Male* ; Public Health ; Seoul ; Serologic Tests* ; Urethritis*

Nine cases of primary localized cutaneous amyloidosis were studied by immunoperoxidase technique (ABC method) employing anti-keratin antibodies. All specimens were examined using consecutive paraffin sections to confirm the correspondence between amyloid existing area and reactive sites. Anti-keratin antibody 34pE which recognize 68, 58, 56.5, 56kd keratin peptides reacted with amyloid deposits in both lichen amyloidosus and macular amyloidosis. However, anti-keratin antibodies 34pB4 and 35pH did not react with amyloids. In general, Dylon staining positive material, keratin reacted with 34pE and amyloid P showed similar distribution in serial sections, but did not show the same one. Several keratin bodies reacted with 34pE, which were not stained with Dylon staining or antiamyloid P were found in the dermis of one specimen. These results suggest that immunohistochemical staining with antikeratin antibody 34pE using formalin-fixed, paraffin-embedded sections appeared to be a useful method in studying the histogenesis of primary localized cutaneous arnyloidosis.
Amyloid* ; Amyloidosis* ; Antibodies* ; Catalytic Domain ; Dermis ; Immunoenzyme Techniques ; Lichens ; Paraffin ; Peptides ; Plaque, Amyloid*

No abstract available.
Adult* ; Dental Pulp Cavity* ; Humans ; Incisor*