1.Progress of sudden unexpected death in epilepsy.
Chinese Journal of Pediatrics 2014;52(11):828-830
Death, Sudden
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etiology
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Epilepsy
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complications
;
mortality
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Humans
2.Progress on the epidemiological study of epilepsy.
Yong ZHOU ; Min LIU ; Wan-nian LIANG
Chinese Journal of Epidemiology 2007;28(1):92-94
China
;
epidemiology
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Epilepsy
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complications
;
epidemiology
;
mortality
;
Humans
8.Treatment of obstructive sleep apnea-hypopnea with refractory epilepsy in children.
Da-bo LIU ; Shu-yao QIU ; Jian-wen ZHONG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2009;44(5):425-426
Child
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Child, Preschool
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Epilepsy
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complications
;
diagnosis
;
surgery
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Female
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Humans
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Male
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Sleep Apnea, Obstructive
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complications
;
diagnosis
;
surgery
9.Research advances in multimodal magnetic resonance for cognitive impairment in children with benign childhood epilepsy with centrotemporal spikes.
Lang-Zi TAN ; Li-Li LONG ; Bo XIAO
Chinese Journal of Contemporary Pediatrics 2020;22(5):528-532
Cognitive impairment in children with benign childhood epilepsy with centrotemporal spikes (BECT) has complex etiologies and is closely associated abnormal neural networks. Multimodal magnetic resonance imaging of brain structure and function is a powerful tool for studying abnormal neural networks of cognitive impairment in epilepsy and can explore the pathogenesis of cognitive impairment in epilepsy at the level of brain structure and function by analyzing the imaging features of brain structure and function. This article reviews the research advances in multimodal magnetic resonance for cognitive impairment in children with BECT.
Brain
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Child
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Cognitive Dysfunction
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complications
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Epilepsy, Rolandic
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complications
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Humans
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Magnetic Resonance Spectroscopy
10.Forensic Analysis of 9 Cases of Sudden Unexpected Death in Epilepsy.
Yu DU ; Guan-Ying HE ; Lei YAO ; Peng REN ; Li PANG ; Zhen-Yu ZHANG ; Wei-Dong WANG
Journal of Forensic Medicine 2022;38(4):490-494
OBJECTIVES:
To analyze the case, scene and forensic pathological characteristics of sudden unexpected death in epilepsy (SUDEP), to provide a practical basis for forensic identification.
METHODS:
A total of 9 autopsy cases of SUDEP were collected. The basic information of the cases, the scene characteristics, the forensic pathological changes, the common drugs and antiepileptic drug test results, and pericardial fluid biochemical test results were analyzed.
RESULTS:
All of the 9 cases were male epilepsy patients died during sleep at night, the age of death was (37.1±8.6) years, and the course of epilepsy was (21.3±5.6) years. Six corpses were in prone position and three in left lateral position. The hemorrhage of the sternocleidomastoid muscle, sternal thyroid muscle and sternohyoid muscle were found with 8 cases, 5 cases and 4 cases, respectively, all of them were unilateral. Six cases had bilateral hemorrhage of pectoralis minor muscle. Brain edema, phagocytosis of frontotemporal neurons and gliosis, cardiac fibers bend in wavy patterns and eosinophilic staining enhancement, pulmonary edema, pulmonary congestion, alveolar hemorrhage, pulmonary small bronchiole wall shrinking, tubular proteinuria and pancreatic parenchymal hemorrhage were the common histopathological changes. The biochemical test results of pericardial fluid indicated that there were myocardial ischemic damage.
CONCLUSIONS
Young male, early onset, long course of disease, sleep in the prone position, poor drug compliance or combination, epileptic seizure may be the risk factors of SUDEP. Cardiac dysfunction and respiratory depression might be the main death mechanism of SUDEP.
Humans
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Male
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Adult
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Middle Aged
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Female
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Sudden Unexpected Death in Epilepsy
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Death, Sudden/pathology*
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Epilepsy/complications*
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Forensic Medicine
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Forensic Pathology