Succinylcholine is a depolarizing neuromuscular blocking agent(NMB) and is used in induction of anesthesia. Succinylcholine-assisted endotracheal intubation has been routinely used in the operating room and rapid sequence incubation with NMB agent has been the method for airway management in emergency department(ED). Adverse effects of succinylcholine are hyperkalemia, malignant hyperthermia, transient hypotension, arrhythmia, and increased intracranial, intraocular and gastric pressure, etc. This study carried out the change of serum potassium as an adverse effects of succinylcholine during endotracheal intubation in ED. A prospective, noncontrolled design was used to study serial serum potassium levels in pre- and postendotracheal intubation(5min) from February 1996 to August 1996. Succinycholine was selectively used in patient with a problem of difficult endotracheal intubation (alert to drowsy mental status with intact gag reflex). The dose of succinylcholine was 1.5 mg/kg and injected into intravenous line during preoxygenation with bag-valve-mask device. Student's two-tailed t-test was used and p-value was < 0.05. Among the total of 48 patients(male 27, female 21), the postintubation level of the serum potassium of 25 patients were increased and those of 21 persons were decreased compared with preintubation level. Two patients showed no change in amount. The average serum potassium indicated 3.7+/-.8 mEq/L before the injection of the succinylcholine and 3.8+/-.9 mEq/L 5 minutes after its injection. P-value showed more than 0.05 and as the result statistically there was no noteworthy difference. All patients were intubated within 30 sec and no patients were failed. We concluded that succinylcholine-assisted endotracheal incubation is a rapid and safe method as an endotracheal incubation practiced in ED and succinylcholin-induced hyperkalemia is minimal and no adverse effect.
Airway Management ; Anesthesia ; Arrhythmias, Cardiac ; Emergencies* ; Emergency Service, Hospital* ; Female ; Humans ; Hyperkalemia ; Hypotension ; Intubation, Intratracheal* ; Malignant Hyperthermia ; Neuromuscular Blockade ; Operating Rooms ; Potassium* ; Prospective Studies ; Succinylcholine*

In northern China, annual epidemics of acute-onset flaccid paralysis diagnosed clinically Guillain-Barre syndrome have been observed for at least 20 years. These patients had a distinctive pattern that shares clinical and cerebrospinal fluid findings with demyelinating Guillain-Barr syndrome. But it was different from Guillain-Barr syndrome physiologically and pathologically. Electrodiagnostic studies showed normal motor distal latencies and limb conduction velocity, but reduced compound muscle action potential amplitude. When sensory nerve action potentials are elicitable, F waves are within the range of normal. This disorder was named acute motor axonal neuropathy characterized pathologically by motor nerve fiber degeneration of variable severity and by sparing of sensory fibers. Recovery is usually complete. We experienced a case of acute axonal motor neuropathy, and reported the case with a review of literature.
Action Potentials ; Axons* ; Cerebrospinal Fluid ; China ; Extremities ; Guillain-Barre Syndrome ; Humans ; Nerve Fibers ; Paralysis

No abstract available.
Feeding Methods* ; Humans ; Infant, Newborn*

OBJECTIVE: To evaluate the correlation of level of leptin in cord blood and duration of labor. METHODS: Eighty-four pregnant women who had delivered during Jan. 2004-Jun. 2004. at the delivery unit of St. Mary's Hospital of Catholic University Medical College. We checked the level of leptin in cord blood, total duration of labor (cervix 3 cm-delivery of placenta), age of pregnant women, body weight before pregnancy, body weight before delivery, weight of the baby and placenta, head circumference, abdominal circumference, and height of the baby. Leptin was checked by ELISA. RESULTS: Cord blood leptin was in proportion to one's pregnancy duration (umbilical vein p<0.01, umbilical artery p<0.05), change of body weight (p<0.05), weight of placenta (p<0.01), weight of newborn (umbilical artery p<0.01, umbilical vein p<0.05), baby's abdominal circumference (umbilical vein p<0.01, umbilical artery p<0.05). Leptin was in inverse proportion to head circumference of new born infant in umbilical artery (p<0.01) and in umbilical vein (p<0.05). Level of leptin in umbilical vein was in proportion to duration of labor (p<0.05). When the labor duration exceeded 8 hours, leptin in cord blood decreased suddenly, but within 8 hours, their correlation coefficient showed a strong relationship (p<0.01) between the labor duration and leptin level in cord blood. CONCLUSION: Duration of labor affects the level of leptin in cord blood.
Arteries ; Body Weight ; Enzyme-Linked Immunosorbent Assay ; Female ; Fetal Blood* ; Head ; Humans ; Infant ; Infant, Newborn ; Leptin* ; Placenta ; Pregnancy ; Pregnant Women ; Umbilical Arteries ; Umbilical Veins ; Veins

We report on 2 siblings with a partial trisomy of 7q (7q22-->qter) and concomitant partial monosomy of 8p (8p23.3-->pter), which were shown by FISH using probes located at the telomere region of each chromosome. All the balanced translocation carriers (father and a sister) in this family had a normal phenotype. The 2 siblings with the same abnormal karyotype had similar multiple congenital anomalies and dysmorphic features. During the follow-up, the first male patient died in the neonatal period, but the female sibling is still alive at 2 years and 6 months of age.
Abnormal Karyotype ; Chromosome Deletion ; Female ; Follow-Up Studies ; Humans ; Male ; Phenotype ; Siblings ; Telomere ; Trisomy

OBJECTIVE: To evaluate the effect of uterine weight on short-term outcome of total laparoscopic hysterectomy (TLH) for benign gynecological conditions. METHODS: A retrospective medical records review of 265 cases of patients with TLH was performed. Patients included in this study underwent TLH as benign uterine disorders at Kangnam Sacred Heart Hostpital, Hallym University from January 2008 through June 2009. These patients were stratified into three groups; Group 1 patients with uterus weighing less than 180 g (n=60), Group2 patients with uterus weighing 180 g to 350 g (n=141), Group 3 patients with uterus weighing more than 350 g (n=64). The groups were compared as regard postoperative stay, operative time, estimated blood loss, hemoglobin change, conversion to open surgery, and postoperative complications. RESULTS: There was no significant difference in age, gravidity, body mass index, previous pelvic surgery and past medical history. The overall complication rates were not significantly different. But operative time prolonged as uterine weight increased. CONCLUSION: The TLH can be performed successfully in case of enlarged uterus. Therefore the enlarged uterus is not an absolute contraindication for TLH.
Body Mass Index ; Conversion to Open Surgery ; Gravidity ; Heart ; Hemoglobins ; Humans ; Hysterectomy ; Medical Records ; Operative Time ; Retrospective Studies ; Uterus