The authors have experienced a case of acute hyperpyrexia with convulsion during diethyl ether anesthesia, which is rare and its etiology not well known.
Anesthesia* ; Ether* ; Seizures

Numerous reports of anaphylactoid reaction to d-tubocurarine have appeared since 1936. Also it has been suggested that histamine released as a consequence of clinical doses of d-tubocur arine is not in sufficient quantity to evoke symptoms. We recently had experience with a case who had of severe circulatory collapse and urticarial reaction while being anesthetized with ether and d-tubocurarine. This report draws attention to the risk of administering histamine releasing drugs and references are reviewed.
Anaphylaxis* ; Ether ; Histamine ; Shock ; Tubocurarine*

During ether anesthesia in man, succinylcholine(lmg/kg of body weight) was administered intravenously after pretreatment with 0.2% lidocaine 50-60mg or Inderal(1. 0mg). The effects were as follows: 1) Heart rates were increased during ether anestheaia. 2) Lidocaine produced no effects on heart rates rncreased by ether, but heart rates were decreased following administration of succinylcholine. 3) Inderal decreased heart rates, increased by ether anesthesia. Heart rates were increased following administration of succinylcholine.
Anesthesia ; Ether ; Heart Rate ; Lidocaine* ; Propranolol* ; Succinylcholine*

The petroleum ether fraction of ethanol extract of Acorus tatarinowii were separated by column chromatography and recrystallization to afford seven compounds. On the spectroscopic analysis, they were identified as 1-hydroxy-7(11),9-guaiadien-8-one (1), calamenone(2), cis-asarone(3), chrysophanol (4), physcion (5), emodin (6), (+)-galbacin (7). Compound 1 is a new compound. Compounds 4-7 were isolated from this plant for the first time.
Acorus ; chemistry ; Ethanol ; Ether ; Plant Extracts ; analysis

The effectivenss of intravenous Ritalin (10 mg vs. 20 mg) and nasal instillation of diethyl ether (2 cc) for the treatment of hiccup in 38 patients during and immediately following anesthesia. Ritalin, regardless of the dosage employed, was more effective than ether. Nausea and retching were more prevalent among patients treated with Ritalin, however, than with ether.
Anesthesia* ; Ether ; Hiccup* ; Humans ; Methylphenidate ; Nausea

This experiment was attemptel to observe possible effects of ether, halothane and methoxyflurane on the blood sugar level of the rabbit, 5, 15, 30 and 60 minutes after start of anesthesia with ether halothane and methoxyflurane by a non-rebreathing system. Comparision was made between preanesthetic and postanesthetic levels of blood sugar and the following results were obtained. In the ether anesthesia group, the blood sugar level 15 minutes after anesthesia was increased and decreased gradualley a anesthesia was progressed. In the halothane group, the blood sugar level was increased 5 minutes after anesthesia, and then decreased more rapidly than in other groups. Blood sugar levels 60 minutes after anesthesia had returned to preanesthetic levels in all groups. As the above result shows, blood sugar levels were revealed to have a tendency to increase during induction of anesthesia, and then returned gradually to the preanesthetic level during maintenence of anesthesia.
Anesthesia ; Blood Glucose* ; Ether ; Halothane ; Methoxyflurane

A 42-year-old Korean female patient with vitiligo universalis had depigmentation therapy with 20 monobenzyl ether of hydroquinone(MBEH). Noticeable lightening was observed 1 month after depigmentation therapy, three months later, complete depigmentation was achieved. As depigmentation induced by MBEH is generally irreversible, MBEH must be reserved for induction of complete depigmentation in severe cases of vitiligo in which the patients themselves do not want repigmentation and who can aecept the consequences of permanent non-tanning skin.
Adult ; Ether* ; Female ; Humans ; Skin ; Vitiligo*

In an attempt to observe possible effects of ether, halothane and methoxyflurane anesthesia on the protein contents of tracheobronchial washings in rabbits, the animals were subjected to moderate afiestbesia with ether, halotbane and methoxyflurane by a non- rebreathing system for one hour. A comparison was made of the protein contents of tracheobronchial washings and the ,results are summarized as follows; 1) The average protein contents of tracheobronchial washings of normal rabbits was 85. 8 +/-27. 44 umg/ml. 2) Increased protein contents of tracheobronchial washings were observed after ether, halothane and methoxyflurane anesthesia compared with the normal. It is concluded that inhalation anesthesia stimulates secreting glands of the tracheobronchial lumen.
Anesthesia ; Anesthesia, Inhalation ; Anesthetics* ; Animals ; Ether ; Halothane ; Methoxyflurane ; Rabbits*

While for the last thirty years Dapsone (4,4, diaminodiphenyl sulfone; DDS) has been the chemotherapeutic treatment of choice in the management of leprosy, other non-sulfone compounds have been used when patients have shown either sulfone resistance or sulfone sensitivity. Unfortunately, however, there have gradually appeared a significant number of dapsone resistant and non-sulfone resistant patients (i. e., patients resistant to the conventional chemotherapeutic management of leprosy), thus necessitating the synthesis of additional antileprotic medication. At present, it appears that Lamprene (Clofazimine) is the most adequate preparation for the treatment of sulfone and/or other anti-leprotic drug resistant cases, as well as reactive states. The work of Browne and Hogerzeil in 1962, and subsequent studies by ether workers, have demonstrated lamprenes anti-leprotic and anti-inflamatory effects. The drug has also been need successfully in the management of the reactive patient. However, as its most untoward side effect, the drug causes an unsightly darkening of the skin in those areas where the concentration of M. leprae is greatest. Because the literature provides only sparse data on the effect of lamprene on the morphological (MI) and bacteriological (BI) indices of bacteriologically open patients, the authors undertook the following study: Eighteen dapsone resistant patients, two of whom were in lepra, reaction, received a daily dose of 100mg. of lamprene during a period. ranging from 4 to 22 months. Patients were kept under close clinical observation and bacteriological samples were taken at an average of three month intervals from eight different sites on the body, All subjects were in residence at the National Leprosy Hospital of Korea on Sorok island. The study yielded the following results: 1) Within 3 to 8 months after the administration of lamprene, the MI decreas d to the base line in all patients save one. 2) In the short term administered group (less than 10 months), 6 of 1R patients showed a BI increase in inverse proportion to an MI decrease during the initial stage of lamprene administration. However, the BI began to decrease between the 4th and 5th months of treatment. Of the remaining 7 patients, all showed a decrease in both BI and MI. 8) In the long term administered group (more than 10 months), the BI, an indicat- or in the evaluation of long term administration, gradually decreased in 4 of 5 patients. In the remaining patients the BI increased. The authors regard the inverse relationship between the BI and MI as the result of the increment of bacilli secondary to the destruction of M. leprae by lamprene. That groups showed a decrease in both BI and Ml is interpreted as lamprenes biochemical intervention so as to render M. leprae more susceptible to phagocytosis. While. no ready explanation can account for the single case in which the BI increased and the MI also increased, the pos. ibility that there might be a strain of M. leprae resistant to lamprene must be ruled out. thus, given the above results, the authors conclude that lamprene is a valuable antileprotic drug not only for DDF>resistant patients but also for patients in lepra reaction. Moreover, this drug seems to find its best setting in the leprosarium where the untoward side effect of darkened skin does not in any way diminish the patients social relationships.
Clofazimine* ; Dapsone* ; Ether ; Humans ; Korea ; Leprosy ; Leprosy, Lepromatous* ; Phagocytosis ; Skin

PURPOSE: The purpose of this study was to determine whether in vitro plain radiography and ultrasonography(US) could predict the outcome of gallstone dissolution with methyl tert-butyl ether(MTBE). METHODS AND MATERIALS: The plain radiography and ultrasonography of 75 gallstones removed at surgery from 75 patients were obtained. The plaih radiographic findings were grouped by their calcification pattern as group l:lucent, group 2:central, group 3:diffuse and group 4: laminated. The ultrasonographic findings were grouped by their echo pattern as group 1 :arc shaped, clearly defined surface echo followed by distinct acoustic shadow, group 2:strong surface echo with gradually attenuating, meniscus shaped inner echo, group 3:strong surface echo with fill-in pattern of internal echo, group 4:strong surface echo with irregular inner echo and group 5:entirely discerning circumsference, homogeneous internal echotexture. After imaging, the gallstones underwent MTBE dissolution for 6 hours. The residual weight of each stone was measured every 2 hours. The correlation between imaging findings and dissolution rate was retrospectively analysed. RESULTS: The radiolucent and central calcification stones were dissolved rapidly as compared with the diffuse and laminated calcification stones(p<.05). There was no statistically significant difference among the groups based on ultrasonographic findings alone. However, after exclusion of the certain calcification groups that were resistent to dissolution-diffuse or laminated calcification stones-all US groups except one that shows wholly circumscribed margin and homogeneous fill-in pattern of internal echo dissolved well to average 20% or less of the original weight(p<.05). CONCLUSION: MTBE dissolution can be tried in stones that meet both ultrasonographic (not a stone with homogeneous fill-in pattern of internal echo) and plain radiographic (radiolucent or cental calcification stone) criteria.
Acoustics ; Ether* ; Gallstones* ; Humans ; Radiography* ; Retrospective Studies ; Ultrasonography*