1.Fetal goiter conservatively monitored during the prenatal period associated with maternal and neonatal euthyroid status.
Jose Ferreira Gomes NETO ; Edward ARAUJO JUNIOR ; Jesus Irajacy Fernandes COSTA ; Daniel Aguiar DIAS ; Lindemberg Barbosa AGUIAR ; Francisco Herlanio Costa CARVALHO
Obstetrics & Gynecology Science 2016;59(1):54-57
Congenital goiter is considered a rare occurrence, and may be related to hypothyroidism, hyperthyroidism, or euthyroidism. In this report, we describe a case of fetal goiter identified in the 34th gestational week in a 41-year-old secundigravida with normal thyroid functions. A conservative approach was followed; the fetal goiter was monitored via ultrasound, which suggested this was a case of hyperthyroidism. After the birth, tests indicated that the newborn was euthyroidic. Consequently, a more detailed study using non-invasive procedures was deemed necessary to discover the precise cause of the fetal goiter during the gestational period.
Adult
;
Fetus
;
Goiter*
;
Humans
;
Hyperthyroidism
;
Hypothyroidism
;
Infant, Newborn
;
Magnetic Resonance Imaging
;
Parturition
;
Prenatal Diagnosis
;
Thyroid Gland
;
Ultrasonography
2.Association between decreased ovarian reserve and poor oocyte quality
Viviane Margareth SCANTAMBURLO ; Renate von LINSINGEN ; Lidio Jair Ribas CENTA ; Kahisa Fontana Dal TOSO ; Debora SCARABOTO ; Edward ARAUJO JÚNIOR ; Jaime KULAK JUNIOR
Obstetrics & Gynecology Science 2021;64(6):532-539
Objective:
To analyze the association between oocyte quality and decreased ovarian reserve (DOR) markers in young women undergoing controlled ovarian stimulation (COS).
Methods:
This retrospective study included 49 patients classified as having DOR based on anti-Müllerian hormone (AMH) levels, follicle-stimulating hormone (FSH) levels, or antral follicle counts (AFCs; <10). Images of all obtained oocytes were analyzed, and oocyte quality was classified according to maturity and morphology. The COS protocol utilized gonadotropin (FSH and/or human menopausal gonadotropin [hMG]) doses ranging from 150 to 300 IU/day. The Student’s t test or Mann-Whitney test was used to compare the groups. Spearman’s coefficients were estimated to verify the correlation between the administered dose of FSH/hMG and the number of mature oocytes. To evaluate the association between patient- and oocyte-related variables, logistic regression models were adjusted.
Results:
Women with DOR classified according to FSH level had more immature oocytes (P<0.001). Women with DOR according to AMH had fewer mature oocytes and increased basal FSH levels (P<0.001). Women with DOR according to AFC had an increased risk of abnormally shaped oocytes (P=0.035).
Conclusion
This study showed that DOR based on AMH levels, FSH levels, and AFC was associated with poorer quality oocytes in young women who underwent COS.