Background/Objective: There is a deep concern about the rapid rise in resistance of bacteria to antimicrobial agents. Methicillin-resistant Staphylococcus aureus (MRSA) which pose challenges to the medical community. This study aimed to determine the prevalence and sensitivity pattern of Methicillin-Resistant Staphylococcus Aureus (MRSA) in a tertiary hospital in Cebu City from January 1, 2007 to December 31, 2010. Methods: Charts of patients with MRSA growths were reviewed upon their admission. The sensitivity pattern, demographic profile and risk factors were noted. Results: Out of the 637 isolates of Staphylococcus aureus, MRSA had a prevalence rate of 38.6% (n=246), while Methicillin Sensitive Staphylococcus aureus (MSSA) had 61.4% (n=391). The prevalence rate of health-care associated MRSA was 2% (n=5). The majority of the specimens sent for culture were wound/abscess (70% of pediatric and 76% of adult patients isolates). All MRSA growths were resistant to penicillin G, ampicillin, oxacillin, cefuroxime and amikacin. Local MRSA strains were still susceptible to ciprofloxacin (82.3%), clindamycin (90.6%), erythromycin (91.5%), and sulfamethoxazole-trimethoprim (85.9%). There was no resistance to linezolid and vancomycin. Vancomycin-resistant Staphylococcus aureus was not isolated. The mortality rate on both pediatric and adult population was 2.1% and 4.8%, respectively. Conclusion The prevalence of MRSA is increasing. Clindamycin, erythromycin, sulfamethoxazole- trimethoprim and vancomycin are excellent treatment options treat MRSA.
Methicillin-Resistant Staphylococcus aureus ; Staphylococcus aureus ; Vancomycin

Adult ; Anticarcinogenic Agents ; therapeutic use ; Breast Neoplasms ; drug therapy ; pathology ; Disease Progression ; Female ; Humans ; Interdisciplinary Communication ; Neoplasm Staging ; Pregnancy ; Pregnancy Complications, Neoplastic ; drug therapy ; pathology ; Treatment Outcome

INTRODUCTIONPosterior segment involvement has been described to be associated with central nervous system involvement in sarcoidosis as a result of direct sarcoid tissue infiltration or mass effect of a cerebral lesion. However, isolated intermediate uveitis occurring concurrently with central nervous system involvement prior to extensive systemic disease is rare.

CLINICAL PICTUREWe describe a patient with neuro-ophthalmic manifestations of intermediate uveitis and an enhancing basal ganglia lesion at initial presentation, in the absence of extensive systemic disease.

TREATMENTHe was treated with high-dose systemic steroids which was progressively tailed down over 6 months.

OUTCOMEThere was prompt resolution of vitritis with good preservation of visual acuity.

CONCLUSIONThe difficulties of the initial diagnosis of sarcoidosis and the indications for initiation of steroid therapy are illustrated. We use this case to emphasise the need for a high clinical suspicion of sarcoidosis in the presence of similar unusual and seemingly unrelated combinations of neurological manifestations so as to facilitate the prompt institution of appropriate treatment when indicated.

Adult ; Angiography ; Basal Ganglia ; diagnostic imaging ; physiopathology ; Brain Ischemia ; complications ; diagnosis ; Comorbidity ; Diagnosis, Differential ; Humans ; Magnetic Resonance Imaging ; Male ; Sarcoidosis ; complications ; diagnosis ; Time Factors ; Tomography, X-Ray Computed ; Uveitis ; complications ; diagnosis