No abstract available.
Body Weight* ; Diet* ; Exercise Therapy* ; Humans

PURPOSE: Although the number of patients with measles have dramatically decreased since the introduction of measles vaccines in 1965, measles outbreaks have occurred periodically every 4-6 years during the 1990s(1989-1990 and 1993-1994). During 2000-2001, measles prevailed all over the country again. A characteristic of current epidemics is that the majority of affected population was infants and school-aged children. This study was designed to analyze the epidemic and clinical features of measles prevalence during 2000-2001 and to find ways to overcome vaccination failure. METHODS: We reviewed the records of 59 patients with mealses admitted in the Pediatric Department of Pusan National University Hospital from January 2000 to October 2001 for patient's age, month of admission, history of vaccination, clinical features and complications. Antibody titers of measles-specific IgM and IgG were measured by enzyme immunoassay. RESULTS: The epidemic show two peaks in the age distribution. Forty three patients(72.9%) were under 2-years of age and 14 patients(23.7%) were over 5-years of age. Outbreaks had high incidence in July to August, 2000 and March to April, 2001, then faded away after July, 2001. Vaccinated group comprised 30.5% and unvaccinated group comprised 69.5% and their mean age was 9.25+/-4.27 years old and 0.95+/-0.30 years old respectively. Positive rate of IgM was 86.7% in vaccinated group and 90.3% in unvaccinated group. This means there was primary vaccine failure; 13 cases of 15 vaccinated patients were positive in IgM antibody. During the prevalence, two patients died with mealses complication. One of them was immunocompromised. CONCLUSION: To prevent another prevalence of measles in the future, we must enhance revaccination at ages 4-6 and check vaccination status when children enter elementary school. These will produce over 95% of herd immunity, with catch-up MMR vaccination which has been completed already.
Age Distribution ; Busan ; Child ; Disease Outbreaks ; Humans ; Immunity, Herd ; Immunization, Secondary ; Immunoenzyme Techniques ; Immunoglobulin G ; Immunoglobulin M ; Incidence ; Infant ; Meals ; Measles* ; Prevalence ; Vaccination ; Vaccines

The coverage of soft tissue defects around the knee joint or upper one third of lower leg presents a difficult challenge to the reconstructive surgeon. Various reconstructive choices are available depending on the location, size and depth of the defect. The authors present their clinical application of a medial sural artery perforator island flap as a useful alternative method for upper one third of lower leg and knee reconstruction. From 2002 to 2004, we operated total 4 patients (total 4 flaps) using the medial sural artey perforator island flap for coverage of the defect on upper one third of lower leg and knee, of 4 patients, 3 patients was men and one was woman. Average patient age was 54.6 years. The largest flap obtained was 10x8cm2. Postoperative follow up of the patients ranged from two to 33 months. In two cases, defects was located on upper one third of lower leg and in other two cases, defects were on the knee. All four cases had bone exposure open wound. In angiography, 2 cases had injured in the anterior tibial artery, 1 case had injured in the posterior tibial artery. There were no diabetes or other vascular disease. All 4 flaps were survived completely, without minor complications such as venous congestion and hematoma. Donor morbidity was restricted substantially to the donor linear scar. There were no functional impairment. As the main advantages of the medial sural perforator island flap, it ensures constant location and reliable blood supply without sacrificing any main source artery or damaging underlying muscle. This procedure is valuable extension of local flap for defect coverage with minimal functional deficit donor site and good aesthetic result on the defect. We consider it as one of the useful methods of the upper one third of lower leg and knee reconstruction.
Angiography ; Arteries ; Cicatrix ; Female ; Follow-Up Studies ; Hematoma ; Humans ; Hyperemia ; Knee Joint ; Knee* ; Leg* ; Lower Extremity ; Male ; Tibial Arteries ; Tissue Donors ; Vascular Diseases ; Wounds and Injuries

Behcet disease is a chronic systemic inflammatory disease involving mucous membranes, skin, eyes, gastrointestinal tract, joints, vessels, and neurologic systems. The disease usually manifests in early adulthood. Childhood onset is rare. We experienced a case of Behcet disease in a 11-year-old boy. He suffered from recurrent arthritis of the left knee joint which was managed under the impression of septic arthritis since he was seven years old. Behcet disease should be considered in case of recurrent arthritis mimicing septic arthritis in children.
Arthritis* ; Arthritis, Infectious ; Behcet Syndrome* ; Child ; Gastrointestinal Tract ; Humans ; Joints ; Knee Joint ; Male ; Mucous Membrane ; Skin

Undifferentiated squamous cell carcinoma, lymphoepithelioma-like carcinoma of salivary glands is rare disease, the incidence of which is highest among the Inunit of Greenland and North America. By the way, the relation of Epstein-Barr virus(EBV) with this tumor has not been studied to any great extent here in Korean because of rare number of cases. Correlations between lymphoepithelioma and EBV have been investigated with morphologic and pathologic evaluation. Recently, nonnasopharyngeal neoplasms, which have morphologic features identical to those lymphoepithelioma, called lymphoepithelioma- like carcinoma(LEC). We experienced the treatment of lymphoepithelioma-like carcinoma arising from the parotid gland and a case is presented with the review of literatures.
Carcinoma, Squamous Cell ; Greenland ; Herpesvirus 4, Human ; Incidence ; North America ; Parotid Gland* ; Rare Diseases ; Salivary Glands

PURPOSE: The purpose of this study is to evaluate the usefulness of the trans-septal approach for treating popliteal cyst, to determine the frequency and types of the associated pathologies and to assess the follow up ultrasound evaluation. MATERIALS AND METHODS: From February, 2002 to February, 2007, 44 patients with popliteal cyst were treated by arthroscopy only. Fourteen patients were male and 30 patients were female. Their average age was 50 years (range: 20~77 years). We used the trans-septal portal approach. We evaluated the satisfaction of the patients and the recurrence of the popliteal cyst by performing ultrasound exams at an average follow up of 36 months after surgery. At the final follow up, we evaluated the clinical results by the criteria of Rauschning and Lindgren. RESULTS: We found no communication between the knee joint and the popliteal cyst by CT or MRI in 4 cases (8%), but we found a communication by arthroscopy in all the cases. Thirty-four cases had intra-articular pathologies and 9 cases didn't. The total intra-articular pathologies included 17 articular cartilage defects or chondral lesion (38%) and 15 meniscus tears (34%). In 1 case, open excision was performed for the revision surgery because the patient had recurrence of the popliteal cyst, which caused compressive neuropathy of the common peroneal and tibial nerve. At the last follow up, the clinical outcome of surgery according to the criteria of Rauschning and Lindgren was grade 0 (28 cases), grade1 (12 cases), grade 2 (3 cases) and grade 3 (1 case). CONCLUSION: We can approach the orifice of a popliteal cyst directly with using the trans-septal portal and easily decompress the orifice of the cyst. We propose that the arthroscopic decompression using the trans-septal portal is an excellent treatment modality for popliteal cysts.
Arthroscopy ; Cartilage, Articular ; Decompression ; Female ; Follow-Up Studies ; Humans ; Knee Joint ; Male ; Popliteal Cyst ; Recurrence ; Tibial Nerve

Compartment syndrome is rarely associated with non-traumatic rhabdomyolysis. We report the case of a 23-year-old man who developed compartment syndrome associated with rhabdomyolysis caused by prolonged immobilization after antidepressive drug overdose. Elevation of serum creatine phosphokinase and myoglobinuria indicated rhabdomyolysis. Painful swelling of the right buttock and thigh and right lower limb paralysis with sensory and motor deficit were suggestive of gluteal and thigh compartment syndrome with the complication of sciatic nerve injury. The patient received an immediate fasciotomy, medical treatment and rehabilitation. At five months after initial treatment, the patient could walk independently with nearly full recovery of his right lower limb function.
Buttocks ; Compartment Syndromes ; Creatine Kinase ; Drug Overdose ; Humans ; Immobilization ; Lower Extremity ; Myoglobinuria ; Paralysis ; Rhabdomyolysis ; Sciatic Nerve ; Thigh ; Young Adult

Oxidative stress plays various roles in the development and progression of IgA nephropathy, while bilirubin is known as a potent antioxidant. We therefore hypothesized that serum bilirubin would be associated with renal prognosis in IgA nephropathy. The study subjects comprised 1,458 adult patients with primary IgA nephropathy in Korea. We grouped patients according to the following quartile levels of bilirubin: <0.4 mg/dL (Q1), 0.4-0.5 mg/dL (Q2), 0.6-0.7 mg/dL (Q3), and >0.8 mg/dL (Q4). The outcome data were obtained from the Korean Registry of end-stage renal disease (ESRD). Eighty patients (5.5%) contracted ESRD during a mean follow-up period of 44.9 months. The ESRD incidences were 10.7% in Q1, 8.2% in Q2, 2.8% in Q3, and 2.8% in Q4 (p<0.001). The relative risk of ESRD compared to that in Q1 was 0.307 (95% confidence interval [CI], 0.126-0.751) in Q3 and 0.315 (95% CI, 0.130-0.765) in Q4. The differences of ESRD incidence were greater in subgroups of males and of patients aged 35 yr or more, with serum albumin 4.0 g/dL or more, with normotension, with eGFR 60 mL/min/1.73 m2 or more, and with proteinuria less then 3+ by dipstick test. In conclusion, higher bilirubin level was negatively associated with ESRD incidence in IgA nephropathy.
Adult ; Bilirubin/*blood ; Disease Progression ; Female ; Glomerular Filtration Rate ; Glomerulonephritis, IGA/*blood/complications ; Humans ; Hypertension/complications ; Incidence ; Kidney Failure, Chronic/*blood/complications ; Male ; Middle Aged ; Risk ; Risk Factors ; Treatment Outcome