1.Advanced research on characteristics of the classical subtype of human glioblastoma
Enrui LIU ; Huan REN ; Yu ZHAO ; Jun SU
Practical Oncology Journal 2015;(2):136-139
Glioblastoma(GBM)is one of the most common primary intracranial tumor that has high de-gree of malignancy ,invasive ability and a fatal prognosis .In recent years ,with the development of modern technol-ogy in biomedical sciences ,the understanding on GBM has developed gradually from pathological diagnosis to mo -lecular classifications ,which is based on the molecular characteristics of genetic signatures .Based on gene expres-sion and DNA methylation patterns , primary glioblastoma is divided into four subtypes , including the classical , neural,proneural and mesenchymal .These molecular classifications are closely relevant to the biological charac-teristics of glioblastoma .This review briefly introduces the molecular classifications of primary glioblastoma , but mainly focuses on the changes of the major genetic EGFR ,PTEN and PI3K,CDKN2A in the classical subtype of GBM,and discusses the treatment strategies for primary glioblastoma .
2.Natural orifice specimen extraction surgery (NOSES) for colon cancer treatment: a double-center case-matched study of surgical and short-term postoperative outcomes.
Petr TSARKOV ; Zheng LIU ; Albina ZUBAYRAEVA ; Anastasia MARCHUK ; Grigoriy KOROLEV ; Enrui LIU ; Xishan WANG ; Sergey EFETOV
Chinese Medical Journal 2023;136(10):1234-1236