[Objective] The article analyzed the application of 'Disease Prevention'theory in the hypomenorrhea and provided treatment way for posterity doctor treating the disease. [Method] In this chapter it elaborated the pathogenesis of hypomenorrhea about traditional Chinese medicine and modern medicine. At the same time, it elaborated hypomenorrhea's prevention and treatment from the following aspects:prevention of disease which did not appear, prevention of disease which appeared from worsening,and prevention of disease which was cured from reoccurring to explore the treatment effect and advantage.[Result] The hypomenorrhea was harmful and its incidence rate to a trend of annual increase in recent years. To put'Disease Prevention'theory in the whole diagnosis process had a significant clinical curative effect. [Conclusion] In this paper, starting from the'Disease Prevention'theory treatment of the disease has some practical value, which is worthy of popularization and application.