ObjectiveTo study the preventive and therapeutic effects of Baxianxiaoyao decoction medicated bath on pressure injury wound in rats.Methods The research was started from April 2016 to February 2017. The experiment was approved by the animal experimental ethics committee and was finished in the basic medical laboratory of Nagano University of Nursing in Japan. A total of 24 rats were divided into 3 groups averagely,and there were the control group(group A),the tap-water bath group(group B) and the traditional Chinese medicine bath group(group C). Group B rats used tap-water bath,and group C rats used traditional Chinese medicine bath,while the rats in group A did not bath. After bathing for 2 weeks,the pressure injury model was made on the rats' skin,and then the average of ulcer area and the maximum- minimum concentration difference were calculated by Image-J ;besides the healing rate,wound center temperature,skin moisture were compared among the three groups.Results For the 12 h pressure injury area after three groups rats model established,the group A was(137.060±18.258) mm2,Group B(123.310±14.969) mm2,group C (92.520±11.159) mm2(F=73.235,P<0.05);Image-J measures the average area of pressure injury picture among three groups and maximum-minimum concentration difference of picture(F=8.13,4.91;P<0.01).The rate of wound healing was statistically difference after the PI model at 12 hours,4 days,8 days,12 days (F=8.058, 12.024,17.360,26.006;P<0.05);however,the skin moisture had no statistical significance (P>0.05). Conclusions Baxianxiaoyao Decoction medicated bath is an effective way to prevent and treat pressure injury wound,and it can promote wound healing.

Constraint-induced movement therapy (CIMT) has been a well-established rehabilitative method for upper limb paralysis in patients post-stroke. In recent years, its application to lower limb paralysis (Lower limb CIMT, L-CIMT) has been reported. However, the reported intensive lower limb trainings do not seem enough to target behavioral modifications in an individual's daily life. In this study, we investigated the effects of L-CIMT including the transfer package to induce behavioral transformation in normal daily life of patients with lower limb paralysis. The L-CIMT including the transfer package was administered to three patients with chronic-phase stroke without any constraint on the healthy lower limb for 3.5 hours a day, 5 days a week for 3 weeks. As a result, standing balance and walking ability were improved immediately and within 6 months after the intervention, respectively. All three cases experienced increased daily opportunities for standing and walking. We believe that L-CIMT including the transfer package can bring both short- and long-term improvements in standing balance and walking ability. This can lead to an increase in the frequency of standing and walking in daily living, along with an expanded range of action in ADL and IADL in patients with chronic-phase stroke.

Constraint-induced movement therapy (CIMT) has been a well-established rehabilitative method for upper limb paralysis in patients post-stroke. In recent years, its application to lower limb paralysis (Lower limb CIMT, L-CIMT) has been reported. However, the reported intensive lower limb trainings do not seem enough to target behavioral modifications in an individual's daily life. In this study, we investigated the effects of L-CIMT including the transfer package to induce behavioral transformation in normal daily life of patients with lower limb paralysis. The L-CIMT including the transfer package was administered to three patients with chronic-phase stroke without any constraint on the healthy lower limb for 3.5 hours a day, 5 days a week for 3 weeks. As a result, standing balance and walking ability were improved immediately and within 6 months after the intervention, respectively. All three cases experienced increased daily opportunities for standing and walking. We believe that L-CIMT including the transfer package can bring both short- and long-term improvements in standing balance and walking ability. This can lead to an increase in the frequency of standing and walking in daily living, along with an expanded range of action in ADL and IADL in patients with chronic-phase stroke.