Introduction: The Five Medicinal Herb Soak Therapy, as described in the 23rd chapter of “The Secret Quintessential Instructions on the Eight Branches of the Ambrosia Essence Tantra,” a key text in traditional medicine, is noted for its therapeutic applications. It is recommended for conditions such as joint stiffness, tumors, acute and chronic wound swelling, sores, abscesses, hunchback, muscle rheumatism, anthrax, scattered heat and wind disorders. The Five Medicinal Herb Soak consists of Ledum palustre L., Juniperus pseudosabia Fisch.Et M., Myricaria alopecuroides Schrenk., Ephedra Przewalskii Stapf., and Artemisia frigida Willd. This therapy is widely practiced in Mongolia, China, the Inner Mongolia Autonomous Region, the Tibetan Autonomous Region, the Qinghai Province, and the Gansu Province. This clinical observational study review aims to predict treatment outcomes, establish treatment guidelines, and facilitate the development of other pharmaceutical forms. It is anticipated that this review will serve as a scientific reference for the application of the Five Medicinal Herb Soak Therapy. Objective: The objective of this review is to analyze and synthesize clinical studies on the Five Medicinal Herb Soak Therapy. Methods: Keywords “五味甘露” (Wu wei gan lu), “Tibetan medicine five-flavor Manna” were used to search for relevant research articles and theses in biomedical databases, including PubMed (https://pubmed.ncbi. nlm.nih.gov/) and the China National Knowledge Infrastructure CNKI (https://www.cnki.net/). The collected data were systematically analyzed and reviewed. Conclusion The Five Medicinal Herb Soak Therapy demonstrates significant therapeutic value in treating conditions such as gout, rheumatic joint inflammations, digestive disorders, female reproductive system diseases, spinal herniation, arthritis, varicose veins, and scurvy. Integrating this therapy with Mongolian, Tibetan, Chinese, and European medical practices can enhance treatment efficacy by reducing treatment duration, alleviating symptoms, and preventing recurrence. Furthermore, developing more efficient pharmaceutical forms of the Five Medicinal Herb Soak could improve its effectiveness and reduce potential side effects.

Sleep fulfills the vital physiological needs of the human body. However, 45 percent of the world’s population suffers from sleep problems.
In this article, Sugmel 3 tan /prescription/ widely used in traditional medicine for insomnia was selected and biologically active compounds and pharmacological activities of the plants included in the prescription were reviewed. Essential oils from fruits of Amomum kravanh Pierre ex Gagnep and Cuminum cyminum L. are considered to relax the body and mind to improve a night of sleep. Pharmacological and clinical studies of piperine isolated from Piper longum L. fruits demonstrated that the compound possessed anti-depression-like activity and cognitive enhancing effect.

Myocardial infarction (Ml) is necrosis and death of heart muscle secondary to ischemia and acute coronary artery thrombosis. Ml, commonly known as a heart attack, happens when the oxygen rich blood flow to a part of the heart muscle is blocked for a prolonged period, causing damage or death to the heart tissue. This blockage is most often caused by a buildup of fat, cholesterol, and other substances, which form a plaque in the coronary arteries. Furthermore, patients with cancer constitute a high-risk population for cardiovascular disease and as of the last 5 years, 50% of patients with cardiovascular disease have been diagnosed with cancer, according to World Health Organization. The provision of complete insight into Ml complications along with designing ajpreventive program against Ml seems necessary. The use of medications has been practiced over the years for the prevention of HF. However, some of these medications produce adverse effects and due to high cost are not easily available to every patient. Over the past decades, there has been a significant rise in the use of herbal supplements based on traditional medicine to prevent, avoid, and/or treat different conditions, including cardiovascular disease; this rise results from a natural source, efficiency with few or no adverse effects and low cost. In vivo models of heart failure (HF) and myocardial infarction (Ml) are essential for understanding the pathophysiology of these conditions and for developing new treatments.
These models typically involve inducing heart failure or myocardial infarction in animals, such as rodents to study disease mechanisms and evaluate potential therapies.
In this review, we discuss the most common preclinical models of Ml currently employed in cardiovascular research. Among them, Ml induced heart failure is a method of ligation of the left anterior descending artery of coronary an experimental animal. Its physiological relevance, cost-effective, uncomplicated, and suitable method for evaluating research results. The rat model of myocardial infarction offers numerous advantages that make it a valuable tool for cardiovascular research.

Aconitum navicular (Brϋhl) Stapf, a Himalayan endemic, is an endangered medicinal herb of the alpine region. A search was made under the Latin Name Aconitum navicular (Brϋhl) Stapf. to summarize the use of phytochemical and biological information on the use of ethnomedicine available for the species. The keyword “Aconitum navicular (brϋhl) Stapf.” was collected and compiled from the rankings of PubMed, Web of Science, Google Scholar and other scientific websites. Phytochemical analysis done so far has led to the isolation of 14 alkaloids, 3 flavonoid glycosides, and 4 phenolglycosides. Most commonly, aqueous extract of this plant has been used against various kinds of fever, bitter tonic and intoxicating liquors. In addition, Aconitum species contain the most diterpenoid alkaloids, and this compound is bioactive and somewhat toxic. Many studies have shown that diterpenoid alkaloids exhibit cytotoxic, antioxidant, antimicrobial, analgesic, and anti-inflammatory biological activities. We hope this information will be useful in future research and development of this valuable medicinal plant.

Background: Diseases of the digestive system are one of the leading causes of global morbidity, and liver disease is the leading cause, accounting for 52.34% of 100,000 population in Asian countries. In Mongolia, cirrhosis accounted for 32.4% of all liver diseases in 2019.
In traditional medical treatment, liver cirrhosis is included in the scope of chronic diseases and compared with liver’s smug po disease for treatment. In this study, we aimed to clarify the mechanism of action of Tumrinn talkh-7, which is widely used in the treatment of liver diseases, especially in the treatment of liver diseases. Materials and methods: In our study, we used the book named “Oral Instruction Tantra” as main reference material and for research methods, we used the checklist method to list relevant information about the pathogenesis of liver smug po and Tumriin Talkh-7 traditional drug from the literature, so as to provide preconditions for further analysis. The pathogenesis of liver smug po and the action mechanism of Tumriin Talkh-7 were analyzed by theoretical analysis methods and the analysis-synthesis method was used to summarize the analysis results. Results: Due to the hot conditions, the blood heat will increase occur. Due to the cold conditions, food absorption is impaired bad blood is formed in the liver. This is how Smug po disease occurs. Tumriin talkh-7 traditional drugs should be analyzed in relation to the transformation of liver smug po disease.
Iron dust is treating heat liver smug po removed.
Calcitu-CaCO3 is clear phlegm heat.
Dracocephallum foetidum Bge. is cures stomach and liver heat.
Inula helenium L. is equable and cures all liver Smug po diseases.
Saussurea lappa L. is sharp, warm nature, regulating wind-blood disorder.
Trogopterus xanthipes mine Edwards is treating old liver disease.
Carthamus tinctorius L. is saffron cures all liver diseases. Conclusions Pathological blood caused by cold and heat factors leads to liver smug po disease. Tumriin Talkh-7 is a cold drug with the effect of treating hot liver smug po disease.