1.Traditional use of Paris polyphylla and its active components.
Xiu-Xiang YAN ; Qi-Dong PAN ; Hao-Yun SUN ; Lu GAO ; Rong YANG ; Li-Xin YANG
China Journal of Chinese Materia Medica 2021;46(24):6343-6352
This paper reviewed the traditional use of Paris polyphylla and its active components, aiming to provide reference for the development and utilization of this plant. It was found that P. polyphylla has been used as a medicinal plant by eight ethnic minorities. A total of 62 experiential effective recipes, including 29 simple recipes and 33 compound recipes, were analyzed for their indications, traditional processing methods, medicinal compatibilities, and administration doses. The top three in the eight ethnic minorities sorted by the quantity of folk recipes were the Yi nationality(18), Naxi nationality(13) and Bai nationality(12). P. polyphylla has been widely employed for the treatment of nine categories of diseases, especially the dermatologic diseases, trauma, and toxicosis currently. The collating of material basis for its traditional functions revealed 26 active components, among which 19 were steroidal saponins capable of resisting cancer, furuncles, carbuncles, abscesses, bacteria, inflammation and stopping bleeding. This study preliminarily proved the efficacy of P. polyphylla in treating cancer and respiratory system, digestive system, and genitourinary system diseases, which has provided clues for related basic research of P. polyphylla and development of new preparations.
Ethnic and Racial Minorities
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Liliaceae
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Melanthiaceae
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Plants, Medicinal
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Saponins
2.Gene Mutation Types and Ethnic Distribution Characteristic of Thalassemia in Guiyang.
Fang WANG ; Ru-Yi ZHANG ; Dong-Yang DENG ; Di XU ; Yan ZOU ; Yi-Yuan ZHOU
Journal of Experimental Hematology 2021;29(6):1887-1891
OBJECTIVE:
To investigate the genetic mutation types and ethnic distribution characteristics of thalassemia in Guiyang.
METHODS:
The population underwent physical examination, antenatal examination and pre-pregnancy examination in our hospital from January 2019 to November 2019 was selected, and the thalassemia gene was detected by RDB-PCR.
RESULTS:
Among the 4 572 samples, 346 were positive , and the total carrying rate was 7.57%. The carrying rate of α-thalassaemia gene was 5.42% (248 cases), while β-thalassemia was 1.99% (91 cases), and α+β-compound thalassemia was 0.15% (7 cases). α-thalassaemia genotype with the lack of right side -α
CONCLUSION
The gene types of thalassemia in Guiyang are complex and varied. The -α
China
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Ethnic and Racial Minorities
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Ethnicity
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Female
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Humans
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Mutation
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Pregnancy
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alpha-Thalassemia/genetics*