Objective: To investigate the retinal nerve fiber layer (RNFL) thickness in essential tremor (ET). Methods: Twenty-seven eyes of 27 patients with essential tremor were included in this study. Twentyseven eyes of 27 healthy volunteers served as controls. All eyes were examined with spectral domain optical coherence tomography (OCT) (Retinascan Advanced RS-3000; NIDEK, Gamagori, Japan) using image filling software program (NAVIS-EX, NIDEK, Tokyo, Japan). Results: No statistically significant difference was detected between ET patients and control group for overall (RNFL) and foveal retinal thickness parameters. [RNFL thickness (Average thickness p=0.86, superior average p=0.22, inferior average p=0.24, nasal average p=0.06, temporal average p=0.88), foveal retinal thickness p=0.63] There was no relationship between OCT parameters and age, gender and duration of ET (all p>0.05). Conclusion: We did not find altered RNFL and foveal thickness values in patients with ET compared to controls. Retinal thickness changes do not seem to be a potentially useful biomarker in ET patients.
Essential Tremor

No abstract available.
Dystonia* ; Essential Tremor* ; Tremor*

Essential Tremor ; Humans ; Pedigree

No abstract available.
DNA, Mitochondrial* ; Essential Tremor* ; Humans

Primary writing tremor is considered to be a task-specific tremor occurring when handwriting. We describe the clinical and electrophysiological features of 5 patients. Two of the patients had a family history of the tremor. Alcohol was effective in reducing the tremor in 3 of the patients. Two patients showed a co-contraction and three alternate contractions between agonist and antagonist muscles. The frequency of the tremors was 5 to 6 Hz. Primidone and propranolol were effective in reducing tremor. Considering the clinical and electrophysiological features, it is suggested that primary writing tremor might be a variant of essential tremor. (J Korean Neurol Assoc 19(1):52~55, 2001
Essential Tremor ; Handwriting ; Humans ; Muscles ; Primidone ; Propranolol ; Tremor* ; Writing*

No abstract available.
DNA, Mitochondrial* ; Essential Tremor* ; Humans ; Parkinson Disease*

Adult ; Essential Tremor ; diagnosis ; Female ; Humans ; Male ; Pedigree

Adult ; Essential Tremor ; genetics ; Female ; Humans ; Male ; Middle Aged ; Pedigree

Tremor is defined as involuntary, rhythmic, and sinusoidal movement. The rate, location, amplitude, and constancy vary depending on the specific type of tremor and its severity. Etiologies and treatment of tremors differ according to the type of tremor. It is helpful to determine whether the tremor is present at rest, with posture-holding, with action or with intention maneuvers. Rest tremor is most typically present in patients with Parkinson's disease. Physiologic tremors and essential tremors are common forms of postural tremor. Intention tremor is typically present in cerebellar lesions. Associated neurological symptoms and signs are also helpful for differential diagnosis. Not all patients with hand tremor have Parkinson's disease. Rest tremor, bradykinesia, rigidity, and loss of postural reflex are cardinal signs of Parkinson's disease. Careful observation of the patient is the key point of diagnosis in patients with tremor.
Diagnosis ; Diagnosis, Differential ; Essential Tremor ; Hand* ; Humans ; Hypokinesia ; Intention ; Parkinson Disease* ; Reflex ; Tremor*

Hand tremor is one of the most frequent movement disorders and embarrassing symptoms of a wide spectrum of diseases. Hand tremor can be classified by form in which the hand tremor occurs, the main distinction being whether the hand tremor occurs at rest or is produced by voluntary muscle contractions. Essential tremor is the most common pathologic tremor in humans. The clinical features of essential tremor are heterogeneous across patients. Parkinson's disease is a common disease in the elderly with increasing prevalence over the last decade. Rest tremor is one of the cardinal motor features of Parkinson's disease. Drug-induced hand tremor is also common and should be diagnosed accurately. Hand tremor in Wilson's disease is very important to identify because the disease can be treatable. Here, the diagnosis and treatment of hand tremor were reviewed to provide a practical guide for managing patients with hand tremor.
Aged ; Contracts ; Essential Tremor ; Hand ; Hepatolenticular Degeneration ; Humans ; Movement Disorders ; Muscle, Skeletal ; Parkinson Disease ; Prevalence ; Tremor