1.Factors associated with side effects of COVID-19 vaccine in Indonesia
Johan WIBOWO ; Rivaldo Steven HERIYANTO ; Felix WIJOVI ; Devina Adella HALIM ; Claudia CLAUDIA ; Elizabeth MARCELLA ; Billy SUSANTO ; Michele INDRAWAN ; Nadia Khoirunnisa HERYADI ; Michelle IMANUELLY ; Jonathan Juniard ANURANTHA ; Timotius Ivan HARIYANTO ; Chintya MARCELLIN ; Terry Devita SINAGA ; Saraswati Anindita RIZKI ; Novia SIETO ; Jeremia Immanuel SIREGAR ; Nata Pratama Hardjo LUGITO ; Andree KURNIAWAN
Clinical and Experimental Vaccine Research 2022;11(1):89-95
Purpose:
As coronavirus disease 2019 (COVID-19) continues to spread rapidly causing approximately 186 million confirmed cases around the world, the urgency to reach herd immunity through vaccination is increasing. However, vaccine safety is a top priority to limit the occurrence of adverse events. Henceforth, this study aims to recognize and perceive COVID-19 vaccine safety in Indonesia during the pandemic.
Materials and Methods:
This is a cross-sectional study and was conducted in Indonesia during the COVID-19 pandemic using an online survey of demographic information and a qualitative questionnaire. Responses were recorded and the association between demographic characteristics from survey questions was tested using chi-square with a risk estimate and 95% confidence interval.
Results:
A total of 311 participants from 33 out of 34 provinces in Indonesia participated in this study. Recorded responses showed multiple side effects of the COVID-19 vaccine both short- and long-term experienced by the participants. Significant associations were found between demographic factors and COVID-19 vaccine side effects such as female gender with short-term puncture site (odds ratio [OR], 0.463; 95% confidence interval [CI], 0.263–0.816) and short-term other reactions (OR, 0.463; 95% CI, 0.263–0.816), domicile outside Java island with long-term puncture site (OR, 4.219; 95% CI, 1.401–12.701) and immune reactions (OR, 3.375; 95% CI, 1.356–8.398), also between married marital status and long-term vagal reaction (OR, 4.655; 95% CI, 1.321–16.409).
Conclusion
Gender, domicile and marital status factors were associated with COVID-19 vaccine side effects in Indonesian people.
Result Analysis
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