No abstract available.
Diabetes Insipidus* ; Empty Sella Syndrome*

No abstract available.
Cushing Syndrome* ; Empty Sella Syndrome* ; Hyperplasia*

No abstract available.
Empty Sella Syndrome ; Hypoglycemia ; Insulin ; Receptor, Insulin

Empty sella syndrome shows partial or total loss of pituitary tissue and enlargement of the sella turcica due to incomplete diaphragm sellae and herniation of subarachnoid space through the defect. This syndrome usually occurs in obese, hypertensive, and cephalgic women, but it is often asymptomatic. We report a case of primary empty sella syndrome diagnosed by magnetic resonance imaging scan with literature review in 57-year-old female patient who had had unilateral cataract operation and presented with bilateral visual disturbance and bitemporal hemianopsia at postoperative 2 months.
Cataract ; Diaphragm ; Empty Sella Syndrome* ; Female ; Hemianopsia ; Humans ; Magnetic Resonance Imaging ; Middle Aged ; Sella Turcica ; Subarachnoid Space

OBJECTIVE: To investigate the morphometric characteristics of the pituitary gland and diaphragma sellae in Korean adults. METHODS: Using the 33 formaline fixed adult cadavers (23 male, 10 female), the measurements were taken at the diaphragma sellae and pituitary gland. The authors investigated the relationship between dura and structures surrounding pituitary gland, morphometric aspects of pituitary gland and stalk, and morphometric aspect of central opening of diaphragma sellae. RESULTS: The boundary between the lateral surface of pituitary gland and the medial wall of cavernous sinus was formed by the thin dural layer and pituitary capsule. The pituitary capsule adherent tightly to the pituitary gland was observed to continue from the diaphragma sellae. Mean width, length, and height of the pituitary gland were 14.3 +/- 2.1, 7.9 +/- 1.3, and 6.0 +/- 0.9 mm in anterior lobes, and 8.7 +/- 1.7, 2.9 +/- 1.1, and 5.8 +/- 1.0 mm in posterior lobes, respectively. Although all dimensions of anterior lobe in female were slightly larger than those in male, statistical significance was noted in only longitudinal dimension. The ratio of posterior lobe to the whole length of pituitary gland was about 27%. The mean thickness of pituitary stalk was 2 mm. The diaphragmal opening was 5 mm or more in 26 (78.8%) of 33 specimen. The opening was round in 60.6% of the specimen, and elliptical oriented in an anterior-posterior or transverse direction in 39.4%. CONCLUSION: These results provide the safe anatomical knowledge during the transsphenoidal surgery and may be helpful to access the possibility of the development of empty sella syndrome.
Adult ; Cadaver ; Cavernous Sinus ; Diaphragm ; Empty Sella Syndrome ; Female ; Formaldehyde ; Humans ; Male ; Pituitary Gland

Primary empty sella syndrome is a phenomenon caused by cerebrospinal fluid filling resulting from the herniation of the subarachnoid space within the sella. The pituitary function of primary empty sella syndrome is usually normal. But sometimes this syndrome causes some degree of pituitary dysfunction associated with hypersecretion or deficiency of pituitary hormone. Central diabetes insipidus with primary empty sella syndrome is rarely reported. Furthermore, most of those cases are accompanied by other pituitary dysfunction. We report here on a 35-year-old female who suffered from polyuria, polydipsia since childhood. She was diagnosed with central diabetes insipidus with primary empty sella syndrome. She had no anterior pituitary dysfunction except mild hyperprolactinemia.
Adult ; Cerebrospinal Fluid ; Diabetes Insipidus, Neurogenic* ; Empty Sella Syndrome* ; Female ; Humans ; Hyperprolactinemia ; Polydipsia ; Polyuria ; Subarachnoid Space

Empty Sella Syndrome ; diagnosis ; Female ; Humans ; Middle Aged ; Petrosal Sinus Sampling ; methods ; Pituitary Neoplasms ; diagnosis

Acromegaly is a disorder caused by hypersecretion of growth hormone (GH) and insulin-like growth factor-1 (IGF-1). The most common cause of acromegaly is a pituitary GH-producing adenoma. Complete or partial disappearance of the adenoma, probably as a result of hemorrhage or infarction, may lead to empty sella. A case of acromegaly with empty sella syndrome has rarely been reported in Korea. It has been suggested that acromegaly might be associated with the incidence of colon neoplasm. Here, we describe a case of acromegaly with empty sella syndrome in a patient who was diagnosed with colon cancer.
Acromegaly ; Adenoma ; Colon ; Colonic Neoplasms ; Empty Sella Syndrome ; Growth Hormone ; Hemorrhage ; Humans ; Incidence ; Infarction ; Korea

The empty sella syndrome is characterized by obesity, frequent pregnancy, headache and high blood pressure, but its exact cause remains unknown. Usually the incomplete diaphragmatic sella has been considered as the cause of the empty sella syndrome, but some authors recently have suggested that the antipituitary antibody way be related to development of pituitary atrophy and the pituitary empty sella syndrome, and thus it may be clinically useful as screening test for the empty sella syndrome. We experienced two empty sella syndromes associated Graves disease and applied the antipituitary antibody as the diagnostic tool of the empty sella syndrome. But none of this two patients had antipituitary antibody and we report these cases with reviews of literatures.
Atrophy ; Empty Sella Syndrome ; Graves Disease ; Headache ; Humans ; Hypertension ; Mass Screening ; Obesity ; Pregnancy

The empty sella syndrome is defined as the intrasella herniation of the chiasmal cistern resulting from a congenitally incompetent diaphragma sellae. In idiopathic or primary empty sella syndrome, sella remodelling occurs as a result of an anatomical variation in the diaphragma sella. The secondary empty sella syndrome occurs following surgery or irradiation of an intrasellar lesion. Empty sella syndrome is known to be rarely associated with Cerebrospinal fluid (CSF) rhinorrhea. We experienced a case of secondary empty sella symdrome with CSF rhinorrhea in a 56-year old female who complained of persistent rhinorrhea through the roof of the sphenoid sinus after brain surgery due to meningioma. The CSF rhinorrhea was treated successfully with transseptal trans-sphenoidal approach.
Brain ; Cerebrospinal Fluid Rhinorrhea* ; Cerebrospinal Fluid* ; Empty Sella Syndrome* ; Female ; Humans ; Meningioma ; Middle Aged ; Sphenoid Sinus