1.Case report : Calvarial tuberculosis.
Efraim Pacana Culminas ; Lucy Kathrina Banta-Banzali
The Philippine Children’s Medical Center Journal 2022;18(2):114-120
Skeletal tuberculosis accounts for 1-3% of TB cases, and of these only 0.2-1.3% had calvarial involvement. 1 Calvarial TB is most likely secondary to a primary focus. Diagnosis is confirmed through findings of Mycobacterium tuberculosis via microbiological, histopathological or cytopathological methods. This case report presents
Primary Calvarial Tuberculosis in a five-year old male presenting with multiple cranial masses and initial diagnosis of Langerhans cell histiocytosis (LCH).
Human ; Male ; Child Preschool (a Child Between The Ages Of 2 And 5) ; Tuberculosis ; Mycobacterium Tuberculosis ; Tuberculosis, Pulmonary
2.Comparison of the anxiety levels in children with Acute Lymphoblastic Leukemia and their well siblings using the child drawing: Hospital manual.
Efraim P. Culminas ; Angie Sievert-Fernandez ; Michael M. Resurreccion
Journal of the Philippine Medical Association 2018;97(1):1-14
OBJECTIVES:
The study aims to determine and compare the anxiety of children with acute lymphoblastic leukemia
and their well siblings based on Child drawing: Hospital manual and to identify factors associated with the level
of anxiety.
METHODS:
A prospective cross-sectional study was done in the hematology-oncology outpatient clinic and
private clinics of hema-oncology specialist in tertiary pediatric hospitals. The study included children five to
eleven years old diagnosed with Acute Lymphoblastic Leukemia (ALL) and their well siblings.
RESULTS:
A total of forty dyads of participants were included in the study. ALL patients presented higher anxiety
scores than their siblings. However, this was not statistically significant. There is a weak direct correlation
between overall anxiety scores of ALL patients and their siblings (p = 0.017). There is insufficient evidence to
demonstrate an association between select clinical factors with anxiety scores. The linear regression model
showed 49.77% in the variation of the anxiety scores.
CONCLUSIONS:
There is a direct correlation between overall anxiety scores of ALL patients and their siblings.
There is a positive association with larger family size and child’s response to sibling’s illness. A larger families
are likely to have a healthier environment. The study showed low to average anxiety levels among participants
which may be related to quality of care and support given by the institution and inherent resiliency of the family.
RECOMMENDATIONS
Future research should aim to develop psychological, emotional and behavioral programs in
partnerships with families and other social support groups. Future studies should examine other possible
cultural and psychodynamic factors prevalent in Filipino Family.
Human
;
Anxiety
;
Precursor Cell Lymphoblastic Leukemia-lymphoma
3.Comparison of the anxiety levels in children with acute lymphoblastic leukemia and their well siblings using the child drawing: Hospital manual”.
Efraim P. Culminas ; Angie Sievert-Fernandez ; Michael M. Resurreccion
The Philippine Children’s Medical Center Journal 2019;15(2):45-56
OBJECTIVES:
The study aims to determine and compare the anxiety of children with acute
lymphoblastic leukemia (ALL) and their well siblings based on Child drawing: Hospital manual and to
identify factors associated with the level of anxiety.
METHODS:
A prospective cross-sectional study was done in tertiary pediatric hospitals which
included children aged five to eleven years old diagnosed with ALL and their well siblings.
RESULTS:
A total of forty dyads of participants were studied. ALL patients presented higher anxiety
scores than their siblings, but this was not statistically significant. There is a weak direct correlation
between overall anxiety scores of ALL patients and their siblings (p = 0.017). There is insufficient
evidence for an association between select clinical factors with anxiety scores. The linear regression
model explained 49.77% in the variation of the anxiety scores but was not statistically significant.
CONCLUSIONS:
There is a direct correlation between overall anxiety scores of ALL patients and
their siblings. There is also a positive association with larger family size and child‘s response to
sibling‘s illness. Larger families are likelier to have a healthier environment. The study also showed
low to average anxiety levels among participants which may be related to quality of care and support
given by the institution and inherent resiliency of the family.
RECOMMENDATIONS
Future research should aim to develop programs in partnership with
families and other social support groups and explore the effectiveness of these interventions. Further
studies should examine other possible cultural and psychodynamic factors prevalent in Filipino
Family.
Anxiety
;
Siblings
4.Co-infection of Coronavirus Omicron variant and Salmonella Meningoencephalitis
Efraim Culminas ; Lucy Kathrina Banta- Banzali ; Jay Ron Padua
The Philippine Children’s Medical Center Journal 2023;19(2):88-93
It has been considered that viral infections predispose patients to bacterial
infections due to immunosuppression.3 However, it is still unclear what exact roles co-infections
play in patients with COVID-19 infection1. Centers for Disease Control and Prevention defines co
-infection as an infection concurrent with the initial infection. This report discusses a case of
meningoencephalitis presenting with seizures. Notable in this case was the detection of
SARS-CoV-2 RNA and Salmonella in the CSF.
Coronavirus