We present a case of carcinoma erysipelatoides which or iginated from an internal organ. The patient was a 50 year-old female who had peritoneal carcinomatosis, She presented an erythematous lesion resembling erysipelas on her right breast. Histopathologic findings were consistent with metastatic adenocarcinoma but clinically it was not associated with carcinoma of the breast.
Adenocarcinoma ; Breast ; Carcinoma ; Erysipelas ; Female ; Humans ; Middle Aged

Porcine parvovirus, Erysipelothrix (E.) rhusiopathiae, and Leptospira (L.) interrogans are considered major etiologic agents of reproductive failure in pigs, causing economic loss in the swine industry. In this study, the safety and immunogenicity of a new octavalent inactivated vaccine were evaluated. The vaccine contained inactivated porcine parvovirus, E. rhusiopathiae, and six L. interrogans serovars (Bratislava, Canicola, Grippotyphosa, Hardjo, Icterohaemorrhagiae, and Pomona). Safety test results showed no notable side effects or clinical signs after vaccination in mice, guinea pigs, and sows. In addition, we assessed immunogenicity of the vaccine in 25 sows under field conditions. The vaccinated group (n = 20) had a significantly higher antibody level than the non-vaccinated group (n = 5). Moreover, the stillbirth rate decreased in piglets born from vaccinated sows, resulting in an increased fertility rate. The results of this study demonstrate that the new octavalent inactivated vaccine can be applied safely and effectively to improve reproductive performance in sows.
Animals ; Birth Rate ; Erysipelas* ; Erysipelothrix ; Guinea Pigs ; Leptospira* ; Leptospirosis ; Mice ; Parvovirus, Porcine* ; Serogroup ; Stillbirth ; Swine ; Vaccination

Cutaneous angiosarcoma is a rare, aggressive vascular malignancy with a grave prognosis. It usually arises in the scalp or face as a locally-advanced patch, plaque or tumor at presentation and most often affects males and the elderly. Histopathologically, well-differentiated angiosarcomas are composed of well- or ill-formed vascular channels, often lined by flattened atypical endothelial cells and are distinguished from benign counterparts by their so-called "collagen dissection pattern" and anastomosing architecture. Varied differentiation may be observed even in the same tumor. Epithelioid angiosarcoma is a rare variant of poorly-differentiated angiosarcoma. The patients were seven cases of angiosarcomas including an epithelioid variant. They were six males and one female with an age range between 65~84 years (avg. 74 years). Lesions resembled seborrheic dermatitis, erysipelas or "spreading bruise" that varied from blue to red in color and from papule to mass in size. They revealed satellite lesions far from the main lesion in some cases. Skin biopsies were performed for all patients and histopathologic features were compatible with angiosarcoma and epithelioid angiosarcoma. We herein report seven angiosarcomas of diverse clinical features because their early detection and precise differential diagnosis should be mandatory for effective management.
Aged ; Biopsy ; Dermatitis, Seborrheic ; Diagnosis, Differential ; Endothelial Cells ; Erysipelas ; Female ; Hemangiosarcoma* ; Humans ; Male ; Prognosis ; Scalp* ; Skin

Necrotizing fasciitis is rare acute infection showing rapidly necrosis involve the subcutaneous tissue and fascia. If treatment is delayed, infection can spread to involve the subcutaneous tissue, skin, deep fascia, and even muscle in rapid sequence, resulting in widespread necrosis and moderate to severe systemic toxicity. Most commonly this disease presents in the extremities, trunk, and perineum; it is relatively rare in the head and neck regions. If not diagnosed and treated in its early stages, necrotizing fasciitis can be potentially fatal, with a motality rate approaching 40%. Historically, the clinical entity now referred to as necrotizing fasciitis was described in the literature under various name. : hospital gangrene, necrotizing erysipelas, streptococcal gangrene, suppurative fasciitis. Necrotizing fasciitis was first described by Wilson in 1952. We experienced 3 cases of necrotizing fasciitis and will report review of literature with diagnosis, treatment, complication and consideration.
Diagnosis ; Erysipelas ; Extremities ; Fascia ; Fasciitis ; Fasciitis, Necrotizing* ; Gangrene ; Head ; Neck ; Necrosis ; Perineum ; Skin ; Subcutaneous Tissue

A 51-year-old Korean woman presented with a non-tender, well-demarcated, reddish, edematous patch on the right anterior chest where a previous mastectomy and radiation therapy had been performed. She had been diagnosed as having infiltrating ductal carcinoma of the right breast about 1 year ago. Histopathological findings of the skin lesions were consistent with inflammatory metastatic carcinoma of the breast. Inflammatory carcinoma or carcinoma erysipeloides is a well-established entity most frequently associated with carcinoma of the breast. It is characterized by dermal lymphatic invasion by malignancy and clinically should be distinguished from erysipelas or cellulitis. We describe a case of inflammatory metastatic carcinoma derived from an infiltrating ductal carcinoma of the breast which can be clinically confused with radiation dermatitis.
Breast* ; Carcinoma, Ductal ; Cellulitis ; Dermatitis ; Erysipelas ; Erysipeloid ; Female ; Humans ; Mastectomy ; Middle Aged ; Skin ; Thorax

Sweet's syndrome (SS) or acute febrile neutrophilic dermatosis has been reported to occur in association with many conditions. We report two cases of SS at the site of a postmastectomy lymphedema. A localized variant of SS restricted to an area of postmastectomy lymphedema is an often unrecognized complication of breast cancer. Moreover, attempts to treat SS using various methods might prolong the duration of treatment. Therefore, SS should not be confused with other disorders such as erysipelas, cellulitis, herpes zoster, and contact dermatitis.
Breast Neoplasms ; Cellulitis ; Dermatitis, Contact ; Erysipelas ; Herpes Zoster ; Lymphedema* ; Sweet Syndrome*

In dermatologic practice, acute urticaria showing leukocytosis and fever suggesting syatemic bacterial infection is often observed. The clinician in dealing with such patients is tempted to use antibiotics in addition to corticosteroids and antihistamines before the patient can be sure that there is no bacterial infection. Authors observed the degree of the leukocytosis with its differential counts in 106 cases of acute urticaria to evaluate what percentages of acute urticaria patients are showing similar data with the changes seen in leukocyte counts of patients of erysipelas, and evaluated the effect of aqtibiotics-administered group with non-administered group of acute urticaria patients. The results were as follows: 1. In 106 acute urticaria patients, 42% showed higher total leukocyte count ( >12, 500/cu mm) than the mean total leukocytes of 20 erysipelas patients(12, 412/cu mm) and 29% showed greater neutrophilia(>70%) than the mean neutrophil differential count of the erysipelas (69.1%). In the cases showing both leukocytosis (>12,500/cu mm) and fever (>37. 5C) there was no difference in the course of treatment between the antibiotics-administered group and non-administered group. 3. The corticosteroid hormone reduced the total WBC count toward normal level generally within a week.
Adrenal Cortex Hormones ; Anti-Bacterial Agents ; Bacterial Infections ; Erysipelas ; Fever ; Histamine Antagonists ; Humans ; Leukocyte Count ; Leukocytes* ; Leukocytosis ; Neutrophils ; Urticaria*

Elephantiasis nostras, the result of recurrent skin infection or chronic lymphedema is characterized by marked skin fibrosis and massive enlargement of a body part. We present a case of elephantiasis nostras due to chronic recurrent erysipelas which affected the lower extremities in a 62-year-old man. The patient had had persisting non-pitting edema, and tender multiple verrucous brownish plaques and nodules on both lower legs for 1 year. On histological examination, there was hyperkeratosis and papilomatosis in the epidermis, fibroplasia, dilated thick walled venules and collagen fibers oriented vertical to the skin surface, and hyperplasia of eccrine ducts in the dermis.
Collagen ; Dermis ; Edema ; Elephantiasis* ; Epidermis ; Erysipelas ; Fibrosis ; Humans ; Hyperplasia ; Leg ; Lower Extremity ; Lymphedema ; Middle Aged ; Skin ; Venules

BACKGROUND: Cellulitis is an acute infection of the dermal and subcutaneous layers of the skin, which is commonly treated by a dermatologist but there are few reports about clinical data on cellulitis in Korean literature. OBJECTIVE: This study evaluated the clinical characteristics of inpatients diagnosed as cellulitis in the recent 5 years. METHODS: We reviewed the medical records of 77 patients who were diagnosed as cellulitis and hospitalized at the Kangbuk Samsung Hospital from March 2008 to February 2013. RESULTS: The study included data from 77 patients with cellulitis (mean age, 51.7 years; 44 men, 33 women). There was a positive correlation between age and hospitalized days (p<0.05). Cellulitis most frequently occurred in the foot (32.1%). The most common cutaneous symptoms were erythema, tenderness, and swelling (100%), and the most common systemic symptom was fever (23.4%). Tinea pedis was the most common cause of cellulitis (31.2%). Elevation of C-reactive protein (CRP) was observed in 30 patients (40%) and there were positive correlations not only between CRP and hospitalized days (p<0.05) but also between white blood cell (WBC) count and hospitalized days (p<0.05). First-generation cephalosporin was chosen as the primary antibiotic in 33 patients (40.3%) and the mean duration of antibiotic treatment was 12.4 days. There was no significant difference of hospitalized days between first-generation cephalosporin and other antibiotics (p>0.05). Systemic steroid was administered in 21 patients (27.3%), and was not significantly related to hospitalized days (p>0.05). CONCLUSION: The clinical course of cellulitis was inversely correlated to the elevation of patient's age, WBC count, and CRP.
Anti-Bacterial Agents ; C-Reactive Protein ; Cellulitis* ; Erysipelas ; Erythema ; Fever ; Foot ; Humans ; Inpatients* ; Leukocytes ; Male ; Medical Records ; Skin ; Tinea Pedis

BACKGROUND: Cutaneous angiosarcoma (CAS) is occasionally difficult to differentiate with other benign dermatoses, clinically, because of various clinical manifestations. OBJECTIVE: The aim of this study is to examine the clinical and histopathologic findings of CAS, and investigate specific clinicopathologic features to aid in the early diagnosis. METHODS: We reviewed photographs, medical records and biopsy specimen of 10 cases diagnosed as CAS for 5 years at our clinic. RESULTS: The male and female numbers were 7 and 3, and the mean onset age was 69.7 years old. The mean duration of disease was 5.7 months. The site of involvement was scalp or face in all patients. The most common clinical feature was erythematous or purpuric nodule, with surrounding erythematous or purpuric patch, without symptoms. Initial impressions based on clinical findings on the first visit of our clinic were CAS (n=6), squamous cell carcinoma (n=2), basal cell carcinoma (n=1), and erysipelas (n=1). Histopathologically, irregular vascular channels lined by atypical endothelial cell dissect between the collagen bundles were seen in 6 cases, malignant endothelial cells forming continuous sheets with epithelioid morphology in 3 cases, and mild vascular hyperplasia in 1 case. CD31 was positive on atypical endothelial cells in all patients. CONCLUSION: CAS should be included in differential diagnosis when cutaneous lesions show erythematous to purpuric nodule or patch with rapid progression on scalp or face of elderly patients. Histopathologically, CAS had wide spectrum from mild vascular hyperplasia to spindle cell tumors. As such, immunohistochemical stain, using endothelial markers, is valuable to diagnosis of CAS.
Age of Onset ; Aged ; Biopsy ; Carcinoma, Basal Cell ; Carcinoma, Squamous Cell ; Collagen ; Diagnosis, Differential ; Endothelial Cells ; Erysipelas ; Female ; Hemangiosarcoma ; Humans ; Hyperplasia ; Male ; Medical Records ; Scalp ; Skin Diseases