1.Clinical study on treatment of obsessive compulsive neurosis by acupoint stimulating control.
Bin FENG ; Lan-ying LIU ; Fang-zhong XU ; Jiong CHEN ; Peirong WANG ; Wensong CHEN ; Enyan YU
Chinese Journal of Integrated Traditional and Western Medicine 2005;25(9):801-803
OBJECTIVETo study the clinical effect of acupoint stimulating control (ASC) in treating obsessive compulsive neurosis.
METHODSThe comparative study was conducted in 65 patients with obsessive compulsive neurosis, they were divided into two groups, the 33 patients in the control group treated with chlorimipramine and the 32 in the tested group treated with ASC. The therapeutic efficacy and adverse reaction were assessed according to the standard for clinical efficacy evaluation by Yale-Brown scale for obsession (Y-BOCS)and adverse reaction scale.
RESULTSThe curative rate and markedly effective rate in the control group was 24.2% (8/33) and 27.3% (19/33), which in the tested group was 37.5% (12/32) and 34.4% (11/32) respectively. Significant difference was shown in comparison of Y-BOCS score between the two groups from the end of the 4th week of treatment (P < 0.05), indicating the efficacy in the tested group was better than that in the control group. Moreover, the occurrence of adverse reaction was higher in the control group than that in the tested group.
CONCLUSIONASC is a treatment with good effect, less adverse reaction and favourable safety superior to the treatment by chlorimipramine.
Acupuncture Points ; Adolescent ; Adult ; Aged ; Behavior Control ; methods ; Behavior Therapy ; Clomipramine ; therapeutic use ; Female ; Humans ; Male ; Middle Aged ; Obsessive-Compulsive Disorder ; therapy ; Psychiatric Status Rating Scales ; Transcutaneous Electric Nerve Stimulation ; methods
2.Research progress on epigallocatechin-3-gallate in the prevention and treatment of oral cancer
LIU Enyan ; HE Bing ; LI Mingyun
Journal of Prevention and Treatment for Stomatological Diseases 2020;28(7):468-471
Epigallocatechin-3-gallate (EGCG) has antibacterial, anti-inflammatory, antitumor, and other functions. EGCG and its anticancer mechanism are hot research topics in the prevention and treatment of oral cancer. In this paper, the prevention and treatment effects of EGCG on oral cancer and its anticancer mechanism are reviewed. The results show that EGCG can regulate multiple cell metabolic signaling pathways, such as the G protein coupled receptor signaling pathway, mitogen-activated protein kinase (MAPK), and the Wnt signaling pathway, and it can regulate DNA methylation and act on RNA of oral cancer cells directly or indirectly through the oral cancer cell signal transduction network to inhibit the development of oral precancerous lesions and oral cancer. EGCG combined with 5-fluorouracil can enhance the curative effect and reduce adverse effects and is expected to be a new drug for the prevention and treatment of oral cancer.
3.Research progress of laser in the treatment of intra-oral halitosis
Enyan LIU ; Shimeng XIAO ; Yi DING
Journal of Practical Stomatology 2024;40(4):561-567
Halitosis is one of the most common reason for referral to dentists following dental caries and periodontal diseases.80%to 90%of pathological halitosis is caused by oral factors,known as intra-oral halitosis(IOH).The clinical treatment of IOH includes regular dental cleaning,daily health care and the use of antibacterial drugs.However,these methods can not eradicate IOH,and the poor efficacy and strong discomfort of patients lead to poor compliance of them and the ideal control effect can not be achieved.Laser treatment,usually without anesthesia and almost no pain,is suitable for the clinical treatment of a variety of oral diseases.This review briefly introduces the eti-ology,diagnosis and treatment of IOH and focuses on the efficacy of laser treatment of IOH in recent years,providing more new options for the treatment of oral bad breath in the future.
4.Correction to: Comprehensive Management of Daily Living Activities, behavioral and Psychological Symptoms, and Cognitive Function in Patients with Alzheimer's Disease: A Chinese Consensus on the Comprehensive Management of Alzheimer's Disease.
Jianjun JIA ; Jun XU ; Jun LIU ; Yongjun WANG ; Yanjiang WANG ; Yunpeng CAO ; Qihao GUO ; Qiuming QU ; Cuibai WEI ; Wenshi WEI ; Junjian ZHANG ; Enyan YU
Neuroscience Bulletin 2022;38(3):337-338