1.Successful High-Dose Radiation Treatment for Chemo-Resistant Oral Squamous Cell Carcinoma in a Kindler’s Syndrome Patient
Yuka KIMURA ; Atsushi TANEMURA ; Yuma HANAOKA ; Eiji KIYOHARA ; Mari WATAYA-KANEDA ; Manabu FUJIMOTO ; Katsuto TAMAI ; Keisuke TAMARI ; Yuji SEO ; Kazuhiko OGAWA
Annals of Dermatology 2021;33(4):382-384
2.Successful High-Dose Radiation Treatment for Chemo-Resistant Oral Squamous Cell Carcinoma in a Kindler’s Syndrome Patient
Yuka KIMURA ; Atsushi TANEMURA ; Yuma HANAOKA ; Eiji KIYOHARA ; Mari WATAYA-KANEDA ; Manabu FUJIMOTO ; Katsuto TAMAI ; Keisuke TAMARI ; Yuji SEO ; Kazuhiko OGAWA
Annals of Dermatology 2021;33(4):382-384
3.Efficacy of TachoSil, a Fibrin-Based Hemostat, for Anterior Lumbar Spine Surgery.
Jo WATANABE ; Seiji OHTORI ; Sumihisa ORITA ; Kazuyo YAMAUCHI ; Yawara EGUCHI ; Yasuchika AOKI ; Junichi NAKAMURA ; Miyako SUZUKI ; Kazuhide INAGE ; Jun SATO ; Yasuhiro SHIGA ; Koki ABE ; Kazuki FUJIMOTO ; Hirohito KANAMOTO ; Eiji HANAOKA ; Kazuhisa TAKAHASHI
Asian Spine Journal 2016;10(5):930-934
STUDY DESIGN: Retrospective case series. PURPOSE: To examine the efficacy of TachoSil for vessel injury in 6 patients who underwent anterior lumbar fusion surgery (ALF). OVERVIEW OF LITERATURE: ALF for the lumbar spine has a high rate of success, although intraoperative concerns and iatrogenic complications are known, and injury of a major vessel is sometimes a complication. The efficacy of TachoSil, a fibrin-based hemostat, has been reported for several types of surgery; however, use of TachoSil for ALF surgery has not been described. Here, we report on the efficacy of TachoSil in 6 patients, who underwent ALF after vascular surgeons having difficulty in repairing vessels. METHODS: Two man and 4 women with average age of 50.8±10.9 (mean±standard deviation) were diagnosed with a vertebral tumor (2 patients), L4 degenerative spondylolisthesis (2 patients), and L5 spondylolytic spondylolisthesis (2 patients) and underwent ALF. The blood vessels injured included the common iliac vein in 2 patients and a branch of a segmental artery from the aorta in 4 patients. We consulted a vascular surgeon to suture or repair the vessels during surgery, and although the vascular surgeon attempted to address the injuries, suturing or repair was not possible in these cases. For this reason, we used TachoSil to repair the injury in the vessels walls or to stop the bleeding. RESULTS: Time to pressure hemostasis using TachoSil was 34±12 minutes, and total blood loss was 1,488±1,711 mL. Nevertheless, all vessel injuries were controlled by the use of TachoSil. CONCLUSIONS: We recommend the use of TachoSil for vessel injuries that vascular surgeons cannot suture or repair during ALF surgery.
Aorta
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Arteries
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Blood Vessels
;
Female
;
Hemorrhage
;
Hemostasis
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Humans
;
Iliac Vein
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Retrospective Studies
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Spine*
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Spondylolisthesis
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Surgeons
;
Sutures
4.Conservative and Surgical Treatment Improves Pain and Ankle-Brachial Index in Patients with Lumbar Spinal Stenosis.
Seiji OHTORI ; Masaomi YAMASHITA ; Yasuaki MURATA ; Yawara EGUCHI ; Yasuchika AOKI ; Hiromi ATAKA ; Jiro HIRAYAMA ; Tomoyuki OZAWA ; Tatsuo MORINAGA ; Hajime ARAI ; Masaya MIMURA ; Hiroto KAMODA ; Sumihisa ORITA ; Masayuki MIYAGI ; Tomohiro MIYASHITA ; Yuzuru OKAMOTO ; Tetsuhiro ISHIKAWA ; Hiroaki SAMEDA ; Tomoaki KINOSHITA ; Eiji HANAOKA ; Miyako SUZUKI ; Munetaka SUZUKI ; Takato AIHARA ; Toshinori ITO ; Gen INOUE ; Masatsune YAMAGATA ; Tomoaki TOYONE ; Gou KUBOTA ; Yoshihiro SAKUMA ; Yasuhiro OIKAWA ; Kazuhide INAGE ; Takeshi SAINOH ; Kazuyo YAMAUCHI ; Kazuhisa TAKAHASHI
Yonsei Medical Journal 2013;54(4):999-1005
PURPOSE: The pathological mechanism of lumbar spinal stenosis is reduced blood flow in nerve roots and degeneration of nerve roots. Exercise and prostaglandin E1 is used for patients with peripheral arterial disease to increase capillary flow around the main artery and improve symptoms; however, the ankle-brachial index (ABI), an estimation of blood flow in the main artery in the leg, does not change after treatment. Lumbar spinal nerve roots contain somatosensory, somatomotor, and unmyelinated autonomic nerves. Improved blood flow by medication with prostaglandin E1 and decompression surgery in these spinal nerve roots may improve the function of nerve fibers innervating muscle, capillary, and main vessels in the lower leg, resulting in an increased ABI. The purpose of the study was to examine whether these treatments can improve ABI. MATERIALS AND METHODS: One hundred and seven patients who received conservative treatment such as exercise and medication (n=56) or surgical treatment (n=51) were included. Low back pain and leg pain scores, walking distance, and ABI were measured before treatment and after 3 months of conservative treatment alone or surgical treatment followed by conservative treatment. RESULTS: Low back pain, leg pain, and walking distance significantly improved after both treatments (p<0.05). ABI significantly increased in each group (p<0.05). CONCLUSION: This is the first investigation of changes in ABI after treatment in patients with lumbar spinal stenosis. Improvement of the spinal nerve roots by medication and decompression surgery may improve the supply of blood flow to the lower leg in patients with lumbar spinal stenosis.
Adult
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Aged
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Aged, 80 and over
;
Alprostadil/therapeutic use
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*Ankle Brachial Index
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Decompression, Surgical/methods
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Female
;
Humans
;
Low Back Pain/drug therapy/physiopathology/surgery/*therapy
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Lumbar Vertebrae/physiopathology/*surgery
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Male
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Middle Aged
;
Pain/surgery
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Spinal Nerve Roots/physiopathology
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Spinal Stenosis/physiopathology/*surgery/*therapy
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Treatment Outcome
5.Incidence of Nocturnal Leg Cramps in Patients with Lumbar Spinal Stenosis before and after Conservative and Surgical Treatment.
Seiji OHTORI ; Masaomi YAMASHITA ; Yasuaki MURATA ; Yawara EGUCHI ; Yasuchika AOKI ; Hiromi ATAKA ; Jiro HIRAYAMA ; Tomoyuki OZAWA ; Tatsuo MORINAGA ; Hajime ARAI ; Masaya MIMURA ; Hiroto KAMODA ; Sumihisa ORITA ; Masayuki MIYAGI ; Tomohiro MIYASHITA ; Yuzuru OKAMOTO ; Tetsuhiro ISHIKAWA ; Hiroaki SAMEDA ; Tomoaki KINOSHITA ; Eiji HANAOKA ; Miyako SUZUKI ; Munetaka SUZUKI ; Takato AIHARA ; Toshinori ITO ; Gen INOUE ; Masatsune YAMAGATA ; Tomoaki TOYONE ; Gou KUBOTA ; Yoshihiro SAKUMA ; Yasuhiro OIKAWA ; Kazuhide INAGE ; Takeshi SAINOH ; Jun SATO ; Kazuyo YAMAUCHI ; Kazuhisa TAKAHASHI
Yonsei Medical Journal 2014;55(3):779-784
PURPOSE: To examine the effects of conservative and surgical treatments for nocturnal leg cramps in patients with lumbar spinal stenosis (LSS). Nocturnal leg cramps is frequently observed in patients with peripheral neuropathy. However, there have been few reports on the relationship between nocturnal leg cramps and LSS, and it remains unknown whether conservative or surgical intervention has an impact on leg cramps in patients with LSS. MATERIALS AND METHODS: The subjects were 130 LSS patients with low back and leg pain. Conservative treatment such as exercise, medication, and epidural block was used in 66 patients and surgical treatment such as decompression or decompression and fusion was performed in 64 patients. Pain scores and frequency of nocturnal leg cramps were evaluated based on self-reported questionnaires completed before and 3 months after treatment. RESULTS: The severity of low back and leg pain was higher and the incidence of nocturnal leg cramps was significantly higher before treatment in the surgically treated group compared with the conservatively treated group. Pain scores improved in both groups after the intervention. The incidence of nocturnal leg cramps was significantly improved by surgical treatment (p=0.027), but not by conservative treatment (p=0.122). CONCLUSION: The findings of this prospective study indicate that the prevalence of nocturnal leg cramps is associated with LSS and severity of symptoms. Pain symptoms were improved by conservative or surgical treatment, but only surgery improved nocturnal leg cramps in patients with LSS. Thus, these results indicate that the prevalence of nocturnal leg cramps is associated with spinal nerve compression by LSS.
Adult
;
Aged
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Aged, 80 and over
;
Decompression, Surgical
;
Female
;
Humans
;
Leg/*pathology
;
Low Back Pain/epidemiology/etiology
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Male
;
Middle Aged
;
Pain/*epidemiology/*etiology
;
Prospective Studies
;
Questionnaires
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Spinal Stenosis/*complications/*physiopathology/surgery