2.New developments for endoscopic management of Barrett's esophagus with high grade dysplasia.
Journal of Zhejiang University. Medical sciences 2010;39(5):534-541
Barrett's esophagus is now clearly recognized as a preneoplasic condition. Progression of metaplasia through dysplasia to adenocarcinoma is a widely accepted theory for esophageal carcinogenesis. That high grade dysplasia is frequently found in association with esophageal adenocarcinoma. Long-term endoscopic surveillance of high grade dysplasia in Barrett's esophagus facilitates detection and treatment of esophageal cancers in the early stage.
Barrett Esophagus
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diagnosis
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pathology
;
therapy
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Esophageal Neoplasms
;
diagnosis
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Esophagoscopy
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Humans
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Hyperplasia
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pathology
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Precancerous Conditions
;
diagnosis
3.A Case of Primary Intestinal T-Cell Lymphoma Involving Entire Gastrointestinal Tract: Esophagus to Rectum .
Myung Ju AHN ; Yong Wook PARK ; Dongsoo HAN ; Jung Hae CHOI ; Sung June SHIN ; Byung Chul YOON ; Ho Soon CHOI ; Young Yeul LEE ; Tae June JUNG ; Il Young CHOI ; Moon Hyang PARK ; In Soon KIM
The Korean Journal of Internal Medicine 2000;15(3):245-249
Primary intestinal T-cell lymphoma is a rare disease entity, which is approximately 10% to 25% of intestinal lymphomas, and most of the lymphomas occur in the small intestine. We report here a case of a 56-year-old woman who has been suffering from chronic diarrhea and weight loss for 6 months. Abdominal CT scan and small bowel series showed diffuse wall thickening of the small bowel. Gastroscopic examination showed diffuse erythematous lesions on the esophagus and small gastric ulcerations on the antrum of the stomach, and colonoscopic examination also showed multiple punched-out ulcerations and erosions on the entire colon, including the sigmoid colon to the terminal ileum. Diffuse infiltration of CD 3 positive lymphoma cells was found on biopsy. The patient was diagnosed as primary intestinal T-cell lymphoma with diffuse involvement of the entire gastrointestinal tracts from the esophagus to the rectum. Although the patient received systemic combination chemotherapy and achieved partial response initially, the lymphoma relapsed repeatedly.
Case Report
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Esophageal Neoplasms/therapy*
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Esophageal Neoplasms/pathology
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Esophageal Neoplasms/diagnosis
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Female
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Gastrointestinal Neoplasms/therapy*
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Gastrointestinal Neoplasms/pathology
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Gastrointestinal Neoplasms/diagnosis
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Human
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Lymphoma, T-Cell/therapy*
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Lymphoma, T-Cell/pathology
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Lymphoma, T-Cell/diagnosis
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Middle Age
4.A Case of Esophageal Squamous Papillomatosis.
Sang Hyun PARK ; Byoung Wook BANG ; Hyung Gil KIM ; Yong Woon SHIN ; Lucia KIM
The Korean Journal of Internal Medicine 2012;27(2):243-243
No abstract available.
Aged
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Biopsy
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Esophageal Neoplasms/*diagnosis/pathology
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Esophagoscopy
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Esophagus/*pathology
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Humans
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Male
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Mucous Membrane/pathology
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Papilloma/*diagnosis/pathology
5.Narrow-band imaging in the diagnosis of early esophageal cancer and precancerous lesions.
Liu-Ye HUANG ; Jun CUI ; Cheng-Rong WU ; Yun-Xiang LIU ; Ning XU
Chinese Medical Journal 2009;122(7):776-780
BACKGROUNDIn the recent years, the incidence of esophageal cancer in China has increased. The key point for raising the survival rate is the diagnosis and treatment at an early stage. Narrow-band imaging (NBI) can enhance the contrast of the mucous membrane of the esophagus without staining. This study aimed to explore the value of NBI in the diagnosis of early esophageal cancer and precancerous lesions.
METHODSThe esophagus was examined with ordinary endoscopy and NBI endoscopy. Pit patterns and blood capillary forms were examined with routine magnifying endoscopy and NBI endoscopy. Finally, a 1.2% Lugoul's iodine solution was used to stain the esophageal mucosal surface and a biopsy was taken at all the sites where NBI or iodine staining was positive. NBI and iodine staining scales were compared with pathologic diagnosis, which was considered as the gold standard.
RESULTSA total of 90 cases (138 lesions in total) were diagnosed as early esophageal cancer or precancerous lesions; 104 lesions (75.4%) were detected with ordinary endoscopy, 120 lesions (87.0%) were detected with NBI endoscopy, and 138 lesions (100%) were detected with iodine staining. The lesion detection rate of NBI was significantly lower than that of iodine staining (chi(2) = 17.176, P < 0.01). However, there was no significant difference between NBI and iodine staining for the diagnosis of high grade intraepithelial neoplasia (chi(2) = 1.362, P > 0.05), while the detection rate of NBI was significantly lower than that of iodine staining for the diagnosis of low grade intraepithelial neoplasia (chi(2) = 13.388, P < 0.01). The pit pattern and blood capillary form of early esophageal cancer and precancerous lesions could be demonstrated clearer with NBI than with ordinary endoscopy.
CONCLUSIONSNBI can enhance the contrast of the mucous membrane of the esophagus without staining. The combination of NBI and iodine staining can raise the diagnostic rate of early esophageal cancer and precancerous lesions.
Adult ; Aged ; Esophageal Neoplasms ; diagnosis ; pathology ; Esophagoscopy ; methods ; Esophagus ; pathology ; Female ; Humans ; Male ; Middle Aged ; Precancerous Conditions ; diagnosis ; pathology
6.Pseudoepitheliomatous Hyperplasia Mimicking Esophageal Squamous Cell Carcinoma in a Patient with Lye-induced Esophageal Stricture.
Jang Soo HAN ; Sang Woo LEE ; Kang Heum SUH ; Seung Young KIM ; Jong Jin HYUN ; Sung Woo JUNG ; Ja Seol KOO ; Hyung Joon YIM
The Korean Journal of Gastroenterology 2014;63(6):366-368
Pseudoepitheliomatous hyperplasia is a benign condition that may be caused by prolonged inflammation, chronic infection, and/or neoplastic conditions of the mucous membranes or skin. Due to its histological resemblance to well-differentiated squamous cell carcinoma, pseudoepitheliomatous hyperplasia may occasionally be misdiagnosed as squamous cell carcinoma. The importance of pseudoepitheliomatous hyperplasia is that it is a self-limited condition that must be distinguished from squamous cell carcinoma before invasive treatment. We report here on a rare case of esophageal pseudoepitheliomatous hyperplasia in a 67-year-old Korean woman with a lye-induced esophageal stricture. Although esophageal pseudoepitheliomatous hyperplasia is infrequently encountered, pseudoepitheliomatous hyperplasia should be considered in the differential diagnosis of esophageal lesions.
Aged
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Carcinoma, Squamous Cell/diagnosis
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Diagnosis, Differential
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Esophageal Neoplasms/diagnosis
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Esophageal Stenosis/chemically induced/*diagnosis
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Esophagoscopy
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Female
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Humans
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Hyperplasia/*diagnosis/pathology
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Iodides/chemistry
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Lye/*toxicity
7.Pseudoepitheliomatous Hyperplasia Mimicking Esophageal Squamous Cell Carcinoma in a Patient with Lye-induced Esophageal Stricture.
Jang Soo HAN ; Sang Woo LEE ; Kang Heum SUH ; Seung Young KIM ; Jong Jin HYUN ; Sung Woo JUNG ; Ja Seol KOO ; Hyung Joon YIM
The Korean Journal of Gastroenterology 2014;63(6):366-368
Pseudoepitheliomatous hyperplasia is a benign condition that may be caused by prolonged inflammation, chronic infection, and/or neoplastic conditions of the mucous membranes or skin. Due to its histological resemblance to well-differentiated squamous cell carcinoma, pseudoepitheliomatous hyperplasia may occasionally be misdiagnosed as squamous cell carcinoma. The importance of pseudoepitheliomatous hyperplasia is that it is a self-limited condition that must be distinguished from squamous cell carcinoma before invasive treatment. We report here on a rare case of esophageal pseudoepitheliomatous hyperplasia in a 67-year-old Korean woman with a lye-induced esophageal stricture. Although esophageal pseudoepitheliomatous hyperplasia is infrequently encountered, pseudoepitheliomatous hyperplasia should be considered in the differential diagnosis of esophageal lesions.
Aged
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Carcinoma, Squamous Cell/diagnosis
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Diagnosis, Differential
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Esophageal Neoplasms/diagnosis
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Esophageal Stenosis/chemically induced/*diagnosis
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Esophagoscopy
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Female
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Humans
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Hyperplasia/*diagnosis/pathology
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Iodides/chemistry
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Lye/*toxicity
8.Imaging Findings of Giant Liposarcoma of the Esophagus.
Jae Joon CHUNG ; Myeong Jin KIM ; Joo Hee KIM ; Jong Tae LEE ; Hyung Sik YOO ; Ki Whang KIM
Yonsei Medical Journal 2003;44(4):715-718
A giant esophageal liposarcoma showing rapid growth over 7 months is presented in 56-year-old man. It originated from the pharyngo-esophageal junction with a short stalk, and extended downward to the distal esophagus. A barium swallow study showed a large, sausage-like intraluminal mass in the dilated esophagus. CT and MR imaging showed a heterogeneous mass with a fatty component in the esophagus. A total laryngopharyngo-esophagectomy was performed and the histological diagnosis was of a well-differentiated liposarcoma.
Esophageal Neoplasms/*diagnosis/pathology
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Esophagus/radiography
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Human
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Liposarcoma/*diagnosis/pathology
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Magnetic Resonance Imaging
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Male
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Middle Aged
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Tomography, X-Ray Computed
9.Well-differentiated liposarcoma of esophagus.
Bin YANG ; Pei-zhi SHI ; Xiao LI ; Ru-jun XU
Chinese Medical Journal 2006;119(5):438-440
10.The Role of Endoscopic Ultrasonography in Staging of Esophageal Cancer : Preliminary Report.
Young Jun SHIN ; Jae Back CHUNG ; Si Young SONG ; Jun Oh PARK ; Jin Kyung KANG ; In Suh PARK ; Chung Bae KIM ; Ji Young HAN ; Chan Il PARK
Korean Journal of Gastrointestinal Endoscopy 1993;13(3):539-543
The prognosis of esophageal cancer is poor and strategies for treatment depend on the tumor stage at the time of diagnosis. Surgery is the main therapeutic modality in esophageal cancer and known as the only treatment for cure. Preoperatively it is most important to assess whether the primary tumor is completely resectable or not. Previous staging modality such as CT can not clearly define the depth of invasion and lymph node metastasis of esophageal cancer which is the most important factor in assessing the possibility of curative resection. Endoscopic ultrasonography is now considered as an useful method in evaluating staging and resectability of esophageal cancer. We compared the findings of endoscopic ultrasonography with pathology result to evaluate the accuracy of this new technique in staging of esophageal cancer in 4 esophageal cancer patients who received surgery among the 23 patients assessed by endoscopic ultrasonography due to esophageal cancer, The depth of invasion, lymph node metastasis, and staging was correct in 3 among 4 patients. We consider endoscopic ultrasonography is an useful technique in staging of esophageal cancer.
Diagnosis
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Endosonography*
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Esophageal Neoplasms*
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Humans
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Lymph Nodes
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Neoplasm Metastasis
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Pathology
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Prognosis