1.Antibiotic-associated Pseudomembranous Colitis
Myung Chul YOO ; Dae Kyung BAE ; Bong Keun KIM ; Ki Young KIM ; Ihn Ghoo KIM
The Journal of the Korean Orthopaedic Association 1983;18(4):763-767
No abstract available in English.
Enterocolitis, Pseudomembranous
2.A case of amebic colitis mimicking pseudomembranous colitis.
Jee Young LEE ; Paul CHOI ; Hyo Keun BAE
Korean Journal of Medicine 2010;78(6):703-704
No abstract available.
Dysentery, Amebic
;
Enterocolitis, Pseudomembranous
;
Sigmoidoscopy
3.A Case of Pseudomembranous Colitis Associated with Neutrocytic Ascites.
Kyoung Sun NA ; Dae Won JUN ; Eun Joo PARK ; Woo Young JANG ; Yong Cheol JEON ; Chang Soo EUN ; Joo Hyun SOHN ; Dong Soo HAN
Korean Journal of Gastrointestinal Endoscopy 2000;21(1):568-571
Antibiotic associated colitis due to Clostridium difficile is a common infection associated with significant morbidity. In severe cases, Pseudomembranous colitis (PMC) may be associated with intraperitoneal fluid accumulation. Howwver, the characteristics of the liquid are seldom described. This case report describes PMC patients who were presented with low serum-ascites albumin gradients (SAAG)and neutrocytic ascites, without evidence of infectious, malignant, or inflammatory peritoneal disease. The characteristics of their fluid specimens and the possible pathogenic mechanisms are discussed. These findings suggest that PMC without bowel perforation or spontaneous bacterial peritonitis.
Ascites*
;
Clostridium difficile
;
Enterocolitis, Pseudomembranous*
;
Humans
;
Peritoneal Diseases
;
Peritonitis
4.Antibiotics Associated Hemorrhagic Colitis: A report of two cases.
Kwang An KWUN ; Jeong Ho HAM ; Eun Joo KIM ; Il Kwun CHUNG ; Hong Soo KIM ; Sang Heum PARK ; Moon Ho LEE ; Sun Joo KIM
Korean Journal of Gastrointestinal Endoscopy 2001;22(1):45-49
Antibiotics related colitis is a well recognized disease entity which in its severest form may result in pseudomembranous colitis, whereas in another form, acute hemorrhagic colitis without pseudomembrane, related to the use of penicillin-type antibiotics is rarely reported. The clinical features of hemorrhagic colitis associated with antibiotics was characterized that the bloody diarrhea, often with abdominal cramping pain begins 2~7 days after starting the antibiotics and rapidly recovered after its withdrawal. Pathogenesis of this disease is not entirely clear. It has been believed that right-sided hemorrhagic colitis is one of the main forms of colitis associated with antibiotics, especially ampicillin derivatives or cephalosporin, but recent reports presented left-sided colitis. We experienced 2 cases of hemorrhagic colitis developed on the left colon after the introduction of quinolone.
Ampicillin
;
Anti-Bacterial Agents*
;
Colic
;
Colitis*
;
Colon
;
Diarrhea
;
Enterocolitis, Pseudomembranous
5.Refractory Clostridium difficile Infection Cured With Fecal Microbiota Transplantation in Vancomycin-Resistant Enterococcus Colonized Patient.
Mi Ok JANG ; Jun Hwan AN ; Sook In JUNG ; Kyung Hwa PARK
Intestinal Research 2015;13(1):80-84
The rates and severity of Clostridium difficile infections, including pseudomembranous colitis, have increased markedly. However, there are few effective treatments for refractory or recurrent C. difficile infections and the outcomes are poor. Fecal microbiota transplantation is becoming increasingly accepted as an effective and safe intervention in patients with recurrent disease, likely due to the restoration of a disrupted microbiome. Cure rates of >90% are being consistently reported from multiple centers. We cured a case of severe refractory C. difficile infection with fecal microbiota transplantation in a patient colonized by vancomycin-resistant enterococcus.
Clostridium difficile*
;
Colon*
;
Enterococcus*
;
Enterocolitis, Pseudomembranous
;
Humans
;
Microbiota*
6.Clinical Characterization of Clostridium difficile Infection in Elderly Patients.
The Korean Journal of Gastroenterology 2016;67(2):61-63
No abstract available.
Aged
;
*Clostridium Infections
;
*Clostridium difficile
;
Diarrhea
;
Enterocolitis, Pseudomembranous
;
Humans
7.Esosinophilic Gastroenteritis with Clostridium difficile-associated Colitis: A Case Report.
Tae Gyoon KIM ; Jongha PARK ; Eun Hee SEO ; Hee Rin JOO ; Seung Ha PARK ; Tae Oh KIM ; Sung Yeon YANG ; Young Soo MOON
Korean Journal of Gastrointestinal Endoscopy 2011;43(1):64-68
Eosinophilic gastroenteritis is an uncommon disease characterized by eosinophilic infiltration in the bowel wall and presents various symptoms depending on the affected site and bowel layer. Pseudomembranous colitis is an antibiotic-associated infection caused by abnormal overgrowth of the toxin-producing Clostridium difficile in the large bowel. A 16-year-old boy was admitted with abdominal pain for 6 days. On admission, we performed an endoscopy and diagnosed gastroduodenitis. Then, we prescribed gastritis medication but he still presented with diffuse abdominal pain and fever above 38.0degrees C after admission. We considered infectious enterocolitis, so we prescribed an antibiotic. The next day, he presented with bloody diarrhea. A diagnosis of pseudomembranous colitis was confirmed by a colonoscopic examination with a biopsy. We also obtained a diagnosis of eosinophilic gastroenteritis through a histological diagnosis. This is the first case of the simultaneous occurrence of eosinophilic gastroenteritis and pseudomembranous colitis in the Korean medical literature. We report this case with a brief review of the literature.
Abdominal Pain
;
Adolescent
;
Biopsy
;
Clostridium
;
Clostridium difficile
;
Diarrhea
;
Endoscopy
;
Enteritis
;
Enterocolitis
;
Enterocolitis, Pseudomembranous
;
Eosinophilia
;
Eosinophils
;
Fever
;
Gastritis
;
Gastroenteritis
;
Humans
8.Two Cases of Refractory Pseudomembranous Colitis that Healed Following Fecal Microbiota Transplantation.
Tae Geun GWEON ; Myung Gyu CHOI ; Soon Kyu LEE ; Jeong Hoon HA ; Eun Young KIM ; Byoung Soung GO ; Sang Woo KIM
Korean Journal of Medicine 2013;84(3):395-399
The incidence, recurrence, and mortality of Clostridium difficile infection are increasing and the standard therapy is oral metronidazole or vancomycin. Since treatment failure with standard therapy is increasing, an alternative therapy is needed. Fecal microbiota transplantation is one effective method in patients with refractory or recurrent C. difficile infection, including pseudomembranous colitis. Here, we report two cases of refractory pseudomembranous colitis treated with fecal microbiota transplantation.
Clostridium difficile
;
Enterocolitis, Pseudomembranous
;
Humans
;
Incidence
;
Metagenome
;
Metronidazole
;
Recurrence
;
Transplants
;
Treatment Failure
;
Vancomycin
9.The role of flexible sigmoidoscopy in the diagnosis of Clostridium difficile-associated diarrhea.
Sae Hee KIM ; Sung Hee JUNG ; Yun Jung LEE ; Woo Jin HYEON ; Young Wook YOO ; Hyang Ie LEE ; Hyeon Woong YANG ; Anna KIM ; Sang Woo CHA
Korean Journal of Medicine 2010;78(3):318-324
BACKGROUND/AIMS: Clostridium difficile is an important cause of diarrhea in hospitalized patients. C. difficile-associated diarrhea (CDAD) is usually diagnosed following a stool test for C. difficile cytotoxin or stool culture for the presence of toxigenic C. difficile. However, the reported sensitivities of these tests are variable. Sigmoidoscopy may be an effective diagnostic method in patients with a false-negative stool test for cytotoxin. This study examined the role of flexible sigmoidoscopy in the diagnosis of CDAD. METHODS: Among the patients who had diarrhea and were examined with sigmoidoscopy in Eulji University Hospital between January 2005 and July 2008, 102 patients suspected of having antibiotic-associated diarrhea (AAD) based on their clinical symptoms were enrolled. Of the 102 patients, 74 were diagnosed with CDAD based on C. difficile cytotoxin or sigmoidoscopic findings of pseudomembranous colitis. The medical records of these 74 patients were reviewed retrospectively. RESULTS: Of the 74 patients, sigmoidoscopic findings revealed a pseudomembrane in 63 patients (85.1%) and colitis in nine (12.2%), while two patients (2.7%) appeared normal. Of the 63 patients with pseudomembranous colitis at sigmoidoscopy, the stool C. difficile cytotoxin assay was negative in 27 (42.9%). CONCLUSIONS: Flexible sigmoidoscopy was highly sensitive in pseudomembranous colitis and is useful in diagnosing patients with a delayed or negative stool test for C. difficile cytotoxin. Therefore, we recommend flexible sigmoidoscopy in patients suspected of having C. difficile-associated diarrhea for the diagnosis of CDAD.
Clostridium
;
Clostridium difficile
;
Colitis
;
Diarrhea
;
Enterocolitis, Pseudomembranous
;
Humans
;
Medical Records
;
Sigmoidoscopy
10.The Relationship between Endoscopic Degrees and Prognostic Factors in Pseudomebranous Colitis.
Jeong Hoon PARK ; Won Yeop BAE ; Jae Hak LEE ; Do Hyun PARK ; Suck Ho LEE ; Il Kwun CHUNG ; Sang Heum PARK ; Sun Joo KIM
Korean Journal of Gastrointestinal Endoscopy 2006;32(4):260-265
BACKGROUND/AIMS: Leukocytosis and hypoalbuminemia are known to be poor prognostic factors. The aim of this study was to determine how the leukocyte counts and albumin level are related to the colonic endoscopic findings. METHODS: Fifty three pseudomembranous colitis (PMC) patients confirmed by a lower endoscopy were analyzed. Endoscopic degree of pseudomembranous plaque was classified into four grades. The endoscopic severity was classified into two groups (group A: G I~II, group B: G III~IV). RESULTS: The mean age was 64.9 years, the mean onset of diarrhea after exposure to antibiotics was 12.9 days, the reasons for admission were medical (58.5%, 31) and surgical (41.5%, 22). Frequently the causative antibiotic was cephalosporin (81.1%, 43/53), and the mean WBC counts and albumin level were 13,045/mm3 and 3.13 g/dL, respectively. The endoscopic degrees of PMC was grade I (9.4%, 5), grade II (32.1%, 17), grade III (41.5%, 22), and grade IV (17%, 9). The patients' WBC counts and albumin level were not associated with the endoscopic severity. The age, gender, causative antibiotics, diabetes showed no correlation. CONCLUSIONS: There were no correlations between the known poor clinical prognostic factors (leukocystosis and hypoalbuminemia) and the endoscopic severity.
Anti-Bacterial Agents
;
Colitis*
;
Colon
;
Diarrhea
;
Endoscopy
;
Enterocolitis, Pseudomembranous
;
Humans
;
Hypoalbuminemia
;
Leukocyte Count
;
Leukocytosis