Abdomen, Acute ; diagnosis ; Adult ; Humans ; Male ; Pancreatic Neoplasms ; diagnosis ; Shock, Hemorrhagic ; diagnosis ; Young Adult

OBJECTIVETo investigate the clinical predictors of cytomegalovirus (CMV) infection after liver transplantation.

METHODSThe clinical data of 182 patients (146 male and 36 female with a mean age of (50 ± 7) years) receiving liver transplantation in Beijing Chaoyang Hospital between January 2004 and December 2008 were retrospectively analyzed.All patients were divided into two groups, namely the CMV infection group (n=24) and the control group (n=158). Logistic regression was used to identify the predictive factors of postoperative CMV infection.

RESULTSAccording to univariate analysis results, the factors for CMV infection were acute liver failure (P=0.032), MELD score ≥ 30 (P=0.001), liver retransplantation (P=0.002), acute rejection (P=0.000) and delayed graft function (P=0.022). According to multi-analysis results, MELD score ≥ 30 (P=0.037, 95%CI:1.194-271.461) and acute rejection (P=0.033, 95%CI:1.179-51.863) were proved to be independent predictors by multivariate analysis.

CONCLUSIONThe study indicates that MELD score ≥ 30 and acute rejection are the independent predictors of CMV infection.

Adult ; Beijing ; Cytomegalovirus Infections ; diagnosis ; End Stage Liver Disease ; diagnosis ; Female ; Graft Rejection ; Humans ; Liver Transplantation ; adverse effects ; Logistic Models ; Male ; Middle Aged ; Multivariate Analysis ; Postoperative Complications ; virology ; Reoperation ; Retrospective Studies ; Severity of Illness Index