1.Ventilator support in the pretransplant period predisposes early graft failure after deceased donor liver transplantation
Nuri LEE ; Sora CHA ; Jongman KIM ; Yunmi LEE ; Enjin KANG ; Hyun Jung KIM ; Seung Hui HONG ; Jinsoo RHU ; Gyu-Seong CHOI ; Jae-Won JOH
Annals of Surgical Treatment and Research 2023;105(3):141-147
Purpose:
Deceased donor liver transplantation (DDLT) recipients in Korea are generally sicker due to an increasing organ shortage. In the present study, the risk factors for early 30-day liver graft failure after DDLT were identified.
Methods:
From August 2017 to February 2021, 265 adult DDLTs were performed. The characteristics of patients with and without 30-day graft failure were compared.
Results:
Liver graft failure occurred in 11 patients (17.7%) after DDLT. Baseline and perioperative characteristics of donors and recipients were not statistically significantly different between the 2 groups. The cumulative graft and overall survival rates at 6 months were 83.9% and 88.7%, respectively. Multivariate analysis showed ventilator support in the pretransplant period was a predisposing factor for 30-day graft failure after DDLT.
Conclusion
Present study indicates that cautious decision is required when allocating DDLT in critically ill patients on mechanical ventilatory support.
Result Analysis
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