1.Rapid visual recovery after inadvertent embolization of retinal arterioles with triamcinolone acetonide
Philippine Journal of Ophthalmology 2010;35(2):73-75
Objective To describe a case of acute visual loss due to retinal arteriolar embolization caused by transeptal triamcinolone-acetonide injection, with rapid visual recovery following immediate intervention. Methods This is a case report. Results A 39-year-old female developed loss of vision (no light perception) after transeptal triamcinolone-acetonide injection. Examination revealed yellowish, particulate emboli within the retinal arterioles. Strategies to relieve the obstructed vessel (anterior-chamber paracentesis, intraocular-pressurelowering medications, and ocular massage) were immediately performed. Full recovery of vision occurred within 24 hours. Conclusion Retinal vascular embolization should be suspected when there is loss of vision after corticosteroid injection. Immediate ocular decompression may lead to rapid improvement and favorable visual outcomes.
2.Inflammatory pigment epithelial detachment associated with Blastocystis hominis
Ellen N. Yu-Keh ; Felipe I. Tolentino ; Amadeo A.S. Veloso Jr
Philippine Journal of Ophthalmology 2010;35(1):40-42
Objective:
To describe a case of inflammatory pigment epithelial detachment (PED)
presumed to be secondary to the amoeba Blastocystis hominis.
Methods:
This is an interventional case report.
Results:
A 46-year-old male complained of visual distortion in the left eye for 7
months. Examination revealed the presence of a subretinal cystic lesion on
the fovea. Optical coherence tomography demonstrated a PED with a
hyperreflective lesion over the detached retinal pigment epithelium (RPE).
Work-up included a fecalysis, which revealed the presence of Blastocystis hominis.
The patient was treated with oral metronidazole. RPE detachment resolved
after treatment with no recurrence in 30 months of follow-up.
Conclusion
Intestinal parasitic infection may be associated with retinal disease and
should be included in the differential diagnosis of PED when OCT reveals a
hyperreflective lesion.
Blastocystis hominis
3.Pegaptanib sodium for macular edema due to retinal-vein occlusion among patients intolerant to intravitreal triamcinolone acetonide
Ellen N. Yu ; Pik Sha Chan ; Amadeo A.S. Veloso ; Harvey S Uy
Philippine Journal of Ophthalmology 2010;35(2):79-81
Objective:
To report the efficacy and safety of intravitreal pegaptanib sodium (IVP)
on macular edema (ME) due to branch retinal-vein occlusion (BRVO) among
patients intolerant to intravitreal triamcinolone acetonide (IVTA).
Methods:
Four eyes with ME due to BRVO were included in this interventional case
series. The main outcome measures were best-corrected visual acuity (BCVA),
central macular thickness (CMT), intraocular pressure (IOP), and adverse
effects.
Results:
There was a significant decrease in mean CMT from 524.50 ± 141.12 to
293.75 ± 130.75 microns (p = 0.009) after IVP injection. BCVA improved in all
4 eyes after IVP. Mean IOP after IVP was 13.60 ± 3.21. No ocular or systemic
complications were observed.
Conclusion
IVP appears to be safe and effective in decreasing retinal thickness and
improving VA in eyes with ME due to BRVO. IVP is a potential treatment for
eyes that are intolerant to IVTA.
Macular Edema