2.Eosinophilic Cellulitis (Wells' Syndrome).
Korean Journal of Pathology 1995;29(3):407-410
Eosinophilic cellulitis is a rare dermatosis first described by Wells, and characterized by recurrent episodes of sudden outbreaks of erythematous cutaneous swellings often painful or pruritic. Microscopically, the lesion shows diffuse tissue eosinophilia and fibrinoid flame figures, evolution of associated focal necrobiosis, and formation of focal microgranulomas associated with eosinophils. The cause is still unknown but the triggers which have been thought to precipitate the disease include insect bites, parasitic infections such as toxocara, onchocerciasis, nasopharyngeal carcinoma, rheumatoid arthritis and spider bites. However many cases are idiopathic. The author experienced a case of eosinophilic cellulitis of a 52-year-old woman with multiple cutaneous tender plaques of cellulitis for approximately 10 years with history of repeated remission and recurrent episodes. Biopsy was taken from ulcerated edematous nodule of inguinal region under the clinical impression of deep fungal infection, pyoderma gangrenosum and polyarteritis nodosa. Cultures for fungal and common organisms were negative. Histologically, the entire dermis was infiltrated by numerous eosinophils and scattered histiocytes. There were scattered flame figures showing necrobiotic foci in the collagen with accumulation of eosinophils, granulated free cosinophilic granules and histiocytes.
Biopsy
;
Cellulitis/pathology*
;
Cellulitis/therapy
;
Eosinophilia/pathology*
;
Eosinophilia/therapy
;
Female
;
Humans
;
Middle Aged
3.Eosinophilic Cellulitis (Wells' Syndrome).
Korean Journal of Pathology 1995;29(3):407-410
Eosinophilic cellulitis is a rare dermatosis first described by Wells, and characterized by recurrent episodes of sudden outbreaks of erythematous cutaneous swellings often painful or pruritic. Microscopically, the lesion shows diffuse tissue eosinophilia and fibrinoid flame figures, evolution of associated focal necrobiosis, and formation of focal microgranulomas associated with eosinophils. The cause is still unknown but the triggers which have been thought to precipitate the disease include insect bites, parasitic infections such as toxocara, onchocerciasis, nasopharyngeal carcinoma, rheumatoid arthritis and spider bites. However many cases are idiopathic. The author experienced a case of eosinophilic cellulitis of a 52-year-old woman with multiple cutaneous tender plaques of cellulitis for approximately 10 years with history of repeated remission and recurrent episodes. Biopsy was taken from ulcerated edematous nodule of inguinal region under the clinical impression of deep fungal infection, pyoderma gangrenosum and polyarteritis nodosa. Cultures for fungal and common organisms were negative. Histologically, the entire dermis was infiltrated by numerous eosinophils and scattered histiocytes. There were scattered flame figures showing necrobiotic foci in the collagen with accumulation of eosinophils, granulated free cosinophilic granules and histiocytes.
Biopsy
;
Cellulitis/pathology*
;
Cellulitis/therapy
;
Eosinophilia/pathology*
;
Eosinophilia/therapy
;
Female
;
Humans
;
Middle Aged
4.Two cases of neck region Kimura's disease.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2015;29(11):1042-1043
Kimura's disease is a rare, benign, slow-growing chronic inflammatory swelling with a predilection for the head and neck region and is almost always with peripheral blood eosinophilia and elevated serum IgE levels. It is endemic in Asian males and rare in Western people. Surgical excision of the lesion is the first line therapy. Drug and radiation therapy have to be considered for the refractory lesions.
Angiolymphoid Hyperplasia with Eosinophilia
;
diagnosis
;
Asian Continental Ancestry Group
;
Eosinophilia
;
pathology
;
Humans
;
Immunoglobulin E
;
blood
;
Inflammation
;
pathology
;
Male
;
Neck
;
pathology
6.A case report of Kimura disease.
Xia WANG ; Jia SHEN ; Wei-Lan WU ; Min-Jiang WEI
Chinese Journal of Contemporary Pediatrics 2011;13(4):356-357
7.Chronic eosinophilic pneumonia with mucous plugs: case report.
Li-xin XIE ; Guo-xin MO ; Liang-an CHEN ; You-ning LIU
Chinese Medical Journal 2006;119(3):262-264
Adult
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Chronic Disease
;
Female
;
Humans
;
Mucus
;
Pulmonary Eosinophilia
;
metabolism
;
pathology
8.Clinicopathologic study of Churg-Strauss syndrome.
Rui-e FENG ; Hong-rui LIU ; Zhi-yong LIANG ; Ju-hong SHI ; Yuan-jue ZHU ; Dong-ge MU ; Hui-xing KE ; Ji-yao YU
Chinese Journal of Pathology 2008;37(2):114-117
OBJECTIVETo study the clinical and pathologic features of Churg-Strauss syndrome (CCS).
METHODSThree cases of Churg-Strauss syndrome, including 1 autopsy case and 2 cases with open thoracoscopic lung biopsy, were retrospectively reviewed. All the tissue samples were formalin-fixed, paraffin-embedded and stained with hematoxylin and eosin.
RESULTSThe first patient was a 68-year-old man who had history of asthma for 4 years, with recent exacerbation and chest pain for 2 weeks. Patient died 1 day after admission due to myocarditis and myocardial infarction. He did not have peripheral eosinophilia, skin or paranasal sinus pathology. CSS represented an incidental autopsy finding and he had never been treated with corticosteroid before. The other 2 patients were a 58-year-old male and a 12-year-old female, respectively. Both had history of asthma, peripheral eosinophilia and lung consolidations on computed tomographic examination. Pathologically, all cases showed vasculitis, perivascular allergic-type granulomas, eosinophilic pneumonia and asthmatic bronchitis.
CONCLUSIONSThorough understanding of the clinical and pathologic criteria is essential for arriving at a correct diagnosis of CSS. Although some patients may present with atypical symptoms, lung biopsies often reveal the classic histologic findings which include vasculitis and perivascular allergic granuloma formation.
Aged ; Churg-Strauss Syndrome ; pathology ; Eosinophilia ; pathology ; Female ; Granuloma ; pathology ; Humans ; Lung Diseases ; pathology ; Male ; Middle Aged ; Pulmonary Eosinophilia ; pathology ; Vasculitis ; pathology
9.Eosinophilic myositis in a slaughtered Korean native cattle.
Sun Hee DO ; Da Hee JEONG ; Jae Yong CHUNG ; Jin Kyu PARK ; Hai Jie YANG ; Dong Wei YUAN ; Kyu Shik JEONG
Journal of Veterinary Science 2008;9(4):425-427
Histopathological findings of eosinophilic myositis in the carcass of a slaughtered Korean native cow are presented. Lesions contained massive fibrous septae with vacuolar changes in some lesions, and the hypercontraction and rupturing of muscle bundles, with replacement by eosinophils. Necrosis and severe eosinophil infiltration were observed. Sarcoplasmic fragmentation and atrophy developed. Typical of granuloma, calcified myofibers were focally surrounded by macrophages and numerous inflammatory cells, and multinucleated giant cell formation was evident.
Animals
;
Cattle
;
Cattle Diseases/*pathology
;
Eosinophilia/pathology/*veterinary
;
Female
;
Muscle, Skeletal/*pathology
;
Muscular Diseases/pathology/*veterinary
10.Eosinophilic Liver Abscess.
The Korean Journal of Hepatology 2005;11(2):176-179
No abstract available.
Eosinophilia/*pathology
;
Humans
;
Liver/*pathology
;
Liver Abscess/*pathology
;
Male
;
Middle Aged