1.Intracranial Endodermal Sinus Tumor:Review of Literature.
Linda Eunshin HAAH ; Jung Keun SUH ; Hoon Kap LEE ; Jeong Wha CHU ; Ki Chan LEE
Journal of Korean Neurosurgical Society 1992;21(2):201-213
No abstract available.
Endoderm*
2.Treatment of Vaginal Endodermal Sinus Tumor.
Seok Joo HAN ; Myo Kyung LEE ; Chuhl Joo LYU ; Byung Soo KIM ; Eui Ho HWANG
Journal of the Korean Pediatric Society 1995;38(5):707-712
No abstract available.
Endoderm*
;
Endodermal Sinus Tumor*
3.Clinical survey of 8 cases of endodermal sinus tumor.
Kwang Soon AHN ; Rae Ok PARK ; Jung Il CHA ; Byung Hun JUNG ; Jin Woo KIM ; Se Il KIM ; Sung Eun NAMKOONG ; Seung Jo KIM
Korean Journal of Obstetrics and Gynecology 1992;35(1):68-76
No abstract available.
Endoderm*
;
Endodermal Sinus Tumor*
4.Primary Endodermal Sinus Tumor In The Sacrococcygium.
Jong In KIM ; Jin YANG ; Ik Jun LEE ; Young Hyun KWAK
Journal of the Korean Pediatric Society 1983;26(6):584-588
No abstract available.
Endoderm*
;
Endodermal Sinus Tumor*
5.Treatment of endodermal sinus tumor with cisplatin/etoposide/bleomycin.
Journal of the Korean Cancer Association 1993;25(2):261-267
No abstract available.
Endoderm*
;
Endodermal Sinus Tumor*
6.A case of endodermal sinus tumor of the ovary treating with BEP regimen.
Mi Young KIM ; Chu Yeop HUR ; Seong Bo KIM
Korean Journal of Obstetrics and Gynecology 1993;36(8):3358-3365
No abstract available.
Endoderm*
;
Endodermal Sinus Tumor*
;
Female
;
Ovary*
7.Mesenchymal Stem Cells: The Promotion of Endodermal-Induction Using Activin A.
Sang Woo LEE ; Seon Ok MIN ; Shin Young KIM ; Sae Byeol CHOI ; Hyun Ok KIM ; Kyung Sik KIM
Korean Journal of Hepato-Biliary-Pancreatic Surgery 2009;13(4):205-214
PURPOSE: The most important consideration for therapy using MSCs is the differentiation of the target organ's cell type. For in-vitro hepatogenic differentiation of MSCs, the main focus is efficient induction of the MSCs into the endoderm stage. Activin A, which is a signaling molecule that is similar to Nodal, promotes the induction of definitive endoderm from both ESs and MSCs. The protocols for induction into definitive endoderm have shown different efficiency and reproducibility depending on the researchers or the sources of the MSCs. Thus, a study on the various conditions of Activin A is needed to efficiently differentiate MSCs into the definitive endoderm lineage of MSCs. METHODS: MSCs were isolated from human adipose tissues and these were cultured in MCM (MSCs Culture Medium) on a human fibronectin coated plate. At 70~80% confluence, the MSCs were harvested and cultured in MCM supplemented with Activin A, at a 50 ng/mL concentration, and FGF4. The expression of the genes related with MSCs or primitive endoderm were analyzed by RT-PCR. The changes of cell morphology for differentiation were also observed by a light microscope & a SEM. RESULTS: The expression of genes related with primitive foregut endoderm was seen in the groups that were treated with a higher concentration of Activin A. The morphology of the cells that differentiated into definitive endoderm were not different from those of the undifferentiated MSCs. The expression of genes related with functional primitive hepatocytes was seen in the early phase during hepatic differentiation. The cell morphology was changed to a similar cuboidal form in a time-dependent manner. CONCLUSION: Activin A promotes a more rapid induction of definitive endoderm. It also makes an efficient condition for the differentiation into primitive foregut endoderm at a higher concentration.
Activins
;
Endoderm
;
Fibronectins
;
Hepatocytes
;
Humans
;
Light
8.Mesenchymal Stem Cells: The Promotion of Endodermal-Induction Using Activin A.
Sang Woo LEE ; Seon Ok MIN ; Shin Young KIM ; Sae Byeol CHOI ; Hyun Ok KIM ; Kyung Sik KIM
Korean Journal of Hepato-Biliary-Pancreatic Surgery 2009;13(4):205-214
PURPOSE: The most important consideration for therapy using MSCs is the differentiation of the target organ's cell type. For in-vitro hepatogenic differentiation of MSCs, the main focus is efficient induction of the MSCs into the endoderm stage. Activin A, which is a signaling molecule that is similar to Nodal, promotes the induction of definitive endoderm from both ESs and MSCs. The protocols for induction into definitive endoderm have shown different efficiency and reproducibility depending on the researchers or the sources of the MSCs. Thus, a study on the various conditions of Activin A is needed to efficiently differentiate MSCs into the definitive endoderm lineage of MSCs. METHODS: MSCs were isolated from human adipose tissues and these were cultured in MCM (MSCs Culture Medium) on a human fibronectin coated plate. At 70~80% confluence, the MSCs were harvested and cultured in MCM supplemented with Activin A, at a 50 ng/mL concentration, and FGF4. The expression of the genes related with MSCs or primitive endoderm were analyzed by RT-PCR. The changes of cell morphology for differentiation were also observed by a light microscope & a SEM. RESULTS: The expression of genes related with primitive foregut endoderm was seen in the groups that were treated with a higher concentration of Activin A. The morphology of the cells that differentiated into definitive endoderm were not different from those of the undifferentiated MSCs. The expression of genes related with functional primitive hepatocytes was seen in the early phase during hepatic differentiation. The cell morphology was changed to a similar cuboidal form in a time-dependent manner. CONCLUSION: Activin A promotes a more rapid induction of definitive endoderm. It also makes an efficient condition for the differentiation into primitive foregut endoderm at a higher concentration.
Activins
;
Endoderm
;
Fibronectins
;
Hepatocytes
;
Humans
;
Light
9.Endodermal Sinus Tumor in Children.
Jae Sun JUNG ; Hyo Seop AHN ; Chang Yee HONG
Journal of the Korean Pediatric Society 1988;31(6):772-778
No abstract available.
Child*
;
Endoderm*
;
Endodermal Sinus Tumor*
;
Humans
10.A Case of Retroperitoneal Teratoma.
Young Hwa YOON ; Chang Su JUNG ; Shin JUNG ; Soon Chang KIM ; Sam Keuk NAM ; Hyo Jin LEE
Korean Journal of Urology 1998;39(10):1040-1042
Retroperitoneal teratoma is a rare tumor composed of tissues from all three germ cell layers - endoderm, mesoderm, ectoderm. It is generally known as a disease of baby or children and as 10% of retroperitoneal tumor. Recently, we experienced a case of retroperitoneal teratoma in adult.
Adult
;
Child
;
Ectoderm
;
Endoderm
;
Germ Cells
;
Humans
;
Mesoderm
;
Teratoma*