2.Enterovirus Infection in Adults Presenting with Nonspecific Febrile Illness during Summer.
Areum DUREY ; Young Su JE ; Hea Yoon KWON ; Jae Hyoung IM ; Ji Hyeon BAEK ; Sun Myoung LEE ; Young Kyoung PARK ; Jin Soo LEE
Infection and Chemotherapy 2017;49(2):140-141
No abstract available.
Adult*
;
Enterovirus Infections*
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Enterovirus*
;
Humans
4.Enteroviruses isolated in patients with acute respiratory infections
Thanh Thi Hien Nguyen ; Van Thi Thanh Trieu
Journal of Preventive Medicine 2007;1(17):10-14
Background: at present, some enterovirus also was considered causes of acute respiratory infections in children. In Vietnam, no studies were published on the enteroviruses causing acute respiratory infections in humans. The research results would contribute to control and prevention of respiratory tract infections. Objectives: to identify enteroviruses causing acute respiratory infection syndrome in children. Subjectives and Method: a descriptive, prospective study, virus isolation. 185 samples of patients with acute respiratory tract infections, collected from both private clinics and from Dak Lak provincial general hospital, in 2004. Cells: RD, Hep2, L20B, and Vero provided by the World Health Organization (WHO). Antisera for diagnosing enteroviruses, antisera for diagnosing adenoviruses: A1-A7. Results: the results showed that 10.8% were positive with enteroviruses. These isolated enteroviruses consist of 13 Coxsackievirus B, 1 Echovirus, 1 Poliosabin type 1, and 5 untyped Enteroviruses. The result also showed that 8.1% of isolated viruses were Adenoviruses. Enteroviruses isolated mainly in September, followed by in February and in July accounted for 60% of isolated viruses. Conclusions: enteroviruses may be one of causes of respiratory infections in children. Some viruses had been isolated in the study such as: Coxsackievirus B, Echovirus, Poliosabin type 1, and untyped Enteroviruses.
Enterovirus/isolation &
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purification
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Enterovirus Infections/virology
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Respiratory Tract Infections/ virology
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5.Epidemiological characteristics of hand, foot and mouth disease among people aged 6 and over in Beijing, 2011-2020.
Shuai Bing DONG ; Xiao Li WANG ; Da HUO ; Ren Qing LI ; Yang YANG ; Zhi Chao LIANG ; Quan Yi WANG ; Lei JIA
Chinese Journal of Epidemiology 2022;43(2):207-212
Objective: To analyze the epidemiological characteristics of hand, foot and mouth disease (HFMD) among people ≥6 years old in Beijing from 2011 to 2020. Methods: The incidence data of HFMD cases from 2011 to 2020 were collected from the National Notifiable Infectious Disease Reporting System of China Information for Disease Control and Prevention and the etiological surveillance of HFMD in 29 sentinel hospitals from 16 districts of Beijing. Descriptive epidemiological methods were used to analyze the distributions, pathogen constituents, and changes of HFMD cases in Beijing people ≥6 years old. Results: From 2011 to 2020, a total of 38 183 cases of HFMD were reported among people ≥6 years old in Beijing, of which 46 (0.12%) cases were severe. The average annual reported incidence was 19.04/100 000. The ratio of males to females were 1.37∶1(22 064∶16 119). The proportion of HFMD in people ≥6 years old increased from 7.56%(2 606/34 488) in 2011 to 24.54% (546/2 225) in 2020. The average incidence of HFMD was higher in Shunyi district, Yanqing district, and Tongzhou district than in other districts in Beijing. The positive rate of enterovirus in sentinel surveillance was 66.78% (1 976/2 959), the proportion of enterovirus group A 71 (EV-A71) was 45.29% (101/223) in 2014, no EV-A71 positive was detected in 2020, and the proportion of Coxsackievirus A 6 (CV-A6) increased from 15.11% (34/225) in 2016 to 81.08% (60/74) in 2020. Conclusions: From 2011 to 2020, the proportion of cases with HFMD in people ≥6 years old in Beijing increased yearly, and the proportion of EV-A71 positive patients decreased basically. Since 2016, CV-A6 has gradually become the dominant pathogen. More attention should be paid to the epidemic situation and dynamic pathogen changes of hand foot mouth disease in people ≥6 years old.
Child
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China/epidemiology*
;
Enterovirus
;
Enterovirus A, Human
;
Enterovirus Infections/epidemiology*
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Female
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Hand, Foot and Mouth Disease/epidemiology*
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Humans
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Infant
;
Male
6.Chest X-ray findings in children with enterovirus 71 infection.
Wei-Hua ZHENG ; Xiong LI ; Fang-Yuan YANG ; Xin WANG ; Juan PENG ; Wei-Lin OU
Chinese Journal of Contemporary Pediatrics 2012;14(6):434-436
OBJECTIVETo study the characteristics of the chest X-ray images in children infected with enterovirus 71.
METHODSA total of 120 children with enterovirus 71 infection between April, 2010 and July, 2011 were classified into three groups according to the disease condition: mild (31 cases), severe (43 cases) and life-threatening (46 cases). The period from the onset of clinical symptoms to the first chest X-ray imaging examination and the results of the first chest X-ray findings were compared among the three groups.
RESULTSThe period from the onset of clinical symptoms to the first chest X-ray imaging examination in the mild, severe and life-threatening groups was 26-48 hrs (median 37 hrs), 10-36 h (median 23 hrs) and 2-36 hrs (median 19 hrs) respectively. Chest X-ray abnormalities were initially observed at 30 hrs after the onset of clinical symptoms in the mild group, at 23 hrs in the severe group and at 2 hrs in the life-threatening group (P<0.01). The mild group presented an initial imaging abnormality rate of 5.8%, the severe group 81.3% and the life-threatening group 100%. The life-threatening group showed a significantly higher initial X-ray abnormality rate than the other two groups (P<0.01). In terms of chest X-ray performance, the mild group usually presented lung marking thickening or vagueness. Most children in the severe group presented lung effusion and consolidation. Signs of pulmonary edema were found in the life-threatening group, and lesions in the life-threatening group were characterized by wide distribution and many lung lobe involvements.
CONCLUSIONSThe interval between the onset of clinical symptoms and the initial chest X-ray examination, the period of time of, and the onset of clinical symptoms, at which chest X-ray abnormalities, the abnormality rate and the severity of chest X-ray findings may be paralleled to the clinical situation in children with enterovirus 71 infection.
Child, Preschool ; Enterovirus A, Human ; Enterovirus Infections ; diagnostic imaging ; Female ; Humans ; Infant ; Male ; Radiography, Thoracic
7.Study on the molecular typing and epidemiology of non-polio enteroviruses isolated from Yunnan province, China.
Bing-jun TIAN ; Yan WU ; Dong-hua ZHANG ; Li-fang HE ; Zheng-rong DING ; Lin LU
Chinese Journal of Epidemiology 2007;28(4):346-349
OBJECTIVEThis report presented an overview on the epidemiology of enterovirus in Yunnan province, the People's Republic of China.
METHODSA total of 210 strains of non-polioviruses isolated under acute flaccid paralysis surveillance during a 5-year study period from 1997 to 2000 and 2004 were examined. Of the 210 non-polioviruses strains, a total of 12 strains of adenoviruses were serologically identified. The remaining 198 isolates were used for molecular typing, and the viral genomes of 195 nonpolio enteroviruses (NPEVs) were translated to corresponding amino acid sequences and compared with those of the prototype strains.
RESULTSBased on molecular typing, 5 isolates were classified into 5 serotypes of human enterovirus A species while 158 isolates into 34 serotypes of B and 32 isolates into 6 serotypes of C species. However, we did not isolate any viruses which belonged to human enterovirus D species. Thus, under acute flaccid paralysis surveillance, human enterovirus B species accounted for 75.2% of the 210 isolates and was considered as the predominant one, followed by human enterovirus C (12.2%), adenovirus (5.7%), and human enterovirus A (2.4%).
CONCLUSIONAlthough the epidemiological characteristics of NPEVs from Yunnan province remained "unknown", the molecular typing method had provided us a breakthrough to understand the epidemiology of these viruses.
China ; epidemiology ; Enterovirus ; classification ; genetics ; isolation & purification ; Enterovirus Infections ; epidemiology ; Genes, Viral ; Humans ; Molecular Epidemiology ; Serotyping
10.Recent advances in reverse genetics of enterovirus 71.
Wei-Jun CAO ; Hai-Xue ZHENG ; Fan YANG
Chinese Journal of Virology 2011;27(6):609-613