Humans ; Endocarditis, Bacterial/surgery* ; Arthritis/etiology* ; Endocarditis/surgery*

Aneurysm, Infected/surgery* ; Endocarditis/surgery* ; Endocarditis, Bacterial/surgery* ; Humans ; Intracranial Aneurysm/surgery*

Aged ; Aortic Valve ; pathology ; surgery ; Endocarditis ; complications ; surgery ; Endocarditis, Bacterial ; complications ; surgery ; Female ; Glomerulonephritis ; etiology ; Humans

Adult ; Endocarditis/surgery* ; Endocarditis, Bacterial/surgery* ; Hospital Mortality ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Risk Factors ; Young Adult

The epidemiology of Group B streptococcal disease has been changing. Since the 1990s, early-onset neonatal and maternal peripartum infections have decreased, due to the administration of prophylactic intrapartum antibiotics. On the other hand, invasive Group B streptococcal infections have increased in nonpregnant adults, especially in elderly persons and in those with chronic immunosuppressive diseases, such as diabetes mellitus, liver cirrhosis, and malignancies. Although infective endocarditis is an uncommon manifestation of invasive Streptococcus agalactiae infection, it usually leads to cardiac surgery, due to heart failure associated with rapid valve destruction and the formation of emboli. Several cases of endocarditis due to S. agalactiae have appeared in the literature, but there have been few reports in Korea. We present a case of S. agalactiae infective endocarditis in an elderly patient with advanced gastric cancer, successfully treated with intravenous antibiotics and cardiac surgery.
Adult ; Aged ; Anti-Bacterial Agents ; Diabetes Mellitus ; Endocarditis ; Endocarditis, Bacterial ; Hand ; Heart Failure ; Humans ; Korea ; Liver Cirrhosis ; Peripartum Period ; Stomach Neoplasms ; Streptococcal Infections ; Streptococcus ; Streptococcus agalactiae ; Thoracic Surgery

The epidemiology of Group B streptococcal disease has been changing. Since the 1990s, early-onset neonatal and maternal peripartum infections have decreased, due to the administration of prophylactic intrapartum antibiotics. On the other hand, invasive Group B streptococcal infections have increased in nonpregnant adults, especially in elderly persons and in those with chronic immunosuppressive diseases, such as diabetes mellitus, liver cirrhosis, and malignancies. Although infective endocarditis is an uncommon manifestation of invasive Streptococcus agalactiae infection, it usually leads to cardiac surgery, due to heart failure associated with rapid valve destruction and the formation of emboli. Several cases of endocarditis due to S. agalactiae have appeared in the literature, but there have been few reports in Korea. We present a case of S. agalactiae infective endocarditis in an elderly patient with advanced gastric cancer, successfully treated with intravenous antibiotics and cardiac surgery.
Adult ; Aged ; Anti-Bacterial Agents ; Diabetes Mellitus ; Endocarditis ; Endocarditis, Bacterial ; Hand ; Heart Failure ; Humans ; Korea ; Liver Cirrhosis ; Peripartum Period ; Stomach Neoplasms ; Streptococcal Infections ; Streptococcus ; Streptococcus agalactiae ; Thoracic Surgery

American Heart Association ; Anti-Bacterial Agents ; administration & dosage ; therapeutic use ; Cardiac Surgical Procedures ; Child ; Drug Resistance, Bacterial ; Drug Therapy, Combination ; Endocarditis ; drug therapy ; surgery ; Endocarditis, Bacterial ; drug therapy ; surgery ; Humans ; Practice Guidelines as Topic ; United States

Endocarditis related to pacemaker-lead infection is a rare complication characterized by infection on the pacemaker electrode tip, tricuspid valve, or the fibrotic endocardial areas that are in contact with the electrode tip. However, it is a serious, potentially life-threatening complication. We experienced a case of pacemaker endocarditis in a 39-year old male patient in whom a permanent pacemaker had been inserted four years before. The diagnosis was made by the demonstration of vegetations on the electrode tip of the pacemaker, that was detected by transthoracic echocardiography and isolation of methicillin-resistant Staphylococcus epidermidis from blood culture. The patient was managed with antibiotics for six weeks and the infected electrode was removed by open heart surgery.
Adult ; Anti-Bacterial Agents ; Diagnosis ; Echocardiography ; Electrodes ; Endocarditis* ; Humans ; Male ; Methicillin Resistance ; Staphylococcus epidermidis ; Thoracic Surgery ; Tricuspid Valve

Endocarditis related to pacemaker-lead infection is a rare complication characterized by infection on the pacemaker electrode tip, tricuspid valve, or the fibrotic endocardial areas that are in contact with the electrode tip. However, it is a serious, potentially life-threatening complication. We experienced a case of pacemaker endocarditis in a 39-year old male patient in whom a permanent pacemaker had been inserted four years before. The diagnosis was made by the demonstration of vegetations on the electrode tip of the pacemaker, that was detected by transthoracic echocardiography and isolation of methicillin-resistant Staphylococcus epidermidis from blood culture. The patient was managed with antibiotics for six weeks and the infected electrode was removed by open heart surgery.
Adult ; Anti-Bacterial Agents ; Diagnosis ; Echocardiography ; Electrodes ; Endocarditis* ; Humans ; Male ; Methicillin Resistance ; Staphylococcus epidermidis ; Thoracic Surgery ; Tricuspid Valve

Fungal prosthetic valve endocarditis is a rare, poo-prognostic disease. The risk factors for fungal valve endocardits are open heart surgery, hyperalimentation, antibiotic therapy, IV drug abuse, concomitant bacterial endocarditis and immunosuppression. We report a case of aspergillus endocarditis in the aortic valve, which extended to ascending aorta after Redo-aortic valve replacement surgery. A 22-year-old male patient underwent Redo-aortic valve replacement surgery with 23mm-sized Sorin valve(bi-leaflet tilting disc valve) due to prosthetic valve failure. He was readmitted because of development of cough, anorexia, fatigue and fever after operation. The results of repeated blood culture were negative, and the symptoms continued in spite of 2 week treatment with broad spectrum antibiotics. Echocardiography and spiral computed tomographic angiography revealed multiple, huge masses in the aortic valve extending to ascending aorta. Emergent surgery was performed. Infected valve and surrounding areas were widely excised and aortic homograft was inserted. Resected aorta and prosthetic valve showed multiple mass-forming vegetations, measuring up to 4cmx3cmx3cm. Microscopically, they revealed fungal organisms, showing sharp-angle branching and septate hyphae. Aspergillus flavus was isolated in culture of resected tissue. The patient suddenly died of ventricular fibrillation 3 weeks after surgery in spite of treatement with intravenous amphotericin B.
Allografts ; Amphotericin B ; Angiography ; Anorexia ; Anti-Bacterial Agents ; Aorta ; Aortic Valve ; Aspergillus ; Aspergillus flavus ; Cough ; Echocardiography ; Endocarditis* ; Endocarditis, Bacterial ; Fatigue ; Fever ; Humans ; Hyphae ; Immunosuppression ; Male ; Risk Factors ; Substance-Related Disorders ; Thoracic Surgery ; Ventricular Fibrillation ; Young Adult