5.Pulmonary Metastases of Uterine Endometrial Stromal Sarcoma: Diffuse Micronodular and Ground Glass Opacities: A Case Report.
Gou Young KIM ; Chang Ohk SUNG ; Joungho HAN ; Joon Oh PARK ; Kyung Soo LEE
Journal of Korean Medical Science 2004;19(6):901-903
Pulmonary metastases of uterine endometrial stromal sarcoma (ESS) are un com-mon. The patterns of uterine ESS metastasis to the lung are multiple pulmonary nodules, single nodule, or cystic lesions. Pulmonary intraalveolar micronodular metastases of uterine ESS are unusual and have not been reported. We experienced a case of metastatic uterine ESS presenting as pulmonary diffuse micronodules with ground glass opacities on chest computed tomography of a 37-yr-old woman who previously underwent hysterectomy due to low grade ESS of the uterus four years ago. The histologic findings of video assisted thoracotomy biopsy showed numerous intraalveolar polypoid micronodules protruding from the alveolar septums. All tumor nodules were composed of short spindle cells arranged in ill-defined whorls, and nuclear feature and sparse cytoplasm were seen in uterine ESS. Immunohistochemically, these cells showed strong nuclear staining for estrogen receptor and progesterone receptor, and diffuse cytoplasmic staining for CD10.
Adult
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Endometrial Neoplasms/*pathology/radiography
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Female
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Humans
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Lung Neoplasms/*pathology/radiography/*secondary
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Sarcoma, Endometrial Stromal/*pathology/radiography/*secondary
6.Uterine endometrial stromal sarcoma with rhabdoid and smooth muscle differentiation.
Yu Hoon KIM ; Hyuni CHO ; Kyeom KIM ; Insun KIM
Journal of Korean Medical Science 1996;11(1):88-93
Uterine and extrauterine tumors composed of cells featuring endometrial stromal cells often show ovarian sex cord-like structures and smooth muscle differentiation. A few cases of endometrial stromal tumors showing rhabdoid differentiation have been reported. The present case is a 20-year-old woman with endometrial stromal sarcoma that had sex cord-like structures, smooth muscle components and rhabdoid differentiation.
Adult
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Case Report
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Cell Differentiation
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Endometrial Neoplasms/*pathology
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Female
;
Human
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Muscle, Smooth/*pathology
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Rhabdoid Tumor/*pathology
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Sarcoma, Endometrial Stromal/*pathology
10.Lymph Node Metastasis in a Gynecologic Malignancy.
Toshiharu KAMURA ; Jin Dong JEON
Yonsei Medical Journal 2002;43(6):783-791
A radical hysterectomy was performed on patients with stage IA2 to IIB cervical cancer. For these patients, many histopathological parameters have been reported to be prognostic factors of cervical cancer, such as a pelvic lymph node (PLN) metastasis, the histological subtype, the tumor diameter, the depth of the stromal invasion, a lymph-vascular space invasion (LVSI), a parametrial invasion, a corpus invasion and a vaginal invasion. Ovarian cancer is normally treated with cytoreductive surgery followed by chemotherapy. Although physicians have paid a great deal of attention to intraperitoneal disease, a substantial number of ovarian cancers have reported to involve the retroperitoneal lymph nodes. Therefore, a lymph node metastasis has been introduced into FIGO staging. However, the prognostic significance of a lymph node metastasis is controversial. In order to determine the possibility of individualizing a pelvic lymph node (PLN) dissection in patients with endometrial cancer, the relationship between PLN metastasis and the various prognostic factors was investigated. In this paper, various prognostic variables including a lymph node metastasis were analyzed in cervical cancer, enodometrial cancer, and ovarian cancer.
Cervix Neoplasms/pathology
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Endometrial Neoplasms/pathology
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Female
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Genital Neoplasms, Female/*pathology
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Human
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Lymphatic Metastasis
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Ovarian Neoplasms/pathology