1.Present Practice and Perspective of Evaluation and Surgery for Temporal Lobe Epilepsy.
Hans CLUSMANN ; Thomas KRAL ; Johannes SCHRAMM
Journal of Korean Neurosurgical Society 2005;38(3):165-183
Surgery for temporal lobe epilepsy refractory to medical treatment is a promising treatment option. After a short overview on historical developments in this field, we describe the present practice of presurgical evaluation and resection strategies as practiced at our institution and review the corresponding publications from other centers. We try to delineate major future developments for surgical therapy of temporal lobe epilepsy, as they can derived from present trends.
Epilepsy, Temporal Lobe*
;
Temporal Lobe*
2.Psychiatric morbidity in refractory mesial temporal lobe epilepsy before and after epilepsy surgery
Sawant Neena S ; Wankhede Shrikant S
Neurology Asia 2015;20(2):129-138
Background & Objective: Psychiatric disorders constitute a large part of illness burden in patients with
refractory epilepsy. A careful presurgical psychiatric assessment is now an integral part of evaluation
in most centers performing surgeries for refractory epilepsy. This study was undertaken to determine
the prevalence of psychiatric disorders and outcome of the psychopathology in patients of refractory
mesial temporal lobe epilepsy (mTLE) before and after epilepsy surgery. Method: Forty eight patients
diagnosed as having refractory mTLE by the Neurologists were included in the study. The patients
were assessed using the Brief Psychiatric Rating Scale (BPRS), Beck’s Depression Inventory (BDI),
Hamilton Depression Rating Scale (HDRS) and Hamilton Anxiety Rating Scale (HARS) before
surgery as well as in the second and sixth month of postoperative period. Results: More than half of
the patients (54%) had psychopathology. Depressive disorders were more common. Lateralisation of
focus in MTS and psychopathology in the patient revealed equal right and left preponderance. No
significant difference was found on BPRS, BDI and HDRS scales at 2 and 6 months follow up post
epilepsy surgery in patients having psychopathology.
Conclusions: Patients had a favourable outcome after surgery as regards to their psychopathology as
well as the seizures.
Epilepsy, Temporal Lobe
3.Postictal MR Enhancement in a Patient with Lateral Temporal Lobe Epilepsy.
Journal of the Korean Neurological Association 2012;30(1):72-73
No abstract available.
Epilepsy, Temporal Lobe
;
Humans
;
Temporal Lobe
4.Comparison of rCBF between Patients with Medial Temporal Lobe Epilepsy and Normal Controls using H215O PET.
Eun Joo KANG ; Jae Sung LEE ; Hyun Woo NAM ; Sang Kun LEE ; Dong Soo LEE ; June Key CHUNG ; Myung Chul LEE
Korean Journal of Nuclear Medicine 2002;36(3):155-165
No abstract available.
Epilepsy, Temporal Lobe*
;
Humans
;
Temporal Lobe*
6.Hemispheric laterality of temporal lobe epilepsy in relation to anxiety and depression.
Sang Jun KIM ; Chul LEE ; Youn Mee HWANG
Journal of Korean Neuropsychiatric Association 1993;32(3):343-349
No abstract available.
Anxiety*
;
Depression*
;
Epilepsy, Temporal Lobe*
;
Temporal Lobe*
7.A Novel Nonsense Mutation in Leucine-Rich, Glioma-Inactivated-1 Gene as the Underlying Cause of Familial Temporal Lobe Epilepsy.
Sumaira KANWAL ; Da Hye YOO ; Shahzad TAHIR ; Su Jung LEE ; Min Hee LEE ; Byung Ok CHOI ; Ki Wha CHUNG
Journal of Clinical Neurology 2018;14(4):591-593
No abstract available.
Codon, Nonsense*
;
Epilepsy, Temporal Lobe*
;
Temporal Lobe*
8.Three Patients with Nondominant Temporal Lobe Epilepsy Showing Ictal Spitting.
Chong Kyu CHU ; Kyoung HEO ; Min Kyung CHU ; Mi Hee LEE ; Soo Chul PARK ; Byung In LEE ; Jin Woo CHANG
Journal of Korean Epilepsy Society 2003;7(1):48-50
Spitting as an ictal phenomenon has rarely been reported. It is considered to indicate a seizure onset in the nondominant temporal lobe. Three cases with ictal spitting were found in 81 consecutive patients who underwent temporal lobe resections due to intractable temporal lobe epilepsy. Two had evidence of the right temporal ictal onset. One had the left temporal ictal onset, but the Wada test demonstrated language dominance in the right hemisphere. Three all had mesial temporal sclerosis. One had recollection of her episodes of spitting with a gustatory aura, whereas the other patients had no awareness of this symptom. These cases support previous studies suggesting that spitting is a lateralizing sign to nondominant temporal lobe epilepsy.
Epilepsy
;
Epilepsy, Temporal Lobe*
;
Humans
;
Sclerosis
;
Seizures
;
Temporal Lobe*
9.Clinical Correlations between Duration of Epilepsy and Anticonvulsant Treatment Response in Temporal Lobe Epilepsy.
Jin Woon PARK ; Jang Sung KIM ; Jae Hyeon PARK
Journal of the Korean Neurological Association 1996;14(2):433-439
We have studied the clinical correlations between duration of epilepsy and anticonvulsant treatment response in temporal lobe epilepsy. We evaluated correlations between the duration of epilepsy before control and frequencies after six and twelve months of antiepileptic drug treatment, respectively. And we analyzed differences of epilepsy duration between no recurrence group, reduced seizure frequencies below 25% of before control frequencies and reduced seizure frequencies above 25% of before control frequecies groups respectively. We concluded that there are no positive correlations between the duration of epilepsy and seizure frequencies after antiepileptic drug treatment (Spearman correlation coefficients 0.2801 p=0.354 at six months antiepileptic drug treatment, 0.2797 p=0.355 at twelve months). We also concluded that there are no differencies of epilepsy duration between no recurrence group, group with reduced seizure frequencies below 25% of before control frequencies and group with reduced seizure frequencies above 25% of before control frequecies after six months of antlepileptic drug treatment(p=0.6511)and after twelve months of antiepileptic drug treatment (p=0.9469).
Epilepsy*
;
Epilepsy, Temporal Lobe*
;
Recurrence
;
Seizures
;
Temporal Lobe*
10.Increased Corpora Amylacea in the Intractable Temporal Lobe Epilepsy: Case Report.
Ki Young CHOI ; Eun Jeong KOH ; Ha Young CHOI
Journal of Korean Neurosurgical Society 2003;34(1):61-64
Hippocampal sclerosis is the most common abnormal pathologic substrate found in patients with intractable temporal lobe epilepsy. Histopathological findings of hippocampal sclerosis are characterized by the presence of neuronal cell loss and astrocytic proliferation in the facsia dentata, Ammon's horn, presubiculum, and subiculum. Despite numerous studies having been conducted, the pathogenesis of hippocampal sclerosis is still controversial. Recently, it has been reported that increased numbers of corpora amylacea can be found in the hippocampus, the gray and white matter of the temporal lobe, in association with hippocampal sclerosis, which may give another clue to the pathogenesis of the hippocampal sclerosis. The authors report 3 patients with medically intractable temporal lobe epilepsy with hippocampal sclerosis in association with an increased numbers of corpora amylacea in the temporal white matter.
Epilepsy
;
Epilepsy, Temporal Lobe*
;
Hippocampus
;
Humans
;
Neurons
;
Sclerosis
;
Temporal Lobe*