Objective To evaluate the nutritional status and nursing nutritional guidance in maintenance of hemodialysis patients(MHD).Methods 48 cases of MHD were selected and randomly divided into two groups:experimental group(n=23)and control group(n=25).Control group was siven routine nursing.Experimental group waft given routine nursing plus nutritional guidance.Results After six months nutritional guidance,the nutritional status of the experimental group are better significantly than that of the control group(P<0.05).Conclusions Nutritional guidance Call significantly improve the nutritional status of the MHD.