1.Adult wilms tumor with extra-axial cerebral extension: Case report and review of literature.
Neddy L. Lim ; Enrique Ian Lorenzo ; Juan Godofredo Bardelos ; Edgardo L. Reyes ; Nelson A. Patron
Philippine Journal of Urology 2022;32(2):78-83
Wilms tumor is very rare in adults. Even more infrequent is an adult Wilms tumor with an extensioninto the central nervous system.Reported here is a case of an adult Wilms tumor in a 38-year-old female. She was referred to theJRRMMC with a 2 month history of intermittent hematuria associated with a rapidly enlargingabdominal mass and right-sided facial asymmetry. Abdominal computed tomography revealed a largemass inthe rightkidney. CranialMRI showedmultiple brainmetastases. Thepatient underwentrightradicalnephrectomy.Pathologicalanalysisdemonstratednephroblastoma.Thepatientwasdischargedunremarkable and underwent adjuvant chemotherapy. After 2 months, the patient succumbed to thedisease.Adult Wilms tumor presents almost similarly with renal cell carcinoma and there is no definitivediagnostictesttoconfirmitpre-operatively.Eventhoughit’sararetumor,itshouldalwaysbeincludedin the differential diagnosis for any renal tumor.
2.En bloc prostatectomy combined with abdominoperineal resection on locally advanced rectal adenocarcinoma involving the prostate: A case series
Hansel Shehaila A. Lastrilla ; Enrique Ian S. Lorenzo
Philippine Journal of Urology 2024;34(1):20-25
Abstract:
The genitourinary tract is known to be infiltrated in 3–10% of cases of advanced rectal adenocarcinoma. It is usually managed with total pelvic exenteration with urinary diversion. Complications are encountered because of this diversion. This case series aims to present four cases of locally advanced rectal adenocarcinoma involving the prostate who underwent en bloc prostatectomy in Jose Reyes Memorial Medical Center.
Methods:
This case series consists of review of records of hospital charts, documentation of specimens from the database of the department.
Results:
The study consists of four (4) male patients in their 50s presenting with primary rectal adenocarcinoma with invasion to the prostate, bladder or seminal vesicle. Two out of 4 patients had shorter hospital days (6 days) while 2 patients spent 14 and 28 days. Two out of 4 patients have anastomotic leakage, 1 had nosocomial pneumonia and no one had urinary tract infection, postoperatively. All 4 patients had a histopathologic diagnosis of rectal adenocarcinoma with a tumor size of 3.5 to 7.0 cm. Two patients are positive for lymphovascular space invasion while 1 patient has a positive line of resection margin. Two patients had neoadjuvant chemotherapy and radiotherapy while 1 patient had 1 adjuvant chemotherapy and radiotherapy. One patient was lost to follow-up.
Conclusion
En bloc prostatectomy combined with abdominoperineal resection to treat locally advanced rectal adenocarcinoma provides good local control with the risk of having less postoperative complications. Since there is only one stoma, there is less chance of infection and better quality of life. Complete resection of the tumor can be obtain but can also cause urologic morbidity even after chemotherapy and radiotherapy.
Proctectomy
3.A retrospective study on retrograde Intra-renal Surgery with versus without the use of Ureteral Access Sheaths in patients with Nephrolithiasis.
Christine Joy G. Castillo ; Enrique Ian Lorenzo
Philippine Journal of Urology 2023;33(1):5-11
INTRODUCTION:
Placement of ureteral access sheath (UAS) prior to retrograde intra-renal surgery (RIRS)
is done to provide easier re- entries, shorter operation time and better vision. However, some studies
have associated the placement of UAS to increased morbidity and complications.
OBJECTIVE:
The study aimed to compare outcomes of patients with nephrolithiasis who underwent
RIRS with versus without placement of UAS.
METHODS:
This is a retrospective cohort study among patients with nephrolithiasis who underwent
RIRS with or without placement of UAS. The authors analyzed a total of 52 patients who underwent
RIRS, 22 without, and 30 with UAS. Comparison of patients’ clinical profile, duration of post-operative
hospital stay and the difference of their frequency were determined using Independent Sample T-test,
Mann-Whitney U test and Fisher’s Exact test, respectively. STATA 15.0 was used for data analysis.
RESULTS:
The two groups were similar in terms of clinical profile and operative outcomes. In terms
of complications, there was one patient who had a failed surgery in the UAS group. Bleeding was
reported in both groups. One-fourth of the patients had abdominal/bladder cramps and 13% had
fever. Stone-free rate was 94% at 1 month and 92% at 3 months post-op. Readmission within 3 months
was seen in four patients (8%) and retreatment was done on three patients (6%).
CONCLUSION
There is no significant difference in placing UAS or not prior to RIRS in terms of clinical
profile and operative outcomes. Safety measures should be observed to prevent any bleeding and
ureteral injuries during placement of UAS intra-operatively.
4.JuRoLap: A resilient and economical home-made specimen retrieval bag.
Paul Nimrod B. Firaza ; Enrique Ian D. Lorenzo ; Ramon Jacinto A. Ursua ; Rajiv S. Kalbit ; Neddy L. Lim ; Juan Godofredo S. Bardelosa ; Nelson A. Patron ; Edgardo L. Reyes
Philippine Journal of Urology 2018;28(1):23-27
OBJECTIVE:
Specimen retrieval bags were used to remove cysts and masses in minimally invasiveurologic surgeries for more than 3 decades. This study aims to describe the steps in making a home-made specimen retrieval bag named JuRoLap and its safety and resiliency.
MATERIALS AND METHODS:
The bag’s name was taken from the initials of the institution combined withthe department's short-name (uro) and laparoscopy (Lap). The bag is composed of a non-toxicpolyvinyl chloride (PVC) urine bag custom fitted according to the expected specimen size. The sideswere sealed using an impulse sealer leaving one side open. The bag ways rolled and introducedintracorporeally via the 12mm port. It was opened followed by specimen placement using standardlaparoscopic instruments. Purse-string suture at the one-side opening was tightened and extractedthrough the umbilical port extending the incision as necessary.
RESULTS:
JuRoLap was used in 33 cases removing various organs such as adrenals, kidney, ureter,bladder and prostate. It was easily prepared, safe, resilient and economical costing approximatelyUSD 0.68. It was essential to routinely check its durability by doing a leak test prior to sterilization.Proper rolling, transparent plastic component of the bag and the use of two laparoscopic graspersprovided ease in bag deployment and specimen entrapment. It was also observed that smaller incisionon extraction site as compared to the specimen size was needed due to the resiliency of the bag.Despite the required learning curve in organ entrapment and extraction, there were no complicationsand specimen leakage noted.
CONCLUSION
JuRoLap specimen retrieval bag is organ size specific, safe, resilient and low cost specimenretrieval bag innovation.
Laparoscopy
5.Palpation Device for the Identification of Kidney and Bladder Cancer: A Pilot Study.
Jae Won LEE ; Enrique Ian S LORENZO ; Bummo AHN ; Cheol Kyu OH ; Hyung Joo KIM ; Woong Kyu HAN ; Jung KIM ; Koon Ho RHA
Yonsei Medical Journal 2011;52(5):768-772
PURPOSE: To determine the ability of a novel palpation device to differentiate between benign and malignant tissues of the kidney and bladder by measuring tissue elasticity. MATERIALS AND METHODS: A novel palpation device was developed, mainly composed of a micromotor, a linear position sensor, a force transducer, and a hemisphere tip and cylindrical body probe. Motion calibration as well as performance validation was done. The tissue elasticity of both benign and malignant tissues of the kidney and bladder was measured using this device. A single investigator performed the ex-vivo palpation experiment in twelve kidneys and four bladder specimens. Malignant tissues were made available from partial nephrectomy specimens and radical cystectomy specimens. Palpations for benign renal parenchyma tissue were carried out on nephroureterectomy specimens while non-involved areas in the radical cystectomy specimens were used for benign bladder samples. Elastic modulus (Young's modulus) of tissues was estimated using the Hertz-Sneddon equation from the experimental results. These were then compared using a t-test for independent samples. RESULTS: Renal cell carcinoma tissues appear to be softer than normal kidney tissues, whereas tissues from urothelial carcinoma of the bladder appear to be harder than normal bladder tissues. The results from renal cell carcinoma differed significantly from those of normal kidney tissues (p=0.002), as did urothelial carcinoma of the bladder from normal bladder tissues (p=0.003). CONCLUSION: Our novel palpation device can potentially differentiate between malignant and benign kidney and bladder tissues. Further studies are necessary to verify our results and define its true clinical utility.
Adult
;
Aged
;
Elastic Modulus
;
Elasticity Imaging Techniques/*instrumentation
;
Equipment Design
;
Female
;
Humans
;
Kidney/physiology
;
Kidney Neoplasms/*diagnosis/physiopathology
;
Male
;
Middle Aged
;
Palpation/*instrumentation
;
Phantoms, Imaging
;
Pilot Projects
;
Urinary Bladder/physiology
;
Urinary Bladder Neoplasms/*diagnosis/physiopathology
6.Initial Clinical Experience with Robot-Assisted Laparoscopic Partial Nephrectomy for Complex Renal Tumors.
Kyung Hwa CHOI ; Cheol Kyu OH ; Wooju JEONG ; Enrique Ian S LORENZO ; Woong Kyu HAN ; Koon Ho RHA
Korean Journal of Urology 2009;50(9):865-869
PURPOSE: Robot-assisted laparoscopic partial nephrectomy (RLPN) is gaining acceptance as an alternative to open partial nephrectomy and laparoscopic partial nephrectomy for small renal masses. However, it still remains a technically challenging procedure even for experienced laparoscopists. Endophytic tumors or renal hilar tumors pose an additional challenge. MATERIALS AND METHODS: We reviewed the medical records of 11 patients (mean age: 49.3 years; range: 31-67 years) who underwent RLPN for small, complex renal masses including hilar tumors and endophytic tumors. RLPN was performed with the Da Vinci(R) surgical system (Intuitive Surgical, Sunnyvale, USA) with three robot arms and intraoperative ultrasonography (Tile-pro(R) System). RESULTS: RLPN was performed successfully without complications in all cases. The mean tumor size was 3.2 cm (range, 1.1-8.0 cm). The mean operative time was 177 minutes (range, 150-260 minutes), and the mean warm ischemia time was 32 minutes (range, 25-41 minutes). The mean estimated blood loss was 177 ml (range, 50-350 ml), and the mean hospital stay was 4 days (range, 3-7 days). Pathology found four patients with clear cell type renal cell carcinoma, one with multilocular multicystic renal cell carcinoma, two with papillary type, one with chromophobe type, and three with angiomyolipoma. CONCLUSIONS: RLPN is a feasible and safe surgery for complex renal tumors. In our experiences, RLPN could be a nephron-sparing surgical option for patients with compromised renal function and it could be an alternative to open partial nephrectomy and laparoscopic partial nephrectomy for a select group of patients.
Angiomyolipoma
;
Arm
;
Carcinoma, Renal Cell
;
Humans
;
Kidney Neoplasms
;
Length of Stay
;
Medical Records
;
Nephrectomy
;
Operative Time
;
Robotics
;
Warm Ischemia
7.Iliac Vein Injury Due to a Damaged Hot Shearstrade mark Tip Cover During Robot Assisted Radical Prostatectomy.
Enrique Ian LORENZO ; Wooju JEONG ; Sangun PARK ; Won Tae KIM ; Sung Joon HONG ; Koon Ho RHA
Yonsei Medical Journal 2011;52(2):365-368
We report a rare case of vascular injury secondary to a damaged Hot Shearstrade mark tip cover. Two 1 mm holes in the tip cover resulted in perforations in the obturator and external iliac veins during pelvic node dissection. Bleeding was controlled with bipolar coagulation and a 5 mm metal clip in the obturator and iliac vein, respectively. The rest of the procedure was completed uneventfully. Frequent integrity assessment of this accessory is necessary. Its function is important in order to carry out safe dissection in proximity to delicate structures. When injuries arise from areas not directly involved in the dissection, immediate inspection of the instruments should be mandatory.
Humans
;
Iliac Vein/*injuries
;
Male
;
Middle Aged
;
Prostatectomy/*adverse effects/instrumentation/methods
;
Prostatic Neoplasms/surgery
;
Robotics/instrumentation