No abstract available.
Endolymphatic Hydrops*

Meningioma's account for around 15% of all primary brain tumors with some 10% of meningiomas arising in the posterior fossa. In rare cases, a meningioma can form around the endolymphatic sac. When formed in the posterior fossa, meningioma tumors can produce vague, non-specific vertiginous symptoms. Research has observed that a subset of these lesions could produce symptoms indistinguishable from those of Meniere's disease. Therefore, we described the clinical features of a case of posterior petrous meningioma with recurrent vertigo as well as the substantial resolution of symptoms after tumor removal via transmastoid approach.
Brain Neoplasms ; Endolymphatic Hydrops ; Endolymphatic Sac ; Meniere Disease ; Meningioma ; Vertigo

Author divided the history of Meniere's disease into a three part based on two important historical affairs, the novel concept of Prosper Meniere which reported in 1861, and the discovery of temporal bone histopathology of endolymphatic hydrops by Hallpike and Yamakawa in 1938. This article traces the period since Prosper Meniere's report until discovery of endolymphatic hydrops.
Endolymphatic Hydrops* ; History of Medicine ; Meniere Disease* ; Temporal Bone

BACKGROUND AND OBJECTIVES:Electrocochleography is the only proven investigation and diagnostic tool to demonstrate the endolymphatic hydrops at this time. We designed this study to assess the characteristics of transtympanic electrocochleographic findings and to estimate the clinical value of the test results in the patients with Meniere's disease. MATERIALS AND METHOD:Electrocochleographic duration and amplitude were measured in a clinically defined definite Meniere's disease group and the results were compared with those from a normal hearing control group. RESULTS:The summating potential (SP)/action potential (AP) amplitude ratio was significantly different among study groups with 0.40+/-.10 in the bilateral Meniere's group, 0.34+/-.08 in the unilateral Meneire's group and 0.22+/-.08 in the normal group (p<0.01). The elevated SP/AP ratio in the patients with such a relatively long duration of Meniere's disease in this study was mainly due to the decreased AP amplitude rather than the enhanced SP amplitude. CONCLUSION:Measuring electrocochleography and demonstrating the elevated SP/AP ratio could be quite valuable to diagnose the patients with Meniere's disease. The recognition of decreased AP amplitude might be helpful to understand the cochlear pathologic status in the patients with Meniere's disease.
Audiometry, Evoked Response* ; Endolymphatic Hydrops ; Hearing ; Humans ; Meniere Disease*

The etiology and pathophysiology of Meniere's disease (MD) remain controversial and incompletely understood. Diagnosis of MD is decided according to the diagnostic criteria proposed by the American Academy of Otolaryngology-Head and Neck Surgery (AAO) (1995), which is based on clinical symptoms. It would be of great value to have an objective clinical test for the diagnosis of endolymphatic hydrops. Various tests like electrocochleography, vestibular evoke myogenic potential and cochlear hydrops analysis masking procedures have been applied for detecting endolymphatic hydrops. Any of single objective tests is not perfect for the diagnosis of MD. However, considering AAO guideline is not enough for the diagnosis, additive objective tests for MD become essential. We evaluated the objective tests for MD and also surveyed preferred tests among Korean otologic society members.
Audiometry, Evoked Response ; Edema ; Endolymphatic Hydrops ; Masks ; Meniere Disease ; Neck

No abstract available.
Dehydration ; Endolymphatic Hydrops

There are only a few reports of post-traumatic Meniere's disease and there is few literature that contains detailed data associated with the disease. We report a case of post-traumatic Meniere's disease. He suffered from tinnitus, fluctuating sensorineural hearing loss, and recurrent vertigo. Symptomatic medical treatment was not helpful and neither was soft tissue plugging around the oval and round windows during exploratory tympanotomy. Three months after soft tissue plugging, endolymphatic sac decompression surgery was performed. The patient's symptoms improved markedly thereafter. The clinical significance of post-traumatic Meniere's disease is described and we present a brief review of the literature.
Decompression ; Endolymphatic Hydrops ; Endolymphatic Sac ; Hearing Loss, Sensorineural ; Meniere Disease* ; Tinnitus ; Vertigo

Endolymphatic hydrops is a representing pathologic finding of Ménière's disease. For the induction of endolymphatic hydrops in an animal model, surgical ablation of endolymphatic sac has been used. Although traditional model with the blockage of endolymphatic sac induced severe hydrops, it has several limitations for the study of pathophysiology of Ménière's disease. Recently, modified experimental models have been introduced, in which additional procedure was performed to induce the acute aggravation of hydrops after the surgical ablation. These new models could be helpful to elucidate the mechanism and develop a new treatment of Ménière's disease. In this review, we introduce the characteristics of animal models using surgical ablation of endolymphatic sac from the classical model to novel modified models.
Edema ; Endolymphatic Hydrops ; Endolymphatic Sac ; Meniere Disease ; Models, Animal ; Models, Theoretical

Posterior fossa meningioma located on the endolymphatic sac may present Meniere's disease-like symptoms possibly due to endolymphatic hydrops by tumor compression. A 70-year-old woman presented with recurrent vertigo and combined hearing loss that had lasted for 6 years. She had been diagnosed as left-sided posterior fossa meningioma with a maximum diameter of 20.3x7.7x12 mm about 10 years ago and had been followed up regularly. Since then she was found with a slightly increased tumor and thus referred to our department for the treatment of intractable recurrent vertigo accompanying Tumarkin attacks with secondary head trauma. Since pharmaceutical treatment was not effective, intratympanic gentamicin was repeatedly injected. After successful ablation of vestibular function, no further recurrence of vertigo or Tumarkin attack was reported. This case illustrates that posterior fossa meningioma can be intimately involved with endolymphatic sac and present symptoms and signs suggestive of endolymphatic hydrops.
Aged ; Craniocerebral Trauma ; Endolymphatic Hydrops ; Endolymphatic Sac ; Female ; Gentamicins ; Hearing Loss ; Humans ; Meniere Disease ; Meningioma ; Recurrence ; Vertigo

Endolymphatic hydrops is believed to be underlying pathophysiology of Meniere's disease. The degree of endolymphatic hydrops observed by MRI (magnetic resonance imaging) in patients with Meniere's disease offers a new method to study the progression of Meniere's disease. There have been multiple attempts to diagnose Meniere's disease with the help of radiologic tests including MRI in Korea. We describe a case report of a patient with Meniere's who showed changes of endolymphatic sac in MRI after endolymphatic sac decompression.
Decompression ; Endolymphatic Hydrops ; Endolymphatic Sac ; Humans ; Korea ; Magnetic Resonance Imaging ; Magnetic Resonance Spectroscopy ; Magnetics ; Magnets ; Meniere Disease