Background: Ecology, climate, atmosphere, human living conditions in the world are changing, and many factors affecting human health are both quantitative and qualitative changes, viruses and bacteria have evolved, and viruses that have never developed, including viral infections, are healthy . the medical and economic consequences of this disease are increasingly needed to study infectious diseases. We can consider the rich treasures of traditional medicine and the treatment of infectious diseases as an important source of many problems in the future. Therefore, in order to deepen the significance of traditional medicine and interpretative work, we set the goal to study the treatment of infectious diseases as an important theory and practice. Methods: The study group selected the 23-27th group for “The Four Roots of Medicine” and Tibetan, Mongolian 7 interpretations of the sages using the Comparison of reference and source studies” and Trial ranking, “Method of summation” were conducted. Results Treatment of infectious diseases fever is the very first. The Four Roots of Medicine was written with a detailed description of abdominal pain, hoarseness, heaviness and sweating, which have been reported recently and associated with infectious and febrile diseases, as well as the type of treatment. In addition, sources and explanations are important in theory and practice, which clearly identify problems with the treatment of infectious phases and diseases. On the therapeutic treatment of infectious diseases, this is the first written in the Four Roots of Medicine and the Golden Tassel in combination with incense and mantra treatment, as well as Lhanthav therapy and the most difficult treatment. It was originally written on the most famous invention such as “Enchantment’s of Ocean” by Jambalchoijidanzanperenlei, one of the wise men of Mongolia, which includes eight types of extravagant works, such as elves, sweat, rash, sweatshirts, weightlifting, incense, mantra and sucking elements.