2.Biomechanical Study of New Biodegradable Esophageal Stent.
Wentao YAN ; Hongyi YU ; Biao DING ; Zhongwei ZHENG ; Hang YAN ; Shengli LIN ; Pinghong ZHOU
Chinese Journal of Medical Instrumentation 2022;46(2):126-131
The radial force of the degradable esophageal stent before and after degradation is one of the important indicators for effective treatment of esophageal stricture. Based on a combination of in vitro experiments and finite element analysis, this paper studies and verifies the biomechanical properties of a new type of degradable esophageal stent under different esophageal stricture conditions. Under radial extrusion conditions, the maximum stress at the port of the stent is 65.25 MPa, and the maximum strain is 1.98%; The peak values of stress and strain under local extrusion and plane extrusion conditions both appear in the extrusion area and the compression expansion area at both ends, which are respectively 48.68 MPa, 46.40 MPa, 0.49%, 1.13%. The maximum radial force of the undegraded stent was 11.22 N, and 97% and 51% of the maximum radial force were maintained after 3 months and 6 months of degradation, respectively. The research results verify the safety and effectiveness of the radial force of the new degradable esophageal stent, and provide a theoretical basis for the clinical treatment of esophageal stricture.
Esophageal Stenosis/surgery*
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Finite Element Analysis
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Humans
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Mechanical Phenomena
;
Stents
3.Treatment of serious tracheal and esophagus narrow with nickel-titanium stand.
Zhao-Xin MA ; Ming LI ; Yong-Jiu HUANG ; Xingqiang GAO
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2005;40(2):151-152
Adult
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Aged
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Esophageal Stenosis
;
surgery
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Female
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Humans
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Male
;
Middle Aged
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Nickel
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Stents
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Titanium
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Tracheal Stenosis
;
surgery
4.Modified (Wu's) esophagectomy for a huge thoracic esophageal squamous cell carcinoma 18.3 cm in length.
Xu WU ; Zhen-Zhong ZHANG ; Nan-Bo LIU ; Jun-Hua ZHANG
Journal of Southern Medical University 2016;36(7):1018-1020
An esophageal squamous cell carcinoma measuring 18.3 cm in length and 5 cm in diameter was found in the mediastinum of a 53-year man. The patient underwent a modified 3-stage esophagectomy and an esophagogastrostomy at the cervical level (Wu's method). The operation was performed smoothly and the patient recovered uneventfully after the operation. The patient was followed up for 6 months after discharge and reported no difficulties in eating with improved quality of life. This case represents the world's longest esophageal cancer that had been surgically removed. Local advanced esophageal cancer should be removed immediately to prevent potential occurrence of esophageal obstruction, tracheoesophageal fistula or aorto-esophageal fistula.
Carcinoma, Squamous Cell
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surgery
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Esophageal Fistula
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Esophageal Neoplasms
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surgery
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Esophageal Stenosis
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Esophagectomy
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Female
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Humans
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Male
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Middle Aged
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Quality of Life
5.Application of gastric tube esophagoplasty to complicated diseases of esophagus in children.
Jiahang ZENG ; Wei LIU ; Jianhua LIANG ; Fenghua WANG ; Hui WANG ; Jue TANG
Chinese Journal of Gastrointestinal Surgery 2018;21(9):1025-1031
OBJECTIVETo summarize the experience of applying gastric tube esophagoplasty for complicated diseases of esophagus in children and the short-middle-term efficacy.
METHODSA retrospective and observational case series study was performed.
INCLUSION CRITERIA(1) burn length of esophagus > 2 cm, multisegmental or extensive esophageal scar stenosis, and about 6 months after burn; (2) longitudinal diameter of esophageal tumor > 2 cm, or esophagus considered as impossible to reserve;(3) Severe esophageal fistula with diameter > 2 cm, or relapse again after ≥3 times of repair; (4) Tracheal cartilaginous esophageal heterotopia with a length of >2 cm or no end to end anastomosis after removal of the esophageal lesion.
EXCLUSION CRITERIApatients with severe cardiopulmonary insufficiency, or poor prognosis of gastric primary disease; the gastric volume did not allow long enough gastric tube; the parents did not accept the surgery. According to above criteria, 36 children with complicated diseases of esophagus who underwent gastric tube esophagoplasty at Department of Thoracic Surgery, Guangzhou Women and Children's Medical Center from March 2010 to June 2017 were enrolled into this study. Among 36 children, 27 were with corrosive strictures of esophagus, 5 with esophageal tumor, 3 with severe esophageal fistula, and 1 with tracheal cartilaginous esophageal heterotopia. Above-mentioned 27 cases with corrosive strictures of esophagus underwent gastric tube esophagoplasty via retrosternal route with preservation of the original esophagus. The other 9 cases underwent resection for esophageal lesion and gastric tube esophagoplasty via prevertebral route. The construction of gastric tube was as follows: the stomach was cut along the lesser curvature from pylorus to cardia and fundus of stomach with stapler, making the diameter of the gastric tube equal to pylorus. Operative time, intra-operative bleeding, time of mechanical ventilation, anastomotic leakage, anastomotic stricture were observed. The postoperative short-middle-term growth presentation of children was evaluated according to CDC 2000 children growth evaluation table(2 to 20 years).
RESULTSAll the 36 children survived their operations successfully. Nine cases underwent esophagectomy for lesion esophagus and the other 27 cases received preservation of original esophagus. Average time of postoperative mechanical ventilation was 8 (4-20) hours. Three cases developed anastomotic leakage and were healed after one week. Eight cases developed anastomotic stricture and resumed normal diet after balloon expansion. The patients were followed up from 6 months to 7 years. Five cases were found to have esophageal cyst 4-8 months after the operation, and received resection. One children with infantile esophageal fibrosarcoma recurred 3 weeks after the operation and died 2 weeks later because the family abandoned the treatment. The quality of life of 35 cases was improved significantly. Short-middle-term body height and weight in 85.7%(30/35) children met basically the criteria of CDC 2000 children growth evaluation table.
CONCLUSIONGastric tube esophagoplasty can effectively treat the children with complicated esophagus diseases with good short-middle-term efficacy, and is a recommended esophageal replacement surgery.
Burns ; surgery ; Child ; Esophageal Diseases ; surgery ; Esophageal Stenosis ; surgery ; Esophagoplasty ; Female ; Humans ; Quality of Life ; Retrospective Studies ; Stomach
6.Stent implantation in the treatment of pharynx anastomotic stenosis after cervical esophageal resection: a case report.
Chuanshan ZANG ; Jian SUN ; Yan SUN
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2016;30(5):417-417
We report the treatment of one patient with pharynx anastomotic stenosis after cervical esophagealresection by stent implantation. The patient suffered from serious pharynx anastomotic stenosis after gastric-pha-ryngeal anastomosis. After balloon-dilatation,a domestic self-expanding Z-stents was implanted in the stricture ofthe esophagus under the X-rays. After stent implantation, the patient has been leading a normal life for threeyears. Balloon dilatation and stent implantation is an effective and safe method in the treatment of patients withpharynx anastomotic stenosis.
Anastomosis, Surgical
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Catheterization
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Constriction, Pathologic
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Esophageal Stenosis
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surgery
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Esophagus
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surgery
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Humans
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Pharyngeal Diseases
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Pharynx
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surgery
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Stents
7.Synthetic evaluation of precancerous lesions and early esophageal cancers after endoscopic submucosal dissection.
Ansheng LING ; Fanglai ZHU ; Ping WU ; Chongwen FANG ; Fuliu CAO
Journal of Central South University(Medical Sciences) 2016;41(1):71-77
OBJECTIVE:
To evaluate the safety and prognosis for patients with early esophageal cancer and precancerous lesions after endoscopic submucosal dissection (ESD).
METHODS:
A total of 89 patients were admitted to the Department of internal medicine in the First People's Hospital of Anqing from August 2008 to August 2011. All patients were treated with ESD at the early stage of esophageal cancer and precancerous lesions. The patients' laboratory data and relevant medical history were collected. The postoperative complications and long-term effects of ESD were analyzed.
RESULTS:
Eighty-nine patients were followed up with 100% response rate. Among 89 cases, 16 were early esophageal cancer, 38 were high-grade esophageal neoplasia and 35 were low-grade esophageal neoplasia. The one-time whole piece resection rate, complete resection rate and curative resection rate was 93.3% (84/89), 92.1% (82/89) and 92.1% (82/89), respectively. Two cases suffered intraoperative perforation with a rate of 2.2% and these 2 patients performed the intraoperative endoscopic repair; one case suffered the postoperative delayed bleeding with a rate of 1.1% and the patient underwent the conservative treatment; three cases suffered the esophageal stenosis with a rate of 3.4%. All patients were followed-up for 10-58 (36.3±21.2) months. In this period, one case recurred after ESD for 3 years with a rate of 1.1%; two cases were dead. The three-year survival rate was 97.8%.
CONCLUSION
The early esophageal cancer and precancerous lesions can be treated with ESD. The method is safe and the prognosis is good.
Dissection
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Endoscopy
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adverse effects
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Esophageal Neoplasms
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surgery
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Esophageal Perforation
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Esophageal Stenosis
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Humans
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Postoperative Complications
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Postoperative Hemorrhage
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Prognosis
8.Applicability of skin flaps and myocutaneous flaps for esophageal surgery.
Ruwen WANG ; Jinghai ZHOU ; Bo DENG
Chinese Journal of Gastrointestinal Surgery 2014;17(9):861-864
Stomach and colon are always used to reconstruct esophagus after esophagectomy. However, alternative procedures to reconstruct or repair esophagus are required if the patients suffered from gastric or colonic diseases, underwent gastric colonic operations or had severe local esophageal stricture. More than ten kinds of skin flaps and myocutaneous flaps, which are classified into free or pedicled ones, are used to reconstruct or repair esophagus. Microvascular anastomosis is required while using free flaps. Necrosis of the free flaps is prone to developing once the vascular occlusion occurs. The pectoralis major myocutaneous and latissimus dorsi pedicled flaps have sufficient blood supplies. However, both are bulky and difficult to reconstruct a circumferential esophagus through contouring a tube. Platysma myocutaneous flaps have a large surface area and are supplied from multiple vessels. Single lateral and bilateral platysma myocutaenous flap can be applied to repair the cervical esophageal defect and circumferential cervical esophagus, respectively. The use of platysma myocutaneous to repair and reconstruct cervical esophagus is a procedure easy to perform and confer excellent outcomes. There is no development of ulcer and hair growth after long-term follow-up and resistance to radiotherapy.
Esophageal Stenosis
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surgery
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Esophagus
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surgery
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Humans
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Myocutaneous Flap
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surgery
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Neck
;
surgery
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Reconstructive Surgical Procedures
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methods
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Surgical Flaps
;
surgery
9.Investigation of the technique of esophageal stent re-implantation.
Qunqing CHEN ; Jian TONG ; Fuwei ZHANG ; Guangxing LIANG ; Yuanzhou WU ; Shaobin LI ; Yusheng YAN
Journal of Southern Medical University 2012;32(10):1525-1527
OBJECTIVETo analyze the causes of failure of esophageal stent implantation and explore technical improvement of re-implantation of esophageal stent (RIES).
METHODSAccording to the conditions of the failed stent implantation, 32 patients who required RIES underwent placement of more appropriate esophageal stents with an improved implantation technique. The patients were followed up for 6 months after the operation to evaluate the effects of RIES.
RESULTSThe success rate of the operation was 96.9% in these cases, and the esophageal conditions including stricture and fistula were effectively relieved. During the 6-month follow-up, stent migration occurred in 4 cases (12.5%), and esophageal fistula in the upper edge of the re-implanted stent occurred in 2 cases. No stent loss, bleeding, or stricture was found in these cases.
CONCLUSIONThe improved technique is effective for stent re-implantation after failed esophageal stent implantation with reduced complications associated with esophageal stenting.
Esophageal Fistula ; surgery ; Esophageal Neoplasms ; surgery ; Esophageal Stenosis ; surgery ; Female ; Humans ; Male ; Middle Aged ; Prosthesis Failure ; Prosthesis Implantation ; Reoperation ; Stents ; Treatment Outcome
10.The impact of nasogastric tube placement on the postoperative nausea and vomiting of patients who are undergoing cardiac surgery.
Kyong Sil IM ; Jong Bun KIM ; Jae Myeong LEE ; Hyun Ju JUNG ; Seung Hwa OH
Anesthesia and Pain Medicine 2009;4(4):314-317
BACKGROUND: The incidence of postoperative nausea and vomiting after cardiac surgery is 30-40%.The role of a nasogastric tube for reducing the PONV is still controversial. METHODS: 92 patients who were undergoing cardiac surgery with cardiopulmonary bypass were randomized to a receive nasogastric tube after induction of anesthesia (Group 2) or they were placed in the control group (no nasogastric tube) (Group 1).The patients with a history of gastric/esophageal surgery, esophageal varix, esophageal stricture and/or a history of antiemetic treatment were excluded.Routine fast-track cardiac anesthesia and postoperative care were employed for all the patients.The incidence of PONV was recorded hourly for the first four hours after extubation and then every 4 h afterwards for 24 h.The usage of antiemetics and pain medication was also recorded.The data was analyzed with t-tests and chi-square tests for the continuous variables and the categorical data, respectively.P values < 0.05 were considered statistically significant. RESULTS: The groups were similar with respect to the demographic data, the surgical characteristics and the opioid usage.There was no significant difference in the incidence of PONV and the antiemetic usage between the two groups. CONCLUSIONS: This study showed that placement of a nasogastric tube did not have an impact on the incidence of PONV or the requirements for antiemetics after cardiac surgery.The results of this study do not support the use of a nasogastric tube to reduce PONV after cardiac surgery.
Anesthesia
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Antiemetics
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Cardiopulmonary Bypass
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Esophageal and Gastric Varices
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Esophageal Stenosis
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Humans
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Incidence
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Postoperative Care
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Postoperative Nausea and Vomiting
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Thoracic Surgery