PURPOSE: Metastatic carcinoma of the eye is a common sequela of widespread dissemination of malignancy. Metastasis to the iris is less frequent than that of the cilliary body and choroid. We report a case of iris metastasis in a patient with non-small cell lung cancer. METHODS: 57-Year-Old man was seen in the department of ophthalmology because of blurred vision in his right eye for seven days. The patient had a metastasis of non-small cell lung cancer in the brain. Trabeculectomy and iridectomy were performed due to secondary glaucoma. RESULTS: The case was diagnosed as iris metastasis of non-small cell lung cancer by the clinical and histopathologic findings.
Brain ; Carcinoma, Non-Small-Cell Lung* ; Choroid ; Glaucoma ; Humans ; Iridectomy ; Iris* ; Middle Aged ; Neoplasm Metastasis* ; Ophthalmology ; Trabeculectomy

PURPOSE: To evaluate the clinical results of thermoplastic, hydrophilic acrylic IOL CV232 (MemoryLens(R), CIVA Vision, USA) to those of hydrophobic acrylic IOL AR40e (Sensar(R), AMO, USA). METHODS: Twenty patients had in-the-bag implantation of a MemoryLens(R) IOL in 1 eye and a Sensar(R) in the opposite eye in a randomized fashion after uneventful phacoemulsification. We evaluated the best corrected visual acuity (BCVA) and posterior capsule opacification (PCO) at a mean 30.05 months after surgery. RESULTS: Two years postoperatively, a BCVA of 0.8 or better was found in 65% of the MemoryLens(R) group and in 60% of the Sensar(R) group. There was no statistically significant differences between the two groups (p>0.50). PCO developed in 55% in the MemoryLens(R) group and in 65% of the Sensar(R) group. Again, no statistically significant differences were found between the two groups (p>0.50). CONCLUSIONS: There were no significant differences between the two different intraocular lenses in BCVA or PCO postoperatively.
Capsule Opacification ; Cataract* ; Humans ; Lenses, Intraocular* ; Phacoemulsification ; Refractive Errors ; Visual Acuity

PURPOSE: We evaluated the structure, distribution and innervation of the extraocular pulley smooth muscle in the rat, a species with a less complex visuomotor repertoire than primates. METHODS: The adult Sprague-Dawley rat was perfused transcardially with physiological saline followed by 4% formalin. The rat orbit was dissected en bloc, then paraffin processed and serially sectioned for hematoxylin-eosin and Masson's trichrome stain. The distribution and innervation of the extraocular pulley smooth muscle was confirmed by immunohistochemistry with human smooth muscle (SM) alpha-actin, tyrosine hydroxylase (TH) and neuronal nitric oxide synthase (nNOS). RESULTS: We found the pulley structure consist of focal condensations of eleastin and collagenous connective tissue in relationship to the rectus muscle in the equatorial Tenon's fascia. Especially, the pulley smooth muscle connected to medial rectus muscle was immunostained to TH and NOS. CONCLUSIONS: The data supports the presence of the extraocular pulley smooth muscle in the rat orbit supposing to have dopaminergic and nitroxidergic innervation.
Actins ; Adult ; Animals ; Collagen ; Connective Tissue ; Fascia ; Formaldehyde ; Humans ; Immunohistochemistry ; Muscle, Smooth* ; Nitric Oxide Synthase Type I ; Orbit ; Paraffin ; Primates ; Rats* ; Rats, Sprague-Dawley ; Tyrosine 3-Monooxygenase