Chronic pancreatitis is a progressive disease without curative treatment. Abdominal pain is the most predominant symptom of chronic pancreatitis that initially brings most of the patients to the physician's attention. Some studies have correlated the course of pain in chronic pancreatitis in comparison with the duration of the disease, progressing exocrine and endocrine pancreatic insufficiency, and morphological changes such as pancreatic calcification and duct abnormalities. Furthermore, the course of pain has been studied after alcohol abstinence or surgery in some groups. However, there are only few well-performed and valid studies, and some of them even have produced diversing results, in part. Further controlled studies harvoring a large number of patients in a multicenter setting should be considered. Therapeutic efforts on chronic pancreatitis have focused on palliative treatment of pain which is present in about 80% of cases. Endoscopic treatment of pain in chronic pancreatitis is useful and feasible in many patients. Selecting candidate for endotherapy is mandatory. Main indication of pancreatic stent insertion in chronic pancreatitis is the presence of an obvious ductal stricture. Complications of chronic pancreatitis are also indications of endoscopic intervention. Exocrine and endocrine insufficiencies should be meticulously managed to prevent complications and to maintain good quality of life.
English Abstract ; Humans ; Pancreatitis, Chronic/*diagnosis/*therapy

Medical management of acute pancreatitis relies on supportive care such as fluid resuscitation and pain control. Prophylactic antibiotics can reduce the opportunity of infection in severe pancreatitis. The effect of somatostatin or protease inhibitors still needs to be evaluated through further study. Early endoscopic retrograde cholangiopancreatography (ERCP) can ameliorate the course of severe biliary pancreatitis. Although sterile pancreatic necrosis, acute fluid collection, and pseudocyst usually resolve spontaneously, endoscopic or percutaneous drainages are needed when these complications are infected.
Acute Disease ; English Abstract ; Humans ; Pancreatitis/complications/*therapy

Acute pancreatitis is an inflammatory disease of pancreas which come from various etiologies. The pathologic spectrum of acute pancreatitis varies from mild edematous pancreatitis to severe necrotizing pancreatitis. To diagnose and to predict severity in acute pancreatitis, various biochemical marker, imaging modalities and clinical scoring sytstem are needed. Ideal parameters should be accurate, be performed easily and enable earlier assess. Unfortunately, no ideal parameter is available up to date. Serum amylase and lipase are still useful for the diagnosis but meaningless in predicting severity. C-reactive protein and inflammatory cytokines are promising single parameters to predict the severity. CT finding is also an useful determinant of severity, but is expensive and is delayed in assessment.
Acute Disease ; English Abstract ; Humans ; Pancreatitis/*diagnosis ; Severity of Illness Index

From a review on the reality of Dong-In Hospital which was a hospital founded by Dong-Aa Dong-In-Hywe Foundation which was a corporation of governmental patron around Ulsa(1905) protective treaty between Japan and Korea, and this hospital seemed to be dissoluted just before the annexation signing of Korea to Japan. The building with site of Dong-In Hospital in Taegu was sold to Kyung-Sang Pook-Do province and Jaa-Hye Hospital was constructed instead as a virtual conscience. So it is impossible to say this Jaa-Hye Hospital as the predecessor of Dong-In Hospital although Jaa-Hye Hospital which was belonging to Kyung-Sang Pook-Do province as Kyung-Sang Pook-Do Hospital had changed the name several times until being Taegu Medical School Hospital by using as Taegu Medical Institute College Hospital which was absorbed to U.S. military government after the restoration of independence from Japan. Since 1953 Kyungpook National University absorbed Taegu Medical School, it is possible to use Taegu Medical School Hospital as the predecessor of Kyungpook National University Hospital whereas it is impossible to use Jaa-Hye Hospital as the predecessor with nationality on the basis of the health and medical administrative system.
English Abstract ; History of Medicine, 20th Cent. ; Hospitals/*history ; Korea ; *Politics

Treatment for patients with esophageal cancer remains unsatisfactory. Although surgery alone or chemoradiotherapy have been generally accepted as reasonable options for patients with locoregional esophageal cancer, 5-year survival rate of either management is about 20%. The limited success of single modality treatment using radiotherapy or surgery has led to the investigation of multimodality therapies, combining chemotherapy, radiotherapy, and surgery. However, the appropriateness of such therapies remains unanswered. A number of prospective randomized trials of trimodality therapy versus surgery alone suggest benefits of combined-modality therapy. Concurrent chemoradiotherapy is an alternative treatment in selected resectable cases to show potential benefits in survival and local control. Patients with complete response following neoadjuvant therapy have consistent, substantial benefits in survival. Pretreatment staging is necessary for standardization of patients undergoing treatment protocols and for outcome evaluation. Biologic markers can be used to predict response to therapy and might allow designation of treatment based on the individual tumor. In the future, clinical trials testing optimal integration of preoperative regimen including new drugs may impact on the prognosis of esophageal cancer.
Combined Modality Therapy ; English Abstract ; Esophageal Neoplasms/*therapy ; Humans

Paul D. Choy was born on February 26th. 1896. He spent his childhood in Japan and America, and he returned to Korea when he turned twenty one years old. He graduated from Severance Union Medical College in 1921. After graduating the college, he went to Peking Union Medical College to study parasitology. He came back to Korea after one year as the first parasitologist in Korea. On returning, he took the charge of the clinical laboratory of Severance Hospital. Before long he made another journey for study to Canada. He spent two years in Toronto University studying pathology. After studying pathology, he challenged a new field of medicine. It was medical jurisprudence. He stayed two years in Japan in order to earn his doctorate in medical jurisprudence in Tohoku Imperial College. This time he returned as the first specialist in medical jurisprudence in Korea. His field of study was not confined to medical field. He had deep interest in current situation in Manchuria and Mongol, and wrote a book on this matter. His interest also extended to the history of ancient Korean people. He made extensive studies on this subject, which resulted in publishing a huge work on the origin of Korean people and its ancient history. He was a true pioneer of medicine in Korea and his life was characterized by endless quest for learning.
Education, Medical/*history ; English Abstract ; History, 20th Century ; Travel/*history

The Japanese introduction of dentistry into Korea was for treating the Japanese residing in Korea Noda-Oji was the first Japanese dentist for Japanese people in Korea in 1893. and Narajaki doyoyo, an invited dentist was posted in the Korean headquarter of Japanese army in september, 1905. The imperialist Japan licensed the dental technicians (yipchisa) without limit and controled them generously so they could practice dentistry freely. This measure was contrary to that in Japan. (In Japan no new dental technician was licensed.) Komori, a dental technician opened his laboratory at Chungmuro in 1902. The dental technician had outnumerbered by 1920. In 1907, the first Korean dental technician Sung-Ryong Choi practiced dentistry in Jongno. The imperialist Japan made the regulation for dental technicians to set a limit to the advertisement and medical practice of dental technicians. The first Korean dentist Suk-Tae Ham was registered No. 1 in the dentist license. The Kyungsung dental school was established by Nagira Dasoni for the purpose of educating some korean people that contributed to Japanese colonization. It made progress with the help of Japan. it was given the approval of the establishment of the professional school in January the 25th, 1929. it was intended to produce Korean dentists in the first place but became the school for Japanese students later on. The association of Chosun dentist, which had been founded by Narajaki doyoyo, was managed by Japanese dentists in favor of the colonial ruling. The Hansung Association of Dentists established in 1925 was the organization made by the necessity of the association for Koreans only. the Japanese forcefully annexed the Association of Hansung Dentists (Koreans only) to the Association of Kyungsung Dentists to avoid collective actions of Korean dentists in the name of 'Naesunilche'--'Japan and Korea are one'. Their invading intention was shown in the event of 'decayed tooth preventive day'. Japanese controled the gold for dental treatment by licensing and limited the stuff for dental treatment by rationing. The association of Chosun dentists was a group organized for the academic purpose by Nagira Dasoni and etc. In October of 1919, where as the association of kyungsung dentists was constructed on the background of Nagira Dasoni. This establishment of the association of Kyungsung dentists represented a backlash against Ikuda singho having a complete control over the association of Chosun dentists. The number of Koreans who wrote to the Chosun Dental Science Academy was 27, and they wrote 75 articles, which amounted to 15% of 486 articles. The number of Koreans who wrote to the Kyungsung Dental Science Academy was 16, and they wrote 52 articles, which amounted to 11% of 481 articles. These had been a lot of improvement by activity backlash of the dental association. However, they experimented Korean people. The experiments included the experimental stimulation of dental pain by Nagira Dasoni, use of toxic agents on human bodies such as mercury, bismuth and carcinogenic benzole, and experimental treatments with a poor prognosis. Worst of all, the rapid discrimination was stressed. The different dentition according to races was the subject of comparison researches. The dangerous chemicals were sometimes used. The non-akaloid medication was investigated to relieve the dental pain but, the habitual side effects were not unusual by the overuse of morphine or heroin, which was known to be irrelevant due to their habitual side effect. The use of new and unproven material was recommended as well. Especially, the alloy that substituted gold, attracting attention, was substantiated by researches.
Colonialism/*history ; *Dentistry ; English Abstract ; History, 20th Century ; Japan ; Korea

The Research Department of the Severance Union Medical College was founded on November 4th, 1914. Drs. R. G. Mills, J. D. VanBuskirk and A. I. Ludlow were the co-founders of the department. The department aimed at investigating the medical problems of Koreans which originated from the differences of diet, customs and habits. The main fields of the research were divided into three: traditional medicine, diet of the Koreans, and special diseases in Korea. As to the research of the traditional medicine, Mills conducted extensive investigations on the drugs mentioned in the pharmacopeia of the traditional medical texts. His work included the translation of the medical texts into English, which unfortunately was not published, and the collection of thousands traditional drugs and botanical specimens. To the second field, VanBuskirk contributed much. His research was mainly focused on investigating the characteristics of Korean diet, finding out its problems, and recommending more balanced diet. The third field was the research of the diseases specific in Korea. The diseases caused by various parasites were the main targets of the research. At first, the Research Department was a laboratory where research was actually being carried out. But, its nature has been changed as each department became the center of research activities. The Research Department became a research promoting center which provides research funds for each department or individual researchers. The founding of the Research Department in the Severance Union Medical College marks a turning point in the history of SUMC in the sense that academic activities began to become more important in the missionary institute.
English Abstract ; History, 20th Century ; Korea ; Research ; Schools, Medical/*history

Medical education in North Korea began with 2 medical colleges established during the 1930s and 1940s, and each Province came to have one medical college by the 1970s. It is presumed to exist 14 medical colleges in 1992. Apart from medical colleges, there are several kinds of medical schools. the number of medical practitioners has increased as the number of educational institutes for medicine increased. In 1996, there was 29.7 medical practitioners for 10,000 persons. They have several kinds of academic degrees in North Korea. They include: Wonsa, candidate Wonsa, doctor, vice-doctor, candidate doctor. In the university they have professor, associate professor, associate professor, lecturer, and research assistant. Academic degrees and positions are given not by the university nor research institute, but by the Government Board for Awarding Academic Degree and Position. Concerning research institutes, there is Chosen Institute for Medical Science that once was a medical research center under the Central Science Academy, and became an independent institute in 1963. Besides this institute, universities have their own research institutes, and there are also some other independent institutes.
Education, Medical/*history ; English Abstract ; History of Medicine, 20th Cent. ; Korea

Kim Doo-jong, the founder of the history of medicine in Korea, was born on 2nd March, 1896. After finishing his primary education in his home town, he went to Seoul to receive a higher education. He entered Keijo Medical College in 1918. However, at the end of his first year, he participated in the 3 . 1 movement which protested against Japanese harsh rule over Korea. On account of his participation in the movement, he was forced to leave the college which was run by the Japanese colonial government. Then he went to Japan to enter Kyoto Municipal Medical College, from which college he graduated in 1924. After the graduation, he went to Beijing to work in a hospital run by Japanese. Having felt uncomfortable about the situation in Beijing, he moved to Manchuria, where he opened his private clinic and saw patients for 7 years. As the life as a clinician did not satisfy him, he gave up his practice, and determined to devote himself to the study of history of medicine. He was 43 years old when he started studying history of medicine at the Dong Ah Institute, an affiliated research institute of Manchuria Medical College founded by Japanese. The institute had a large and magnificent collection of ancient texts of oriental medicine. He set on historical studies on the oriental medicine from the perspective of the Western medicine. His doctorial dissertation was about anatomy in oriental medicine. He intended to continue his study on organology, myology, etc., but the sudden end of the World War II made him return to Korea. This meant that he could not make access to the large collection of the institute, and his themes of the research had to be changed. On returning to Korea, he established the Department of the History of Medicine in Seoul National University, which was the only and the first one of its kind. He wrote History of Korean Medicine, which still remains one of the most important works on the history of Korean medicine. He was very energetic and active in his academic activities even during his late years. He passed away on 18th May 1988 at the age of 92.
English Abstract ; *Historiography ; History of Medicine, 20th Cent. ; Japan ; Korea