We reported two cases of elephantiasis neurofibromatosa in a family. The first case was the son of the second case. Both patients showed huge masses and bone changs. They were treated by surgical excision due to functional and cosmetic problems. The histopathologic findings of the two cases were consistent with neurofibroma.
Elephantiasis* ; Humans ; Neurofibroma ; Neurofibromatoses*

The epidemiological surveys and inquest of retrospective data were conducted from 2002 to 2003 in Thua Thien – Hue, results showed that there were 4 patients with chronic complications of lymphatic filariasis in Hue city, Huong Tram district and Nam Dong district. Then the surveys were carried out in 7 communes with 2003 blood firms were taken and examined for microfilariae from November 2002 to April 2003. No positive slide has been found so far
Elephantiasis, Filarial ; Epidemiologic Studies ; Disease

Elephantiasis neurofibromatosa is the clinical subtype of neurofibromatosis and this clinically represents as a large, ill-defined, soft mass with soft tissue overgrowth and hairy pigmented patches. Histopathologically, an infiltrating and well-demarcated mass that is not encapsulated and the mass is composed of proliferating spindle-shaped cells can be observed in the dermis and subcutis. Mitotic activities should not exist. We herein report on two cases of elephantiasis neurofibromatosa that were treated with surgery. Both patients had had difficulty in walking due to a huge mass that had been on their left legs for more than 20 years. After surgery, they reported improvement of their ambulation.
Dermis ; Elephantiasis ; Humans ; Leg ; Neurofibromatoses ; Walking

In this survey, night blood firms were taken from 2,389 people in 2 communes of Lam Dong province: Tien Hoang (Cat Tien district) and Da Don ( Lam Ha district); and 2 communes of Dak Lak province: Eatrang (M’drak district) and Krongana (Buon Don district). No microlymphrea has been found. An entomological survey was also conducted in 4 same communes, showed that Culex quinquefasciantus and Culex vishnui occupied a high proportions among the collected mosquitoes. LF wasn’t found in the dissection of 461 mosquitoes
Elephantiasis, Filarial ; Epidemiologic Studies ; Disease ; epidemiology

An epidemiological survey for lymphatic filariasis was conducted in Nov.2001 in 4 communes of GiaLai and KonTum provinces. Blood was taken at night for detecting filarium,and mosquitoes were caugh for surveying entomologically.No microfilarium was detected in blood but a high rate of Culex quinquefasciatus,Culex vishnui, Culex puscocephalia was found. Dissection performed on 681 invidual mosquitoes did not show micofilarium
Elephantiasis, Filarial ; epidemiology ; diagnosis ; blood ; mosquitoes ;

We report a case of elephantiasis neurofibromatosa in a 50-year-old female patient treated by in walking excision. She had difficulty in walking due to a huge mass on the abdomen. After surgical excision, she is leading a normal life and is very satisfied.
Abdomen ; Elephantiasis* ; Female ; Humans ; Middle Aged ; Neurofibromatoses* ; Walking

Acupuncture Points ; Acupuncture Therapy ; Adult ; Elephantiasis ; therapy ; Female ; Humans

In mid-1987 a baseline microfilarial prevalence survey was conducted among five villages in the Mt Bosavi region of the Southern Highlands Province of Papua New Guinea. Through use of the Nucleopore filtration technique, it was determined that 48% of villagers had detectable microfilaraemia. The highest prevalence was documented in Fogomaiyu, where the microfilaraemia rate was 92%. On the basis of this initial survey and the expressed interest of the community, the Division of Health in the Southern Highlands Province undertook an integrated community-based pilot control program. The project used two principal control methods: (a) drug treatment with low-dose diethylcarbamazine citrate (DEC) distributed to the community weekly and (b) vector control with permethrin-impregnated bednets. Results six months after the intervention indicate that the program was successful in reducing microfilaraemia at Fogomaiyu village from 92% to 6%. The reduction is principally related to the effects of DEC, although the bednets, by limiting vector-person contact, are expected to reduce the incidence of both filariasis and malaria.
Adolescent ; Altitude ; Bedding and Linens ; Community Participation ; Elephantiasis, Filarial - epidemiology

Elephantiasis neuromatosa is one of 3 types of cutaneous tumors in Von Recklinghausen's disease. This 28 year-old male patient visited for adult-fist sized tumor associated with hairy pigmented patch on right antecubital fossa, and various sized tumors and cafe-au-lait spots on whole body of about 27 years duration. Past history was noncontributory. Family history revealed that his father and son had similar manifestations. Laboratory findings were noncontributory. Histopathology of cafe-au-lait spot and hairy pigmented patch revealed increase of melain in basal cell layer of the epidermis and increase in the concentratiton and activity of the melanocytes in basal cell layer of the epidermis. Histopathology of the mass revealed slightly thin, wavy fibrs lying in loosely textured strands extending in varying directions and a fairly large number of nuclei that are ovel to spindle-shaped and fairly uniform in size.
Adult ; Cafe-au-Lait Spots ; Deception ; Elephantiasis* ; Epidermis ; Fathers ; Humans ; Male ; Melanocytes ; Neurofibromatosis 1

We report herein a case of elephantiasis neuromatosa seen in neurofibromatosis patient, who was a 33-year-old male and had been diagnosed at the age of 13. Since that time on, small nodule present on the mid-back area led to develop grotesquely large, dark-brown colored, flabby mass with thick verucoid skin change, measuring about 30 * 20cm in size. Histopathologic examination of excised mass demonstrated moderate hyperplasia of epidermis and typical neurofibroma findings with soft tissue and fibrous tissue overgrowth, but no atypical cells. The electron microscopic study showed many perineurial cells surrounded by the continuous bssal lamina of fibroblsst in the dermal lesion and numerous giant pigmented granules in melanocyte and basal keratinocyte in the cafe-au-lait spot.
Adult ; Cafe-au-Lait Spots ; Elephantiasis* ; Epidermis ; Humans ; Hyperplasia ; Keratinocytes ; Male ; Melanocytes ; Neurofibroma ; Neurofibromatoses ; Skin