The septicemia caused by the Arizona group organism is rare and usually observed in adults with underlying diseases. In Korea, Salmonella infection is common, but a report of Arizona infection is unknown. We isolated S. entercia subsp. diarizonae from blood of a 6-month-old infant. The serovar was determined as 28:z10:-, a rare one in America. The isolate was susceptible to ampicillin, chloramphenicol, cotrimoxazole and others. The patient rapidly recovered with ampicillin and gentamicin therapy. Clinical laboratories should consider that the infection exists in Korea and should attempt to isolate and identify Arizona organism in certain patients.
Bacteremia/*microbiology ; Case Report ; Enteritis/*microbiology ; Human ; Infant ; Korea/epidemiology ; Male ; *Salmonella Infections ; *Salmonella arizonae

Pigbel remains a likely significant cause of morbidity and mortality in the highlands of Papua New Guinea (PNG), two decades after the administration of pigbel vaccination ceased. There is a need for an effective surveillance program for pigbel to better understand the disease burden and to target communities for preventive strategies. This paper reviews the epidemiology, pathogenesis, recent history and current data on the burden of pigbel in PNG. We propose a surveillance program based on clinical recognition of likely cases and laboratory confirmation using an ELISA assay for Clostridium perfringens type C beta-toxin. Research aimed at validating this approach in the clinical setting is outlined.
Clostridium Infections/epidemiology/*microbiology/*prevention & control ; Clostridium perfringens/pathogenicity ; Enteritis/epidemiology/*microbiology/*prevention & control ; Health Services Needs and Demand ; Humans ; Incidence ; Papua New Guinea/epidemiology ; Population Surveillance

A total of 74 isolates of Salmonella enterica serovar London were collected through the Laboratory-Based Diarrheal Diseases Surveillance in 2000-2001. In order to characterize the isolates and investigate the source of the epidemic, we performed antimicrobial susceptibility tests and XbaI Pulsed-field gel electrophoresis (PFGE) of 44 Salmonella London isolates. Forty isolates were from feces of infants and four isolates were from adults aged 30, 52, 54, and 59 yr. Two subtypes were identified: a tetracycline-susceptible A 0 PFGE pattern and a tetracyclineresistant A 1 PFGE pattern. Interestingly, the isolates from all infants and one 30-yr-old adult were A 0 PFGE pattern and tetracycline-susceptible. Furthermore, the A 0 PFGE pattern strain was approximately 2 times more virulent than the A 1 PFGE pattern strain, according to the results of in vitro invasion assay using J774A.1 macrophage-like cells. These results indicate that the active surveillance with molecular epidemiological tools would be valuable for promptly finding new epidemic strains. Our results also suggested that the virulent Salmonella London strain might infect the infants through a common contaminated source.
Adult ; Anti-Bacterial Agents/therapeutic use ; DNA, Bacterial/analysis ; Diarrhea/epidemiology/microbiology ; Disease Outbreaks ; Enteritis/*epidemiology/microbiology ; Feces/microbiology ; Human ; In Vitro ; Infant ; Microbial Sensitivity Tests ; Middle Aged ; Reactive Oxygen Species/pharmacology ; Salmonella Infections/drug therapy/*epidemiology/microbiology ; Salmonella enterica/genetics/*isolation & purification/pathogenicity ; Virulence

Porcine proliferative enteropathy(PPE) is an enteric disease been caused by Lawsonia intracellularis. It has become one of the critical problems in the pig industry. To investigate the prevalence of PPE in Korea, serum samples of 828 pigs from 65 herds were tested using indirect immunofluorescence antibody technique(IFA). The infection rate in individual pigs varied from 44 to 69%, whereas 100% in pig farms. The infection frequency was 57, 44.9, and 59.4% according to age respectively. Administration of tylosin in feed at a concentration of 110 ppm for 14 days reduced the infection rate of the farms. These data indicated that the high prevalence of PPE may be controlled by tylosin.
Administration, Oral ; Animal Feed ; Animals ; Anti-Bacterial Agents/*therapeutic use ; Antibodies, Bacterial/blood ; Enteritis/epidemiology/prevention&control/*veterinary ; Fluorescent Antibody Technique, Indirect/veterinary ; Gram-Negative Bacterial Infections/prevention&control/*veterinary ; Korea/epidemiology ; *Lawsonia Bacteria/drug effects/growth&development/immunology ; Seroepidemiologic Studies ; Swine ; Swine Diseases/*epidemiology/microbiology/prevention&control ; Tylosin/*therapeutic use